Now showing items 1721-1740 of 5198

    • Palma, Manuel; García, Paula; Márquez-Ruiz, Gloria; Vergara, Cristina; Robert Canales, Paz (Elsevier Ltd, 2014)
      Quercetin (Q), naringenin (N) and epicatechin (E) were encapsulated with inulin (In) as encapsulating agent and Capsul (C) as channelizing agent by spray drying and applying a Box-Behnken design. Q-In, N-In, E-In, Q-In-C, ...
    • Cañas, Alejandro; Richter Duk, Pablo (2012)
      Solid-phase microextraction of hexachlorobenzene from water was implemented for the first time on a rotating disk coated with an octadecyl-bonded silica (C 18) sorptive phase. The results indicate that the sorption performance ...
    • Aguilera Venegas, Benjamín; Speisky Cosoy, Hernán (Elsevier Inc., 2014)
      Up to date, attempts to locate the transition state (TS) for the trapping reaction between ̇OH and ̇DMPO have been unsuccessful, and the lack of molecular mechanisms by which ̇OH binds to the spin-trap constitutes a question ...
    • Cancino, Patricio; Paredes García, Verónica; Aguirre, Pedro; Spodine Spiridonova, Evgenia (Royal Society of Chemistry, 2014)
      The metal-organic framework [Cu2(bipy)2(btec)] ∞ was used as a heterogeneous catalyst in the liquid phase oxidation of styrene and cyclohexene with tert-butylhydroperoxide (TBHP) as the oxidant either in water-dichloroethane ...
    • Zolezzi Carvallo, Santiago; Moya, Sergio A.; Valdebenito, Gonzalo; Abarca, Gabriel; Parada Aliste, José; Aguirre, Pedro (John Wiley and Sons Ltd, 2014)
      Palladium(II) complexes containing phosphine donor ligands derived from naphthyl(diphenyl)phosphine were synthesized and characterized by NMR and elemental analysis. The complexes were studied as catalyst precursors in the ...
    • Pando, María Elsa; Bravo, Beatriz; Berrios, Macarena; Galdames, Andrea; Rojas, Catalina; Romero, Nalda; Camilo, Conrado; Encina, Cristian; Rivera, Matías; Rodríguez, Alicia; Aubourg, Santiago (Institute of Agricultural and Food Information, 2014)
      The urea complexation was used to concentrate n-3 fatty acids (FA) from crude and refined commercial salmon oils. The experimental procedure included salmon oil saponification, free fatty acid (FFA) collection, formation ...
    • Medina, Fernando; Quintremil, Sebastian; Alberti, Carolina; Barriga, Andres; Cartier Rovirosa, Luis; Puente, Javier; Ramírez, Eugenio; Ferreira, Arturo; Tanaka, Yuetsu; Valenzuela, Maria Antonieta (Mary Ann Liebert Inc., 2014)
      The human retrovirus human T cell lymphotropic virus type-I (HTLV-1) is the etiologic agent of HTLV-1-Associated myelopathy/tropical spastic paraparesis (HAM/TSP). Axonal degeneration in HAM/TSP patients occurs without ...
    • Manzur Saffie, Jorge; Vega, Andrés; Escuer, Albert (Elsevier Ltd, 2014)
      The synthesis, magnetic and structural characterization of two tetrameric copper(II) complexes {N(C4H9)4}-[Cu 2(LH)2(μ4-Br)Cu2(LH) 2](PF6)4 (1) and [Cu2(LH) 2(μ4-Cl)Cu2(LH)2](Cl) 2(PF6) (2) is described. LH stands for the ...
    • Morales, Javier O.; Huang, Siyuan; Williams, Robert O.; McConville, Jason T. (Elsevier, 2014)
      The goal of this investigation was to develop films containing insulin-coated nanoparticles and evaluate their performance in vitro as potential peptide delivery systems. To incorporate insulin into the films, a new ...
    • Hassan, Natalia; Oyarzún Ampuero, Felipe; Muñoz Lara, Pablo; Guerrero, Simón; Cabuil, Valérie; Abou-Hassan, Ali; Kogan Bocian, Marcelo (Bentham Science Publishers B.V., 2014)
      In this article we review the flow chemistry methodologies for the controlled synthesis of different kind of nano and microparticles for biomedical applications. Injection mechanism has emerged as new alternative for the ...
