Browsing by Author "Recabarren Gajardo, Gonzalo Iván"
Now showing items 1-9 of 9
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Castañeda Magliona, Fernando; Recabarren Gajardo, Gonzalo Iván; Hu, J.; Gillitt, N. D.; Bunton, Clifford A. (TAYLOR & FRANCIS LTD, 2003-11)The diacyl ylide, 3-triphenylphosphoranylidene-2,4-pentanedione (2) can adopt conformations stabilized by ylidic resonance with both acyl oxygens syn- or with one oxygen syn- and the other anti- to cationoid phosphorus, ...
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Mella Raipán, Jaime A.; Lagos, Carlos F.; Recabarren Gajardo, Gonzalo Iván; Espinosa Bustos, Christian; Romero Parra, Javier; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Carlos David (2013)A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 ...
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Mella Raipán, Jaime A.; Lagos, Carlos F.; Recabarren Gajardo, Gonzalo Iván; Espinosa Bustos, Christian; Romero Parra, Javier; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Carlos David (2013)A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 ...
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Espinosa Bustos, Christian; Lagos, Carlos F.; Romero Parra, Javier; Zárate, Ana M.; Mella Raipán, Jaime A.; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Iturriaga-Vásquez, Patricio; Tapia, Ricardo A.; Pessoa Mahana, Carlos David (Wiley-VCH Verlag, 2015)© 2015 Wiley-VCH Verlag GmbH & Co. KGaA. A series of N-acyl-2,5-dimethoxyphenyl-1H-benzimidazoles were designed based on a CoMFA model for cannabinoid receptor type 1 (CB1) ligands. Compounds were synthesized and radioligand ...
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Olea Azar, Claudio; Terraza, C. A.; Guerrero, J.; Rigol Olsen, Carolina; Recabarren Gajardo, Gonzalo Iván (SOCIEDAD CHILENA DE QUIMICA, 2002-09)Acrylamide can be polymerized using new catalytic systems. These are based on rhenium complexes as photosensitizers with triethylamine (TEA). Electron Spin Resonance (ESR) was used for the detection of radicals species ...
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Recabarren Gajardo, Gonzalo Iván (Universidad de Chile, 2008)La depresión es una grave patología neuropsiquiátrica caracterizada por síntomas de orden afectivo, cognitivo, motor y somático, la cual es desencadenada por una compleja interconexión de factores genéticos, de desarrollo ...
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Synthesis and Biological Screening of Novel Indolalkyl Arenes Targeting the Serotonine Transporter Ojeda Gómez, Claudia; Pessoa Mahana, Hernán; Iturriaga-Vásquez, Patricio; Pessoa Mahana, Carlos David; Recabarren Gajardo, Gonzalo Iván; Méndez Rojas, Claudio (Wiley, 2014)A series of functionalized indolylalkylarenes 3–16(a and b) were synthesized and their affinities for the serotonin transporter were investigated in vitro. Compounds 3–12(a and b) were obtained by nucleophilic substitution ...
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Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Temer, Jenny Fiedler; Zapata Torres, Gerald; Pessoa Mahana, Carlos David; Barría, Claudio Saitz; Araya Maturana, Ramiro (2012)A series of novel benzo[b]thiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1- one derivatives 6a-f, 7a-f and their corresponding alcohols 8a-f were synthesized and evaluated for their affinity towards 5-HT 1A receptors. The ...
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Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Fiedler Temer, Jenny; Zapata Torres, Gerald Amilcar; Pessoa Mahana, Carlos David; Saitz Barría, Claudio; Araya Maturana, Ramiro (2012)A series of novel benzobthiophen-2-yl-3-(4-arylpiperazin-1-yl)-propan-1-one derivatives 6a–f, 7a–f and their corresponding alcohols 8a–f were synthesized and evaluated for their affinity towards 5-HT1A receptors. The ...