Facultad de Medicina: Recent submissions

Now showing items 1181-1200 of 13281

    • Mapping the human genetic architecture of COVID-19 
      COVID-19 Host Genetics Initiative (Nature, 2021)
      The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ...
    • Scaling of mortality in 742 metropolitan areas of the Americas 
      Bilal, Usama; Castro, Caio P. de; Alfaro Morgado, Tania; Barrientos Gutiérrez, Tonatiuh; Barreto, Mauricio L.; Leveau, Carlos M.; Martínez Folgar, Kevin; Miranda, J. Jaime; Montes, Felipe; Mullachery, Pricila; Pina, María Fátima; Rodríguez, Daniel A.; Dos Santos, Gervasio F.; Andrade, Roberto F. S.; Diez-Roux, Ana V. (Amer Assoc Advancement Science, 2021)
      We explored how mortality scales with city population size using vital registration and population data from 742 cities in 10 Latin American countries and the United States. We found that more populated cities had lower ...
    • Caracterización del inflamasoma nlrp3 en el músculo esquelético de ratones obesos insulino resistentes 
      Aguilera Miranda, Javiera Andrea (Universidad de Chile, 2020)
      El aumento global en la prevalencia de obesidad, insulino-resistencia (IR) y diabetes mellitus tipo 2 (DM2) se ha relacionado con cambios en patrones de estilo de vida y alimentación. Los mecanismos que median estas ...
    • A first in human trial implanting microalgae shows safety of photosynthetic therapy for the effective ... 
      Obaid Bobadilla, Miguel Luis; Camacho, Juan Pablo; Brenet, Marianne; Corrales Orovio, Rocío; Carvajal, Felipe; Martorell, Ximena; Werner, Consuelo; Simón, Valeska; Varas, Juan; Calderón Ortega, Wilfredo Luis; Guzmán, Christian Dani; Bono Merino, María Rosa; San Martín, Sebastián; Eblen Zajjur, Antonio; Egana, José Tomas (Frontiers Media, 2021)
      Insufficient oxygen supply represents a relevant issue in several fields of human physiology and medicine. It has been suggested that the implantation of photosynthetic cells can provide oxygen to tissues in the absence ...
    • Effect of CYP3A4, CYP3A5, MDR1 and POR genetic polymorphisms in immunosuppressive treatment in chilean ... 
      Contreras Castillo, Stephania Nichols; Plaza, Anita; Stojanova, Jana; Navarro, Gustavo; Carmona, Rodolfo; Corvalán, Fernando; Cerpa, Leslie; Sandoval, Christopher; Muñoz, Daniel; Leiva, Marina; Castañeda Sepúlveda, Luis Eduardo; Farías, Nayaret; Álvarez, Carolina; Llull Morchio, Gabriel Eduardo; Mezzano, Sergio; Ardiles, Leopoldo; Varela Figueroa, Nelson Miguel; Rodríguez, María S.; Flores, Claudio; Cayún, Juan Pablo; Krall Opazo, Paola Margarita; Quiñones Sepúlveda, Luis Abel (Frontiers Media, 2021)
      Cyclosporine (CsA) and tacrolimus (TAC) are immunosuppressant drugs characterized by a narrow therapeutic range and high pharmacokinetic variability. The effect of polymorphisms in genes related to the metabolism and ...
    • Interventions to reduce stigma towards mental disorders in young people: protocol for a systematic review ... 
      Núñez, Daniel; Martínez, Pablo; Borghero, Francesca; Campos, Susana; Martínez Nahuel, Vania Angélica (BMJ, 2021)
      Introduction The stigma towards mental disorders can limit the use and effectiveness of available mental health interventions for young people. We aim to systematically review effectiveness of interventions to reduce stigma ...
    • Efecto de la obesidad producida por una dieta alta en grasa sobre el balance óxido reducción celular en el corazón 
      Mujica Valenzuela, Isidora Andrea (Universidad de Chile, 2020)
      Introducción: ratones macho C57BL/6 alimentados con dieta alta en grasa por 12 semanas no presentan signos de estrés oxidativo en el corazón, a pesar de que desarrollan cambios metabólicos, como aumento de peso, resistencia ...
    • Increasing incidence of rotator cuff surgery: a nationwide registry study in Chile 
      Vidal, Catalina; Lira, María Jesús; Marinis, Rodrigo de; Liendo, Rodrigo; Contreras Fernández, Julio José (BMC, 2021)
      Background The rotator cuff surgery (RCS) incidence is rising rapidly in North America, Europe, Asia, and Australia. Despite this, multiple factors limit patients' access to surgery. In Latin America, barriers to orthopedic ...
    • Interprofessional health education teacher training at the University of Chile 
      Espinoza Barrios, Mónica Cecilia; Oyarzo Torres, Sandra Georgina (Korea Health Personnel Licensing Examination, 2021)
      The first interprofessional course that included students in the 8 undergraduate health programs at the Faculty of Medicine of the University of Chile was implemented in 2015. For the 700 students, 35 teachers were trained ...
