Browsing by Author "Quintanilla, Miguel"
Now showing items 1-4 of 4
-
Santibáñez, Juan Francisco; Kocic, Jelena; Fabra, Angels; Cano, Amparo; Quintanilla, Miguel (ELSEVIER, 2010)Transforming growth factor-b1 (TGF-b1) activates Rac1 GTPase in mouse transformed keratinocytes. Expression of a constitutively active Q61LRac1 mutant induced an epithelial to mesenchymal transition (EMT) linked to ...
-
Santibáñez, Juan Francisco; Quintanilla, Miguel; Martínez, Jorge (Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies., 2002-04-18)We have examined the effect of transforming growth factor L1 (TGF-L1) and overexpression of the Smad4 gene on the phenotype of Car C, a ras mutated highly malignant spindle carcinoma cell line. TGF-L1-treated Car C cells ...
-
Santibañez, Juan Francisco; Guerrero, Javier; Quintanilla, Miguel; Fabra, Angels; Martínez, Jorge (Elsevier Science (USA), 2002-07-15)Mouse transformed keratinocytes cultured in the presence of transforming growth factor-b1 (TGF-b1) acquire a set ofmorphological and functional properties giving rise to a more motile phenotype that expresses mesenchymal ...
-
Santibañez, Juan Francisco; Frontelo, Pilar; Iglesias, Maite; Martínez, Jorge; Quintanilla, Miguel (Wiley-Liss, Inc., 1999)Transforming growth factor b1(TGF-b1) is a stimulator of malignant progression in mouse skin carcinogenesis. TGF-b1 exerts a differential effect on cultured nontumorigenic (MCA3D cell line) and transformed (PDV cell line) ...