Browsing by Author "Izquierdo Lazo, Pamela Alejandra"

Now showing items 1-1 of 1

    • Liver microsomal biotransformation of nitro-aryl drugs: Mechanism for potential oxidative stress induction 
      Letelier Muñoz, María Eugenia; Izquierdo Lazo, Pamela Alejandra; Godoy Oviedo, Luis; Lepe Agrodnik, Ana María; Faúndez Cáceres, Mario Antonio (JOHN WILEY & SONS LTD, 2004-11)
      Toxic effects of several nitro-aryl drugs are attributed to the nitro-reduction that may be suffered in vivo, a reaction that may be catalysed by different reductases. One of these enzymes is NADPH-cytochrome P450 reductase, ...