Now showing items 261-280 of 925

    • Ramírez Saavedra, Carolina; Coronado, Jaime; Silva, Arturo; Romero Ormazábal, Jaime (MDPI, 2018)
      Arapaima gigas is a large air-breathing fish found in Amazonian rivers, a characteristic that gives this species an advantage in oxygen-deprived waters. It shows high potential for aquaculture in the Amazon region due ...
    • Pérez Bazán, Álvaro; Arenas Rojas, Pamela; Carrasco Naranjo, Fernando; Basfi-fer Obregón, Karen; Pérez Bravo, Francisco; Codoceo, Juana; Inostroza Escobar, Jorge; Galgani, José E.; Gilmore, L. Anne; Ruz Ortiz, Manuel (Elsevier, 2018)
      Background/objective: Interest in healthy properties of food and nutrients as co-adjuvant in type-2 diabetes therapy has increased in recent years. Zinc supplementation trials have shown improvements in glycemic control in ...
    • Latorre Mora, Mauricio; Quenti, Daniela; Travisany, Dante; Singh, Kavindra V.; Murray, Barbara E.; Maass Sepúlveda, Alejandro; Cambiazo Ayala, Verónica (Frontiers Media, 2018)
      The ferric uptake regulator (Fur) plays a major role in controlling the expression of iron homeostasis genes in bacterial organisms. In this work, we fully characterized the capacity of Fur to reconfigure the global ...
    • Salvatore, Silvia; Abkari, Abdelhak; Cai, Wei; Catto-Smith, Anthony; Cruchet Muñoz, Sylvia; Gottrand, Frederic; Hegar, Badriul; Lifschitz, Carlos; Ludwig, Thomas; Shah, Neil; Staiano, Annamaria; Szajewska, Hania; Treepongkaruna, Suporn; Vandenplas, Yvan (Blackwell, 2018)
      Aim: Regurgitation, infantile colic and functional constipation are common functional gastrointestinal disorders (FGIDs) during infancy. Our aim was to carry out a concise review of the literature, evaluate the impact of ...
    • Guarino, Alfredo; Lo Vecchio, Andrea; Amil Dias, Jorge; Berkley, James A.; Boey, Chris; Bruzzese, Dario; Cohen, Mitchell B.; Cruchet Muñoz, Sylvia; Liguoro, Ilaria; Salazar Lindo, Eduardo; Sandhu, Bhupinder; Sherman, Philip M.; Shimizu, Toshiaki (Lippincott Williams, 2018)
      Objective: Despite a substantial consistency in recommendations for the management of children with acute gastroenteritis (AGE), a high variability in clinical practice and a high rate of inappropriate medical interventions ...
    • Garmendia Miguel, María Luisa; Matus, O.; Mondschein, S.; Kusanovic, J. P. (Elsevier, 2018)
      Objectives: We examined if the guidelines for gestational weight gain (GWG) proposed by the Institute of Medicine (IOM) are the most suitable for Chilean women. Study design: Secondary analysis of records of single ...
    • Tobar Bachler, Nicolás; Porras Espinoza, Omar; Smith, Patricio C.; Barros, L. Felipe; Martínez, Jorge (Wiley, 2017)
      Hyperglycemia is a risk factor for a variety of human cancers. Increased access to glucose and that tumor metabolize glucose by a glycolyticprocess even in the presence of oxygen (Warburg effect), provide a framework to ...
    • Martínez Arroyo, Ángela; Moreno Macías, Hortensia; Pereira Scalabrino, Ana; Garmendia Miguel, María Luisa (Routledge, 2017)
      Background: Metabolic syndrome (MetS) has been previously associated with an increased risk of breast cancer in postmenopausal women. Mammographic density (MD) is a marker of breast cancer risk. There is little evidence ...
    • Pérez Reytor, Diliana; Plaza, Nicolás; Espejo, Romilio T.; Navarrete, Paola; Bastías, Roberto; García, Katherine (Frontiers Media, 2017)
      In recent decades, the identification of small non-coding RNAs in bacteria has revealed an important regulatory mechanism of gene expression involved in the response to environmental signals and to the control of virulence. ...