    • An extensive Quality Control and Quality Assurance (QC/QA) Program significantly improves inter-laboratory ... 
      Maurer Granofszky, Margarita; Schumich, Angela; Buldini, Barbara; Gaipa, Giuseppe; Kappelmayer, Janos; Mejstrikova, Ester; Karawajew, Leonid; Rossi, Jorge; Suzan, Adin cinar; Agriello, Evangelina; Anastasiou Grenzelia, Theodora; Barcala, Virna; Barna, Gabor; Batinic, Drago; Bourquin, Jean-Pierre; Brueggemann, Monika; Bukowska Strakova, Karolina; Burnusuzov, Hasan; Carelli, Daniela; Deniz, Guennur; Dubravcic, Klara; Feuerstein, Tamar; Gaillard, Marie Isabel; Galeano, Adriana; Giordano, Hugo; González, Alejandro; Groeneveld Krentz, Stefanie; Hevessy, Zsuzsanna; Hrusak, Ondrej; Iarossi, María Belén; Jakso, Pal; Kloboves Prevodnik, Veronika; Kohlscheen, Saskia; Kreminska, Elena; Maglia, Óscar; Malusardi, Cecilia; Marinov, Neda; Martin, Bibiana María; Moeller, Claudia; Nikulshin, Sergey; Palazzi, Jorge; Paterakis, Georgios; Popov, Alexander; Ratei, Richard; Rodríguez, Cecilia; Sajaroff, Elisa Olga; Sala, Simona; Samardzija, Gordana; Sartor, Mary; Scarparo, Pamela; Sedek, Lukasz; Sedek, Lukasz; Solari, Liliana; Svec, Peter; Szczepanski, Tomasz; Taparkou, Anna; Torrebadell, Montserrat; Tzanoudaki, Marianna; Varotto, Elena; Vernitsky, Helly; Attarbaschi, Andishe; Schrappe, Martin; Conter, Valentino; Biondi, Andrea; Felice, Marisa; Campbell Bull, Myriam Florencia; Kiss, Csongor; Basso, Giuseppe; Dworzak, Michael N. (MDPI, 2021)
      Simple Summary Standardization of flow-cytometric assessment of minimal residual disease in acute lymphoid leukemia (ALL) is necessary to allow concordant multicentric application of the methodology. This is a prerequisite ...
    • Screening of COVID-19 cases through a Bayesian network symptoms model and psychophysical olfactory test 
      Eyheramendy, Susana; Saa, Pedro A.; Undurraga, Eduardo A.; Valencia, Carlos; López, Carolina; Méndez, Luis; Pizarro Berdichevsky, Javier Alejandro; Finkelstein Kulka, Andrés; Solari, Sandra; Salas, Nicolás; Bahamondes, Pedro; Ugarte, Martín; Barceló, Pablo; Arenas, Marcelo; Agosín, Eduardo (Cell, 2021)
      The sudden loss of smell is among the earliest and most prevalent symptoms of COVID-19 when measured with a clinical psychophysical test. Research has shown the potential impact of frequent screening for olfactory ...
    • Life expectancy and mortality in 363 cities of Latin America 
      Bilal, Usama; Hessel, Philipp; Pérez Ferrer, Carolina; Michael, Yvonne L.; Alfaro Morgado, Tania; Tenorio Mucha, Janeth; Friche, Amelia A. L.; Piña, María Fátima; Vives, Alejandra; Quick, Harrison; Alazraqui, Marcio; Rodríguez, Daniel A.; Miranda, J. Jaime; Diez Roux, Ana V. (Nature Research, 2021)
      The concept of a so-called urban advantage in health ignores the possibility of heterogeneity in health outcomes across cities. Using a harmonized dataset from the SALURBAL project, we describe variability and predictors ...
    • Treatment and outcome analysis of 639 relapsed non-hodgkin lymphomas in children and adolescents and resulting ... 
      Burkhardt, Birgit; Taj, Mary; Garnier, Nathalie; Minard Colin, Veronique; Hazar, Volkan; Mellgren, Karin; Osumi, Tomoo; Fedorova, Alina; Myakova, Natalia; Verdu Amoros, Jaime; Andres, Mara; Kabickova, Edita; Attarbaschi, Andishe; Chiang, Alan Kwok Shing; Bubanska, Eva; Donska, Svetlana; Hjalgrim, Lisa Lyngsie; Wachowiak, Jacek; Pieczonka, Anna; Uyttebroeck, Anne; Lazic, Jelena; Loeffen, Jan; Buechner, Jochen; Niggli, Félix; Csoka, Monika; Krivan, Gergely; Palma Behnke, Julia Irene; Burke, G. A. Amos; Beishuizen, Auke; Koeppen, Kristin; Mueller, Stephanie; Herbrueggen, Heidi; Woessmann, Wilhelm; Zimmermann, Martin; Balduzzi, Adriana; Pillon, Marta (MDPI, 2021)
      Simple Summary: Despite very poor survival, controversies remain in the treatment for refractory or relapsed non-Hodgkin lymphoma (r/r NHL) in children and adolescents. The current project identifies and reports international ...
