Browsing by Author "Arredondo, Miguel"
Now showing items 1-3 of 3
-
Arredondo, Miguel; Tapia, Victoria; Rojas, Alejandro; Aguirre, Pabla; Reyes, Francisca; Marzolo, Maria Paz; Núñez González, Marco (2006)Mutations in the HFE gene result in hereditary hemochromatosis, a disorder of iron metabolism characterized by increased intestinal iron absorption. Based on the observation that ectopic expression of HFE strongly inhibits ...
-
Intestinal epithelia (Caco-2) cells acquire iron through the basolateral endocytosis of transferrin Núñez González, Marco; Tapia, Victoria; Arredondo, Miguel (1996)Although the absorption of iron through the intestinal epithelia is inversely related to body iron stores, the mechanisms by which the enterocytes sense body iron stores are unknown. Polarized enterocytes have transferrin ...
-
Aguirre, Pabla; Mena, Natalia; Tapia, Victoria; Arredondo, Miguel; Núñez González, Marco (2005)Background: Iron is necessary for neuronal function but in excess generates neurodegeneration. Although most of the components of the iron homeostasis machinery have been described in neurons, little is known about the ...