    • Brito, Álex; Grapov, Dmitry; Fahrmann, Johannes; Harvey, Danielle; Green, Ralph; Miller, Joshua W.; Fedosov, Sergey N.; Shahab-Ferdows, Setareh; Hampel, Daniela; Pedersen, Theresa L.; Fiehn, Oliver; Newman, John W.; Uauy Dagach-Imbarack, Ricardo; Allen, Lindsay H. (American Society for Nutrition, 2017)
      Background:The specific metabolomic perturbations that occur in vitamin B-12 deficiency, and their associations withneurological function, are not well characterized.Objective:We sought to characterize the human serum ...
    • Parra, Alicia de la; García, María Ignacia; Hamilton, Valerie; Arias Pefaur, Carolina; Cabello Andrade, Juan Francisco; Cornejo Espinoza, Verónica (Elsevier, 2017)
      There is a consensus on the importance of early and life-long treatment for PKU patients. Still, differences existon target blood phenylalanine (Phe) concentrations for children with PKU in different countries and ...
    • Vásquez, F. D.; Corvalán Aguilar, Camila; Uauy Dagach-Imbarack, Ricardo; Kain Berkovic, Juliana (Nature, 2017)
      BACKGROUND/OBJECTIVE:To compare the association between anthropometric indicators of global and central obesity aspredictors of total body fat (TBF) and cardiometabolic risk factors in children.SUBJECTS/METHODS:A total of ...
    • Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)
      Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
    • Cabello Andrade, Juan Francisco; Marsden, Deborah (Dove Medical, 2017)
      Pompe disease (acid alpha-glucosidase deficiency, OMIM 232300) is a rare lysosomal storage disorder due to autosomal recessive mutations in the GAA gene. It has also been called acid maltase deficiency and glycogen storage ...
    • Garmendia Miguel, María Luisa; Mondschein, Susana; Matus, Omar; Murrugarra, Ruth; Uauy Dagach-Imbarack, Ricardo (Taylor and Francis, 2017)
      We identified factors associated with gestational weight gain (GWG) in 1,654 Chilean pregnant women with full-term pregnancies. At baseline, we collected information about sociodemographic, gyneco-obstetric, anthropometric, ...
    • Andrews, Mónica; Soto, Néstor; Arredondo Olguín, Miguel (2012)
      Background: The pharmacological action of metformin goes beyond mere glycemic control, decreasing markers of inflammation and contributing to the reduction of oxidative stress. Aim: To evaluate biochemical, anthropometric ...
    • Vizoso, Paula; Meisel, Lee A.; Tittarelli, Andrés; Latorre, Mariano; Saba, Juan; Caroca, Rodrigo; Maldonado, Jonathan; Cambiazo Ayala, Verónica; Campos Vargas, Reinaldo; González, Mauricio; Orellana, Ariel; Silva Ascencio, Herman (2009)
      Background: Cold storage is used to inhibit peach fruit ripening during shipment to distant markets. However, this cold storage can negatively affect the quality of the fruit when it is ripened, resulting in disorders ...
    • Echeverría, César; Santibáñez, Juan Francisco; Donoso Tauda, Óscar; Escobar, Carlos A.; Ramírez Tagle, Rodrigo (2009)
      Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2'-hydroxychalcones resulted in apoptosis induction ...
    • Rojas, Cecilia V.; Santa María, Lorena; Santos, José Luis; Cortés, Fanny; Alliende, María Angélica (2002)
      Complete achromatopsia is genetically heterogeneous and segregates with mutations in CNGA3 or CNGB3 genes, which respectively encode for α- and β-subunits of the cyclic-nucleotide-gated (CNG) cation channel expressed in ...
    • Ronco Macchiavello, Ana María; Llanos Silva, Miguel; Valladares Boasi, Luis (1993)
      The effect of human chorionic gonadotropin (hCG) on intact Leydig cell phospholipid methylation was studied. Hormonal stimulation of rat Leydig cells increased the incorporation of[methyl-3H]methionine into phospholipids ...