Browsing by Subject "Gold nanorods"

Now showing items 1-8 of 8

    • Gold Nanoparticles Mediate Improved Detection of beta-amyloid Aggregates by Fluorescence 
      Jara Guajardo, Pedro; Cabrera, Pablo; Celis, Freddy; Soler Jauma, Mónica; Berlanga Mora, Isadora; Parra Muñoz, Nicole; Acosta, Gerardo; Albericio, Fernando; Guzmán, Fanny; Campos, Marcelo; Álvarez, Alejandra; Morales Zavala, Francisco; Kogan, Marcelo J. (MDPI, 2020)
      The early detection of the amyloid beta peptide aggregates involved in Alzheimer's disease is crucial to test new potential treatments. In this research, we improved the detection of amyloid beta peptide aggregates in vitro ...
    • Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide 
      Riveros Salvatierra, Ana; Eggeling, Cynthia; Riquelme Barrios, Sebastián; Adura, Carolina; López Iglesias, Carmen; Guzmán, Fanny; Araya Fuentes, Eyleen; Almada, Mario; Juárez, Josue; Valdez, Miguel A.; Fuentevilla Morgado, Ignacio; López, Olga; Kogan Bocian, Marcelo (Dove Medical Press, 2020)
      Introduction: Gold nanorods are highly reactive, have a large surface-to-volume ratio, and can be functionalized with biomolecules. Gold nanorods can absorb infrared electromagnetic radiation, which is subsequently dispersed ...
    • Improving gold nanorod delivery to the central nervous system by conjugation to the shuttle Angiopep-2 
      Velasco Aguirre, Carolina; Morales Zavala, Francisco; Salas Huenuleo, Edison; Gallardo Toledo, Eduardo; Andonie, Oscar; Muñoz, Luis; Rojas, Ximena; Acosta, Gerardo; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Albericio, Fernando; Kogan Bocian, Marcelo (Future Medicine, 2017)
      Aim: To improve the in vivo delivery of gold nanorods (GNRs) to the central nervous system of rats, these gold nanoparticles were conjugated to Angiopep-2, a shuttle peptide that can cross the blood-brain barrier. Materials ...
    • Ion pair method to determine the CTAB content in gold nanorods samples 
      Adura, Carolina; Guzman, Fanny; Álvarez Lueje, Alejandro; Kogan Bocian, Marcelo (Sociedad Chilena de Quimica, 2015)
      In this work, we report a fast and accessible method for quantification of cetyltrimethylammonium bromide (CTAB) in solutions of gold nanorods (GNRs) by bromophenol blue (BPB) ion-paring formation and spectrophotometric ...
    • Oligoarginine peptide conjugated to BSA improves cell penetration of gold nanorods and nanoprisms for ... 
      Bolaños, Karen; Sánchez Navarro, Macarena; Tapia Arellano, Andreas; Giralt, Ernest; Kogan, Marcelo Javier; Araya, Eyleen (MDPI, 2021)
      Gold nanoparticles (AuNPs) have been shown to be outstanding tools for drug delivery and biomedical applications, mainly owing to their colloidal stability, surface chemistry, and photothermal properties. The biocompatibility ...
    • Photothermal conversion efficiency and cytotoxic effect of gold nanorods stabilized with chitosan, alginate ... 
      Almada, M.; Leal Martínez, B. H.; Hassan, N.; Kogan Bocian, Marcelo; Burboa, M. G.; Topete, A.; Valdez, M. A.; Juarez, J. (Elsevier, 2017)
      Gold nanorods (GNR) use has been proposed in medical applications because of their intrinsic photothermal properties. However, the presence of CTAB molecules adsorbed onto the surface of GNRs results in a highly cytotoxic ...
    • Selective nanodecoration of modified cyclodextrin crystals with gold nanorods 
      Herrera, Bárbara; Adura, Carolina; Yutronic Sáez, Nicolás; Kogan Bocian, Marcelo; Jara Vergara, Paul (Elsevier, 2013)
      Gold nanorods (AuNRs) stabilized by cetyltrimethylammonium bromide (CTAB) were deposited onto crystals of a-cyclodextrin (a-CD) inclusion compounds (ICs) that contained octanethiol (OT) as guest molecules. The nanodecoration ...
    • The effects of gold nanoparticles functionalized with beta-amyloid specific peptides on an in vitro model ... 
      Ruffa, J.; Hüwelb, S.; Kogan Bocian, Marcelo; Simon, Ulrich; Joachim Gallab, Hans (Elsevier, 2017)
      We studied the effect of gold nanoparticle (AuNP) size, surface charge, concentration and morphology on the integrity of the blood–brain barrier (BBB) in a well-established in vitro model set-up. We focused on the effect ...