Browsing by Author "Mena, Natalia"

Now showing items 1-5 of 5

    • A selective fluorescent probe for the detection of mercury (II) in aqueous media and its applications in ... 
      García Beltrán, Olimpo; Mena, Natalia; Berríos, Tania A.; Castro, Enrique A.; Cassels Niven, Bruce; Núñez González, Marco; Aliaga, Margarita E. (2012)
      In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl) propyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (PMR), which can reversibly detect mercuric ions (Hg 2+) in HEPES buffer under physiological ...
    • Design and synthesis of a new coumarin-based 'turn-on' fluorescent probe selective for Cu +2 
      García Beltrán, Olimpo; Mena, Natalia; Friedrich, Leidi C.; Netto-Ferreira, José Carlos; Vargas, Víctor; Quina, Frank H.; Núñez González, Marco; Cassels Niven, Bruce (2012)
      The novel coumarin-based 'turn-on' fluorescent probe (E)-3-(2,5- dimethoxybenzylideneamino)-7-hydroxy-2H-chromen-2-one (MGM) was designed, synthesized, and characterized. This compound shows high selectivity for Cu +2, ...
    • Design, synthesis and cellular dynamics studies in membranes of a new coumarin-based "turn-off" fluorescent ... 
      García Beltrán, Olimpo; Mena, Natalia; Yañez, Osvaldo; Caballero, Julio; Vargas, Víctor; Núñez González, Marco; Cassels Niven, Bruce (Elsevier Masson SAS, 2013)
      A new coumarin-based 'turn-off' fluorescent probe, 7-(diethylamino)-N-(1,3- dihydroxy-2-(hydroxymethyl) propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ions ...
    • Iron homeostasis in neuronal cells: A role for IREG1 
      Aguirre, Pabla; Mena, Natalia; Tapia, Victoria; Arredondo, Miguel; Núñez González, Marco (2005)
      Background: Iron is necessary for neuronal function but in excess generates neurodegeneration. Although most of the components of the iron homeostasis machinery have been described in neurons, little is known about the ...
    • Iron toxicity in neurodegeneration 
      Núñez González, Marco; Urrutia, Pamela J.; Mena, Natalia; Aguirre, Pabla; Tapia, Victoria; Salazar, Julio (2012)
      Iron is an essential element for life on earth, participating in a plethora of cellular processes where one-electron transfer reactions are required. Its essentiality, coupled to its scarcity in aqueous oxidative environments, ...