Browsing by Author "Hetz Flores, Claudio"

Now showing items 1-3 of 3

    • Autophagy impairment: A crossroad between neurodegeneration and tauopathies 
      Nassif, Melissa; Hetz Flores, Claudio (2012)
      Most neurodegenerative diseases involve the accumulation of misfolded proteins in the nervous system. Impairment of protein degradation pathways such as autophagy is emerging as a consistent and transversal pathological ...
    • Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic ... 
      Medinas Bilches, Danilo; Rozas, Pablo; Martínez Traub, Francisca; Woehlbier, Ute; Brown, Robert H.; Bosco, Daryl A.; Hetz Flores, Claudio (National Academy of Sciences, 2018)
      Abnormal modifications to mutant superoxide dismutase 1 (SOD1) are linked to familial amyotrophic lateral sclerosis (fALS). Misfolding of wild-type SOD1 (SOD1(WT)) is also observed in postmortem tissue of a subset of ...
    • Prion function and pathophysiology in non-mammalian models 
      Guerrero, N.; Meynard, M. M.; Borgonovo, J.; Palma, K.; Concha Nordemann, Miguel; Hetz Flores, Claudio (Bentham Science Publishers B.V., 2017)
      © 2017 Bentham Science Publishers. More than thirty years have passed since the discovery of the prion protein (PrP) and its causative role in transmissible spongiform encephalopathy. Since a combination of both gain- and ...