Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 1861-1880 of 5198

    • Development of an ingredient containing apple peel, as a source of polyphenols and dietary fiber 
      Henríquez, Carolina; Speisky Cosoy, Hernán; Chiffelle, Italo; Valenzuela, Tania; Araya, Manuel; Simpson, Ricardo; Almonacid, Sergio (2010)
      Apple peel is a waste product from dried apple manufacture. The content of phenolic compounds, dietary fiber, and mineral are higher in apple peel, compared to other edible parts of this fruits. The objective of this study ...
    • Electrochemical behavior of atomoxetine and its voltammetric determination in capsules 
      Pérez-Ortiz, M.; Muñoz, C.; Zapata Urzúa, Claudio; Álvarez Lueje, Alejandro (Elsevier B.V., 2010)
      In this work, the electrochemical behavior and the analytical application of atomoxetine, a selective noradrenaline reuptake inhibitor, are studied. Atomoxetine, studied by differential pulse voltammetry and cyclic voltammetry ...
    • Study of the variational patterns for corrosion kinetics of carbon steel as a function of dissolved oxygen ... 
      Cáceres, L.; Vargas Valero, Tomás; Parra, M. (Elsevier Ltd, 2009)
      The simultaneous occurrences of electrochemical reactions responsible for corrosion of carbon steel in NaCl solutions have been analyzed on the basis of the mixed potential theory in order to determine the combined effect ...
    • Proliferation of human mammary cancer cells exposed to 27-hydroxycholesterol 
      Cruz, Pamela; Torres, Cristian; Ramírez, María Eugenia; Epuñán, María José; Valladares Boasi, Luis; Sierralta, Walter Daniel (2010)
      The aim of the present study was to identify the possible mechanisms by which certain estradiol receptor (ER)-positive mammary tumor cells remain resistant to treatment with anti-estrogens or inhibitors of local estradiol ...
    • Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced ... 
      Chiong Lay, Mario; Parra, V.; Eisner, V.; Ibarra, C.; Maldonado, C.; Criollo Céspedes, Alfredo; Bravo, R.; Quiroga, C.; Contreras, A.; Vicencio Bustamante, José; Cea, P.; Bucarey, J.; Molgó, Jordi; Jaimovich Pérez, Enrique; Hidalgo Tapia, María Cecilia; Kroemer, G.; Lavandero González, Sergio (2010)
      Hyperosmotic stress promotes rapid and pronounced apoptosis in cultured cardiomyocytes. Here, we investigated if Ca2+ signals contribute to this response. Exposure of cardiomyocytes to sorbitol [600 mosmol (kg water)(-1)] ...
    • Electrochemistry of interaction of 2-(2-nitrophenyl)-benzimidazole derivatives with DNA 
      Catalán, Mabel; Álvarez Lueje, Alejandro; Bollo Dragnic, Soledad (2010)
      In this study the interaction between new benzimidazole molecules, 2-(2-nitrophenyl)-1H-benzimidazole (NB) and N-benzoyl-2-(2-nitrophenyl)-benzimidazole (BNB), with dsDNA and ssDNA was assessed at pH 7.4. Using differential ...
    • Multifunctionalized gold nanoparticles with peptides targeted to gastrin-releasing peptide receptor of a ... 
      Hosta-Rigau, Leticia; Olmedo, Ivonne; Arbiol, Jordi; Cruz, Luis J.; Kogan Bocian, Marcelo; Albericio, Fernando (2010)
      Functionalization of gold nanoparticles (AuNPs) with both a targeting peptide (an analogue of the peptide Bombesin) and a drug peptide ligand (an analogue of the RAF peptide) with the aim of improving selectivity in the ...
    • Voltammetric behavior of naratriptan and its determination in tablets 
      Velasco Aguirre, Carolina; Álvarez Lueje, Alejandro (Elsevier B.V., 2010)
      The electrochemical behavior and the analytical application of the selective serotonin agonist naratriptan (N-methyl-3-(1-methyl-4-piperidyl)indole-5-ethanesulfonamide) are presented herein. Naratriptan exhibits an anodic ...
    • Spectroscopic characterization of the inclusion complexes of luteolin with native and derivatized β-cyclodextrin 
      Jullian Matthaei, Carolina; Cifuentes, Constanza; Alfaro, Muriel; Miranda, Sebastián; Barriga, Germán; Olea Azar, Claudio (2010)
      The inclusion complexes of Luteolin (LU) with cyclodextrins (CDs) including β-cyclodextrin (βCD), hydroxypropyl-β-cyclodextrin (HPβCD) and dimethyl-β-cyclodextrin (DMβCD), Scheme 1, have been investigated using the method ...
    • Acute and subchronic toxicological study of senna in rodents Toxicología aguda y subcrónica de una pasta ... 
      Hancke, Juan; Cáceres, Dante; Burgos, Rafael A.; Hernández, Doris; Rojas, Armando; Morales, Miguel A. (2009)
      Senna crude herbal paste, CIRUELAX®, laxative used in America and Spain, was administered by oral gavage to mice and rats once daily in doses from 2 to 10 g/kg for 7 days. LD50 was rated as higher than 10 g/kg. To determine ...
    • Evaluation of the antioxidant properties and effects on the biotransformation of commercial herbal preparations ... 