    • The meaning of postpartum sexual health for women living in Spain: a phenomenological inquiry 
      Pardell Domínguez, Lidia; Palmieri, Patrick A.; Domínguez Cancino, Karen Aileen; Camacho Rodríguez, Doriam E.; Edwards, Joan E.; Watson, Jean; Leyva Moral, Juan M. (BMC, 2021)
      Background: Sexual health is a multidimensional phenomenon constructed by personal, social, and cultural factors but continues to be studied with a biomedical approach. During the postpartum period, a woman transitions ...
    • Identification of Recent Tuberculosis Exposure Using QuantiFERON-TB Gold Plus, a Multicenter Study 
      Pérez Recio, Sandra; Pallares, Natalia; Grijota Camino, María D.; Sánchez Montalva, Adrián; Barcia, Laura; Campos Gutiérrez, Silvia; Pomar, Virginia; Rabunal Rey, Ramón; Balcells, María Elvira; Gazel, Déniz; Montiel, Natalia; Vicente, Diego; Goic Barisic, Ivana; Schon, Thomas; Paues, Jakob; Marekovic, Ivana; Cacho Calvo, Juana; Barac, Aleksandra; Goletti, Delia; Garcia Gasalla, Mercedes; Barcala, José María; Tórtola, María Teresa; Anibarro, Luis; Suárez Toste, Isabel; Moga, Esther; Gude González, María J.; Naves Pichuante, Rodrigo Antonio; Karsligil, Tekin; Martin Penaranda, Tania; Stevanovic, Goran; Trigo, Matilde; Rubio, Verónica; Karaoglan, Ilkay; Bayram, Nazan; Alcaide, Fernando; Tebe, Cristian; Santin, Miguel (Amer Soc Microbiology, 2021)
      We investigated whether the difference of antigen tube 2 (TB2) minus antigen tube 1 (TB1) (TB22TB1) of the QuantiFERON-TB gold plus test, which has been postulated as a surrogate for the CD81 T-cell response, could be ...
    • Encuentro de rehabilitación comunitaria en Latinoamérica: experiencias en pandemia: registro de presentaciones 
      Bustos García, Brenda; Rodríguez García, Rosa; Droguett Cervela, Ramón; Mora Rodríguez, Cristal; Maldonado Goyzueta, Paola; Manríquez Hizaut, Mónica; Rodrigues Arce, Vladimir Andrei; Pérez Ramírez, Berenice; Anau, Flavia; Henríquez, Raquel; Balboa Oyarce, Olga; Sánchez Hernández, Óscar (Universidad de Chile. Facultad de Medicina. Departamento de Kinesiología. Núcleo Desarrollo Inclusivo, 2020)
      Versión escrita del "Encuentro Latinoamericano sobre Rehabilitación Comunitaria", realizado en mayo 2021, por el Núcleo Desarrollo Inclusivo con apoyo del proyecto Internacionalización de la Vicerrectoría de Investigación ...
    • Smartphone screen testing, a novel pre-diagnostic method to identify SARS-CoV- 2 infectious individuals 
      Young, Rodrigo M.; Solis, Camila J.; Barriga Fehrman, Andrés; Abogabir, Carlos; Thadani, Álvaro R.; Labarca, Mariana; Bustamante, Eva; Tapia, Cecilia V.; Sarda, Antonia G.; Sepúlveda, Francisca; Pozas, Nadia; Cerpa, Leslie C; Lavanderos, María A.; Varela Figueroa, Nelson Miguel Edgardo; Santibáñez, Álvaro; Sandino, Ana M.; Reyes López, Felipe; Dixon, Garth; Quiñones Sepúlveda, Luis Abel (Elife Sciences Publications, 2021)
      The COVID-19 pandemic will likely take years to control globally, and constant epidemic surveillance will be required to limit the spread of SARS-CoV-2, especially considering the emergence of new variants that could ...
    • Rol de los laboratorios públicos en el diagnóstico SARS-CoV-2 en la pandemia de COVID-19: Experiencia, ... 
      Acevedo Muñoz, William; Benadof Fuentes, Dona Nurith; Farfán Urzúa, Mauricio Javier (Soc chilena Infectología, 2021)
    • Evaluation of changes produced by cadmium on the expression of genes regulated by NF-Kb in macrophages and ... 
      López Contreras, Pamela Andrea (Universidad de Chile, 2018)
      Atherosclerosis is the main risk factor for cardiovascular diseases and cigarette smoking is a major risk factor to develop cardiovascular diseases and atherosclerosis. A transcriptome study of circulating monocytes from ...
    • Fisuras orofaciales en Chile : asociación entre niveles de metilación global del ADN y variantes genéticas ... 
      Cáceres Rojas, Gabriela Andrea (Universidad de Chile, 2020)
      En la etiología de las fisuras orofaciales no sindrómicas (FOFNS) el metabolismo de los folatos jugaría un importante rol, en donde se han reportado asociaciones con variantes hipofuncionales de genes de este metabolismo ...