Facultad de Ciencias Químicas y Farmacéuticas: Recent submissions

Now showing items 981-1000 of 5196

    • Deltamethrin determination in natural water samples via photochemically-induced fluorescence coupled to ... 
      Veneciano, Rodrigo I.; Parra, V. Sonnia; Quiroz, Waldo; Fuentes Pérez, Edwar; Aguilar, Luis F.; Bravo, Manuel A. (Elsevier, 2020)
      In this work, an analytical method for deltamethrin determination in natural waters based on photochemicallyinduced fluorescence coupled to third-order/four-way calibration was evaluated and compared with secondorder/three-way ...
    • Drug-loaded lipid-core micelles in mucoadhesive films as a novel dosage form for buccal administration of ... 
      Chou, Wai-Houng; Galaz, Ariel; Jara, Miguel O.; Gamboa, Alexander; Morales Montecinos, Javier (MDPI, 2020)
      The aim of the study was to develop a novel buccal dosage form to transport rhodamine 123 and human insulin as models for poorly water-soluble and biological drugs, using lipid-core micelles (LCMs)-loaded mucoadhesive ...
    • Editorial: celebrating 40 years of the chilean society of pharmacology 
      Yévenes, Gonzalo E.; Bravo, Javier A.; Díaz Araya, Guillermo; Sotomayor Zárate, Ramón; Fiedler Temer, Jenny; Reyes Parada, Miguel; Fuentealba, Jorge (Frontiers Media, 2020)
    • Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human ... 
      DebRoy, Sruti; Aliaga Tobar, Víctor; Gálvez, Gabriel; Arora, Srishtee; Liang, Xiaowen; Horstmann, Nicola; Maracajá Coutinho, Vinicius; Latorre Mora, Mauricio; Hook, Magnus; Flores, Anthony; Shelburne, Samuel A. (Wiley, 2020)
      Catabolite control protein A (CcpA) is a master regulator of carbon source utilization and contributes to the virulence of numerous medically important Gram-positive bacteria. Most functional assessments of CcpA, including ...
    • Light-induced release of the cardioprotective peptide angiotensin-(1-9) from thermosensitive liposomes with ... 
      Bejarano, Julián; Rojas, Aldo; Ramírez Sagredo, Andrea; Riveros Salvatierra, Ana; Morales Zavala, Francisco; Flores, Yvo; Riquelme Meléndez, Jaime; Guzmán, Fanny; Araya, Eyleen; Chiong Lay, Mario; Ocaranza, María Paz; Morales Montecinos, Javier; Villamizar Sarmiento, María Gabriela; Sánchez Vergara, Gina; Lavandero González, Sergio; Kogan, Marcelo J. (Elsevier, 2020)
      Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half-life in blood. This peptide has shown to prevent and/or attenuate hypertension and cardiovascular remodeling. A controlled ...
    • Incorporation of NiO into SiO2, TiO2, Al2O3, and Na4.2Ca2.8(Si6O18) matrices: medium effect on the optical ... 
      Alvarado Díaz, Carlos; Valenzuela, María L.; Cifuentes Vaca, Olga; Segovia, Marjorie; Laguna Bercero, Miguel A. (MDPI, 2020)
      The medium effect of the optical and catalytic degradation of methylene blue was studied in the NiO/SiO2, NiO/TiO2, NiO/Al2O3, and NiO/Na4.2Ca2.8(Si6O18) composites, which were prepared by a solid-state method. The new ...
    • Influence of the Location of Ascorbic Acid in Walnut Oil Spray-Dried Microparticles with Outer Layer on the ... 
      Cáceres, Denisse; Giménez, Begoña; Marquez Ruiz, Gloria; Holgado, Francisca; Vergara, Cristina; Romero Hasler, Patricio; Soto Bustamante, Eduardo; Robert Canales, Paz (MDPI, 2020)
      Purified walnut oil (PWO) microparticles with Capsul(R) (C, encapsulating agent), sodium alginate (SA) as outer layer and ascorbic acid (AA) as oxygen scavenger were obtained by spray drying using a three-fluid nozzle. AA ...
    • Manipulation of ACE2 expression in COVID-19 
      Chaudhry, Farhan; Lavandero González, Sergio; Xie, Xiang; Sabharwal, Basera; Zheng, Ying-Ying; Correa, Ashish; Narula, Jagat; Levy, Phillip (BMJ, 2020)
      SARS-CoV-2 is the virus responsible for the ongoing COVID-19 outbreak. The virus uses ACE2 receptor for viral entry. ACE2 is part of the counter-regulatory renin-angiotensin-aldosterone system and is also expressed in the ...
    • Poly-epsilon-caprolactone Nanoparticles Loaded with 4-Nerolidylcatechol (4-NC) for Growth Inhibition of ... 
      Greatti, Vanessa Raquel; Oda, Fernando; Sorrechia, Rodrigo; Kapp, Bárbara Regina; Seraphim, Carolina Manzato; Villas Boas Weckwerth, Ana Carolina; Chorilli, Marlus; Da Silva, Patricia Bento; Eloy, Josimar O.; Kogan, Marcelo J.; Morales Montecinos, Javier; Linhari Rodrigues Pietro, Rosemeire Cristina (MDPI, 2020)
      Dermatophyte fungal infections are difficult to treat because they need long-term treatments. 4-Nerolidylcatechol (4-NC) is a compound found in Piper umbellatum that has been reported to demonstrate significant antifungal ...
    • DARK Classics in chemical neuroscience: Heroin and desomorphine 
      Mella Raipán, Jaime; Romero Parra, Javier; Recabarren Gajardo, Gonzalo (American Chemical Society, 2020)
      Opioids are arguably one of the most important pharmacologic classes, mainly due to their rich history, their useful and potent analgesic effects, and also, just as importantly, their “Dark Side”, constituted by their ...