      Letelier, María Eugenia; Cortes, Juan; Lepe, Ana; Jara, José; Molina Berríos, Alfredo; Rodriguez, Carmen; Iturra-Montecinos, Pablo; Faúndez, Mario (2009)
      The antioxidant herbal ingredients are xenobiotics for animals, many of them must be biotransformed to be eliminated, especially lipophilic compounds. Biotransformation of such xenobiotics- occurs mainly in the hepatic ...
    • Magnetic manganese dioxide as an amphoteric adsorbent for removal of harmful inorganic contaminants from water 
      Calderon Rosas, Carla; Franzreb, Matthias; Valenzuela, Fernando; Höll, Wolfgang (2010)
      Manganese dioxide (δ-MnO2) with magnetic properties has been synthesized by precipitation of MnO2 in the presence of magnetite. The resulting material has a particle size distribution between 0.5 and 5 μm. Magnetization ...
    • Improvement of galangin solubility using native and derivative cyclodextrins. An UV-Vis and NMR study 
      Jullian Matthaei, Carolina (2009)
      The slightly water-soluble flavonoid galangin (G) and its inclusion with either β-cyclodextrin (βCD), hydroxypropyl-β-cyclodextrin (HPβCD) or Heptakis-2,6-O-di methyl-β-cyclodextrin (DMβCD) were investigated. The stoichiometric ...
    • Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured ... 
      Marambio, Paola; Toro, Barbra; Sanhueza, Carlos; Troncoso, Rodrigo; Parra, Valentina; Verdejo, Hugo; García Nannig, Lorena; Quiroga, Clara; Munafo, Daniela; Díaz Elizondo, Jessica; Bravo Sagua, Roberto; González Burgos, María Julieta; Díaz Araya, Guillermo; Pedrozo Cibils, Zully; Chiong Lay, Mario; Co (2010)
      Aggresomes are dynamic structures formed when the ubiquitin-proteasome system is overwhelmed with aggregation-prone proteins. In this process, small protein aggregates are actively transported towards the microtubule-organizing ...
    • Assessment of extractability of Cu, Cr, Ni, Pb and Zn in some chilean biosolid-amended soils by using BCR ... 
      Ahumada, Inés; Maricán, Adolfo; Retamal, Mauricio; Pedraza, Cristina; Ascar, Loreto; Carrasco, Adriana; Richter Duk, Pablo (Sociedade Brasileira de Quimica, 2010)
      The effect of biosolid application on the distribution and extractability of Cr, Cu, Ni, Pb, and Zn was assessed in Mollisol soils from an important agricultural zone in central Chile. These were amended with biosolids at ...
    • Determination of low molecular weight carbohydrates in Cabernet sauvignon red wines 
      Matsuhiro, Betty; Torres, Rodrigo; Zúñiga, Elisa A.; Aguirre, Maria J.; Mendoza, Leonora; Isaacs, Mauricio (Sociedad Chilena de Quimica, 2009)
      Low molecular weight carbohydrates (LMW) were determined in a Chilean Cabernet Sauvignon red wine by the Dubois method, a specific method for the determination of carbohydrates. Dialysis treatment of red wine allowed the ...
    • Revision and phylogenetics of the genus Paraulax Kieffer (Hymenoptera, Cynipidae) with biological notes and ... 
      Nieves-Aldrey, José Luis; Liljeblad, Johan; Nieves, María Hernández; Grez Villarroel, Audrey; Nylander, Johan A.A. (2009)
      The gall wasp genus Paraulax (Hymenoptera, Cynipidae) associated with southern beeches (Nothofagus (Nothofagaceae)) from South America is revised. The genus Paraulax and its type species, P. perplexa, are redescribed and ...
    • Solvent-free microwave-promoted Michael addition of azanucleophiles to benzo[b]thiophen-2-yl-2-propenone 
      Pessoa Mahana, Hernán; González, Marcos; González, Marcelo; Pessoa Mahana, David; Araya Maturana, Ramiro; Ron, Nadia; Saitz Barría, Claudio (Arkat, 2009)
      A series of Michael adducts (5-11) have been synthesized with good yields under solvent-free microwave conditions. Aliphatic and aromatic amines utilized as Michael donors reacted with 1-(4,7-dimethoxybenzo[b]thiophen-2- ...
    • Contraction-related stimuli regulate GLUT4 traffic in C2C 12-GLUT4myc skeletal muscle cells 
      Niu, Wenyan; Bilan, Philip J.; Ishikura, Shuhei; Schertzer, Jonathan D.; Contreras Ferrat, Ariel Eduardo; Fu, Zhengxiang; Liu, Jie; Boguslavsky, Shlomit; Foley, Kevin P.; Liu, Zhi; Li, Jinru; Chu, Guilan; Panakkezhum, Thomas; Lopaschuk, Gary D.; Lavandero González, Sergio; Yao, Zhi; Klip (2010)
      Muscle contraction stimulates glucose uptake acutely to increase energy supply, but suitable cellular models that faithfully reproduce this complex phenomenon are lacking. To this end, we have developed a cellular model ...
    • Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro 
      Ocaranza, Maria Paz; Lavandero González, Sergio; Jalil Milad, Jorge; Moya, Jaqueline; Pinto, Melissa; Novoa, Ulises; Apablaza, Felipe; González, Leticia; Hernández, Carol; Varas, Manuel; López, René; Godoy, Iván; Verdejo, Hugo; Chiong Lay, Mario (Lippincott Williams and Wilkins, 2010)
      Background: Angiotensin-(1-9) is present in human and rat plasma and its circulating levels increased early after myocardial infarction or in animals treated with angiotensin-converting enzyme inhibitor. However, the ...