Browsing by Author "Hurtado Guzmán, Claudio"

Now showing items 1-5 of 5

    • Geometrical isomerism in beta-nitrostyrenes: Preferred conformations of (E)- and (Z)-1-(4-methylthiopheny ... 
      Hurtado Guzmán, Claudio; Iturriaga-Vásquez, Patricio; Cassels Niven, Bruce; Zapata Torres, Gerald Amilcar (SOCIEDAD CHILENA DE QUIMICA, 2004-09)
      Condensation of 4-methylthiobenzaldehyde with 1-nitropropane unexpectedly afforded separable amounts of both (E)- and (Z)-1-(4-methylthiophenyl)-2-nitrobutene. The H-1 and C-13 NMR spectra allowed the unequivocal assignment ...
    • Geometrical isomerism in β-nitrostyrenes: Preferred conformations of (E)- and (E)-1-(4-methylthiophenyl)- ... 
      Hurtado Guzmán, Claudio; Iturriaga-Vásquez, Patricio; Zapata Torres, Gerald; Cassels Niven, Bruce (Sociedad Chilena de Quimica, 2004)
      Condensation of 4-methylthiobenzaldehyde with 1-nitropropane unexpectedly afforded separable amounts of both (E)- and (Z)-1-(4-methylthiophenyl)-2- nitrobutene. The 1H and 13C NMR spectra allowed the unequivocal assignment ...
    • Improving Amphetamine Therapeutic Selectivity: N,N-dimethyl-MTA has Dopaminergic Effects and does not Produce ... 
      Sotomayor Zárate, Ramón; Jara, Pablo; Araos, Patricio; Vinet, Raúl; Quiróz, Gabriel; Renard, Georgina M.; Espinosa, Pedro; Hurtado Guzmán, Claudio; Moya, Pablo R.; Iturriaga-Vásquez, Patricio; Gysling, Katia; Reyes Parada, Miguel (Nordic Pharmacological Society), 2014)
      Abstract: Amphetamine derivatives have therapeutic potential in diseases such as attention deficit hyperactivity disorder, narcolepsy and obesity. However, their prolonged use has been associated with cardiovascular ...
    • Monoamine Oxidase Inhibitory Properties of Optical Isomers and N-substituted Derivatives of 4-methylthioamphetamine 
      Hurtado Guzmán, Claudio; Fierro, Angélica; Iturriaga-Vásquez, Patricio; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Reyes Parada, Miguel (Taylor & Francis Ltd, 2003-03-10)
      (6)-4-Methylthioamphetamine (MTA) was resolved into its enantiomers, and a series of N-alkyl derivatives of the parent compound, as well as its a-ethyl analogue, were prepared. The monoamine oxidase (MAO) inhibitory properties ...
    • S-OXIDATION PRODUCTS OF ALKYLTHIOAMPHETAMINES 
      Caroli Rezende, Marcos; Núñez, Christián; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Hurtado Guzmán, Claudio (Marcel Dekker, Inc., 2001-09-18)
      The preparation of the sulfoxides and the sulfones of two centrally active alkylthioamphetamine salts, ( )-1-(4-methylthiophenyl)- 2-aminopropane hydrochloride (2) (MTA HCl) and ( )-1-(2,5-dimethoxy-4-ethylthiophenyl ...