    • Inhibition of soybean 15-lipoxygenase and human 5-lipoxygenase by extracts of leaves, stem bark, phenols ... 
      Muñoz Ramírez, Alejandra; Mascayano Collado, Carolina; Barriga, Andrés; Echeverría, Javier; Urzúa, Alejandro (Frontiers Media, 2020)
      Lithraea caustica (Molina) Hook. and Arn. (Anacardiaceae), common name Litre, is an evergreen endemic plant used in the Mapuche Chilean folk medicine. The stem juice of L. caustica mixed with Rubus ulmifolius (blackberry) ...
    • Electrochemistry and reactivity against superoxide anion radicals of hydroxycoumarins and its derivatives 
      Barrientos, C; Navarrete Encina, P.; Squella Serrano, Juan (Electrochemical Soc Inc, 2020)
      The present studies reveal superoxide radical anion reactivity against synthesized coumarins. Free radicals play an important role in many diseases and they have a protective function also. Therefore, we must keep a balance ...
    • Electrocatalytic determination of NADH by means of electrodes modified with MWCNTs and nitroaromatic compounds 
      Contreras, G.; Barrientos, C; Moscoso, R.; Álvarez Lueje, Alejandro; Squella Serrano, Juan (Elsevier, 2020)
      In this work, we have both synthesized and studied 4-phenylbutyl-3,5-dinitrobenzoate (3,5-DNBPh) as a potential precursor of an electrocatalytic mediator for the oxidation of NADH, with the di-nitro compound immobilized ...
    • Chemical profiling, antioxidant, anticholinesterase, and antiprotozoal potentials of artemisia copa phil. ... 
      Larrazábal Fuentes, María José; Fernández Galleguillos, Carlos; Palma Ramírez, Jenifer; Romero Parra, Javier Hernán; Sepúlveda, Kevin; Galetovic, Alexandra; González, Jorge; Paredes, Adrián; Bórquez, Jorge; Simirgiotis, Mario J.; Echeverría, Javier (Frontiers Media, 2020)
      Artemisia copa Phil. (Asteraceae) (known as copa-copa) is a native species of Chile used as an infusion in traditional medicine by Atacamenos people in the Altiplano, highlands of northern Chile. In this research, we have ...
    • Nanostructured interfaces containing MWCNT and nitro aromatics: a new tool to determine Nimesulide 
      Moscoso, R.; Álvarez Lueje, Alejandro; Squella Serrano, Juan (Elsevier, 2020)
      A novel type of multiwalled carbon nanotube-modified glassy carbon electrode with an entrapped nimesulide drug was constructed. The new electrode surface was characterized by scanning electrochemical microscopy and scanning ...
    • The chemical compositions of essential oils derived from cryptocarya alba and laurelia sempervirens possess ... 
      Touma, Jorge; Navarro, Myriam; Sepúlveda, Betsabet; Pavón, Alequis; Corsini, Gino; Fernández, Katia; Quezada, Claudia; Torres, Angelo; Larrazabal Fuentes, María José; Paredes, Adrián; Neira, Iván; Ferrando, Matías; Bruna, Flavia; Venegas, Alejandro; Bravo, Jessica (MDPI, 2020)
      Cryptocarya alba (Peumo; CA) and Laurelia sempervirens (Laurel; LS) are herbs native to the Chilean highlands and have historically been used for medicinal purposes by the Huilliches people. In this work, the essential ...
    • Intranasal administration of gold nanoparticles designed to target the central nervous system: Fabrication ... 
      Gallardo Toledo, Eduardo; Tapia Arellano, Andreas; Celis, Freddy; Sinai, Tomer; Campos, Marcelo; Kogan, Marcelo J.; Sintov, Amnon C. (Elsevier, 2020)
      The presence of the blood-brain barrier (BBB) limit gold nanoparticles (GNP) accumulation in central nervous system (CNS) after intravenous (IV) administration. The intranasal (IN) route has been suggested as a good strategy ...
    • Acylglycerol synthesis including EPA and DHA from rainbow trout (Oncorhynchus mykiss) belly flap oil and ... 
      Pando, M. Elsa; Rodríguez Melis, Alicia; Valenzuela Pedevila, María Antonieta; Berríos, Macarena; Rivera, Matías; Romero Palacios, Nalda; Barriga, Andrés; Aubourg, Santiago (Springer, 2021)
      Supercritical carbon dioxide (SCCO2) was studied as a medium for the esterification of eicosapentaenoic acid (n-3 C20:5, EPA) or docosahexaenoic acid (n-3 C22:6, DHA) and caprylic acid (C8:0, CA) in structured triacylglycerols ...
    • Huperzine-A administration recovers rat ovary function after sympathetic stress 
      Riquelme, Raúl; Ruz, Freddy; Mayerhofer, Artur; Lara Peñaloza, Hernán (Wiley, 2020)
      Chronic cold stress affects ovarian morphology and impairs fertility in rats. It causes an ovarian polycystic ovary (PCOS)-like phenotype, which resembles PCOS in women. The mechanism of cold stress action involves increased ...
    • Exploiting the natural properties of extracellular vesicles in targeted delivery towards specific cells and tissues 
      Lara, Pablo; Chan, Alan B.; Cruz, Luis J.; Quest, Andrew F. G.; Kogan, Marcelo J. (MDPI, 2020)
      Extracellular vesicles (EVs) are important mediators of intercellular communication that participate in many physiological/pathological processes. As such, EVs have unique properties related to their origin, which can be ...