Browsing by Author "Gaule, Carlos"
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Vega, Patricio; Gaule, Carlos; Mancilla, Jerson; Del Villar, Eugenia (1993)1. Liver microsomes from alloxan or streptozotocin diabetic rats displayed differential drug metabolizing abilities in vitro. 2. Only streptozotocin liver microsomes exhibited changes in the cytochrome P-450 normal spectral ...
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Villar, Eugenia del; Vega, Patricio; Gaule, Carlos; Sanchez, Emilio (1990)Short or long term diabetes in female rats produced remarkable activation of aminopyrine N-demethylation, inhibition of oestrone and p-nitrophenol glucuronidation and no changes in morphine UDP-glucuronyltransferase activity ...
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Vega, Patricio; Gaule, Carlos; Sanchez, Emilio; Villar, Eugenia del (1986)Short or long term alloxan diabetes produced activation of oestrone and morphine glucuronidation and inhibition of p-nitrophenol glucuronidation in rat liver microsomes. Insulin treatment restored decreased glucuronyltransferase ...
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Del Villar, Eugenia; Gaule, Carlos; Vega, Patricio (1995)1. 1. Streptozotocin-induced diabetes produced significant changes on the drug metabolizing enzyme machinery of rat kidney microsomes. 2. 2. It reduced the cytochrome P-450 content by 30%, this effect being reversed by ...