Browsing by Author "Lois, Pablo"

Now showing items 1-4 of 4

    • Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source 
      Martínez, Constanza; Cornejo, Víctor Hugo; Lois, Pablo; Ellis, Tammy; Solis, Natalia P.; Wainwright, Brandon J.; Palma Alvarado, Verónica (PLoS ONE, 2013)
      The Sonic Hedgehog (Shh) pathway is responsible for critical patterning events early in development and for regulating the delicate balance between proliferation and differentiation in the developing and adult vertebrate ...
    • Shh Signaling through the Primary Cilium Modulates Rat Oligodendrocyte Differentiation 
      Falcón Urrutia, Paulina; Carrasco, Carlos M.; Lois, Pablo; Palma, Verónica; Roth Metcalfe, Alejandro Darío (Public Library Science, 2015)
      Primary Cilia (PC) are a very likely place for signal integration where multiple signaling pathways converge. Two major signaling pathways clearly shown to signal through the PC, Sonic Hedgehog (Shh) and PDGF-Ra, are ...
    • Sonic Hedgehog modulates EGFR dependent proliferation of neural stem cells during late mouse embryogenesis ... 
      Reinchisi, Gisela; Parada, Margarita; Lois, Pablo; Oyanadel, Claudia; Shaughnessy, Ronan; Gonzalez, Alfonso; Palma Alvarado, Verónica (2013-09)
      Sonic Hedgehog (Shh/GLI) and EGFR signaling pathways modulate Neural Stem Cell (NSC) proliferation. How these signals cooperate is therefore critical for understanding normal brain development and function. Here we report ...
    • The Netrin-1-Neogenin-1 signaling axis controls neuroblastoma cell migration via integrin-beta 1 and focal ... 
      Villanueva, Andrea A.; Sánchez Gómez, Pilar; Muñoz Palma, Ernesto Fabián; Puvogel Vittini, Sofía; Casas, Bárbara S.; Arriagada, Cecilia; Peña Villalobos, Isaac Jonathan; Lois, Pablo; Ramírez Orellana, Manuel; Lubieniecki, Fabiana; Casco Claro, Fernando; Gallegos, Iván; García Castro, Javier; Torres, Vicente A.; Palma Alvarado, Verónica Alejandra (Taylor & Francis, 2021)
      Neuroblastoma is a highly metastatic tumor that emerges from neural crest cell progenitors. Focal Adhesion Kinase (FAK) is a regulator of cell migration that binds to the receptor Neogenin-1 and is upregulated in ...