    • Nassif, Melissa; Valenzuela, Vicente; Rojas Rivera, Diego; Vidal, René; Matus, Soledad; Castillo, Karen; Fuentealba, Yerko; Kroemer, Guido; Levine, Beth; Hetz Flores, Claudio (Taylor and Francis Inc., 2014)
      Pharmacological activation of autophagy is becoming an attractive strategy to induce the selective degradation of aggregate-prone proteins. Recent evidence also suggests that autophagy impairment may underlie the pathogenesis ...
    • Acuña Rougier, C.; Jullian,; Olea Azar, Claudio (2012)
      Complexes formed by (±)-4′-hydroxyflavanone (OHFL) and the cyclodextrins β-cyclodextrin and (2-hydroxypropyl)-β-CD were obtained using the racemic mixture of the OHFL. These complexes were able to be studied due to their ...
    • Jara, José A.; Castro Castillo, Vicente; Saavedra-Olavarría, Jorge; Peredo, Liliana; Pavanni, Mario; Jaña, Fabián; Letelier, María Eugenia; Parra, Eduardo; Becker, María Inés; Morello Casté, Antonio; Kemmerling Weis, Ulrike; Maya Arango, Juan; Ferreira, Jorge (American Chemical Society, 2014)
      Tumor cells principally exhibit increased mitochondrial transmembrane potential (Δψm) and altered metabolic pathways. The therapeutic targeting and delivery of anticancer drugs to the mitochondria might improve treatment ...
    • Morales, Pablo E.; Torres, Gloria; Sotomayor Flores, Cristian Alejandro; Peña Oyarzún, Daniel; Rivera Mejías, Pablo; Paredes, Felipe; Chiong Lay, Mario (Academic Press Inc., 2014)
      Incretin GLP-1 has important metabolic effects on several tissues, mainly through the regulation of glucose uptake and usage. One mechanism for increasing cell metabolism is modulating endoplasmic reticulum (ER)-mitochondria ...
    • Pardo Jiménez, Viviana Gladys; Barrientos, C.; Pérez Cruz, Karina Angélica; Navarrete Encina, Patricio; Olea Azar, Claudio; Núñez Vergara, Luis; Squella Serrano, Juan (2014)
      In this paper, a series of six dihydropyridine-fused coumarins were synthesized and electrochemically characterized in dimethylformamide (DMF). Dihydropyridine ring oxidation on glassy carbon electrode (GCE) for condensed ...
    • Parada, Mirtha; Valenzuela Barra, Gabriela; Delporte, Carla; Lara Peñaloza, Hernán (Universidad de Santiago de Chile, 2014)
      The estrous cycle disruptor effect of an ethanolic extract (EMATst) from Buddleja globosa leaves and standardized in its main component (verbascoside) was determined in rats after the subcutaneous administration of EMATst. ...
    • Ocaranza, Maria Paz; Moya, Jackeline; Barrientos, Victor; Alzamora, Rodrigo; Hevia, Daniel; Morales, Cristobal; Pinto, Melissa; Escudero, Nicolás; García Nannig, Lorena; Novoa, Ulises; Ayala, Pedro; Díaz Araya, Guillermo; Godoy, Ivan; Chiong Lay, Mario; Lavandero González, Sergio; Jalil Milad, Jorge (Lippincott Williams and Wilkins, 2014)
      BACKGROUND:: Little is known about the biological effects of angiotensin-(1-9), but available evidence shows that angiotensin-(1-9) has beneficial effects in preventing/ameliorating cardiovascular remodeling. OBJECTIVE:: ...
    • Mena, Juan F.; Neira Carrillo, Andrónico; Yazdani-Pedram Zobeiri, Mehrdad; Kogan Bocian, Marcelo (American Scientific Publishers, 2013)
      With the purpose of obtaining stable and non-toxic nanocomposites with potential biomedical applications we coated gold nanoparticles (AuNP) with chitosan (CHI) and CHI grafted with poly(Nisopropilacrylamide) (PNIPAAm) and ...
    • Riveros, Ana; Dadlani, Komal; Salas, Edison; Caballero, Leonardo; Melo, Francisco; Kogan Bocian, Marcelo (American Scientific Publishers, 2013)
      There has been an increase in the research towards the use of nanoparticles as a promising tool for nanomedicine, from imagenology, drug and gene delivery, to phototherapy. Little is known regarding the interaction between ...
    • Pérez, M. De Los A.Arada; Yazdani-Pedram Zobeiri, Mehrdad (2013)
      ABSTRACT Chloride selective polymeric liquid membrane electrode has been developed by using Bis-(2-ethylhexyl) Sebacate (DOS) as plasticizer and 2-[5-(4-nitrophenyl) furyl]-4,5-diphenyl imidazole (FFDFIN) as ionophore. ...