Browsing by Author "Loyola, Alejandra"

Now showing items 1-2 of 2

    • The demethylase inhibitor GSK‑J4 limits infammatory colitis by promoting de novo synthesis of retinoic acid ... 
      Doñas, Cristian; Neira, Jocelyn; Osorio Barrios, Francisco; Carrasco, Macarena; Fernández, Dominique; Prado, Carolina; Loyola, Alejandra; Pacheco, Rodrigo; Rosemblatt Silber, Mario César (Nature, 2021)
      Dendritic cells (DCs) promote T-cell mediated tolerance to self-antigens and induce inflammation to innocuous-antigens. This dual potential makes DCs fundamental players in inflammatory disorders. Evidence from inflammatory ...
    • Trichostatin A Promotes the Generation and Suppressive Functions of Regulatory T Cells 
      Doñas, Cristian; Fritz, Macarena; Manríquez, Valeria; Tejón, Gabriela; Bono Merino, María Rosa; Loyola, Alejandra; Rosemblatt Silber, Mario César (Hindawi, 2013)
      Regulatory T cells are a specific subset of lymphocytes that suppress immune responses and play a crucial role in the maintenance of self-tolerance. They can be generated in the thymus as well as in the periphery through ...