Browsing by Author "Rosenman, Eduardo"

Now showing items 1-3 of 3

    • Deletion of the S3-S4 linker in the Shaker potassium channel reveals two quenching groups near the outside of S4 
      Sorensen, J. B.; Cha, A.; Latorre, Ramón; Rosenman, Eduardo; Bezanilla, Francisco (ROCKEFELLER UNIV PRESS, 2000-02)
      When attached outside the voltage-sensing S4 segment of the Shaker potassium channel, the fluorescent probe tetramethylrhodamine (TMRM) undergoes voltage-dependent fluorescence changes (Delta F) due to differential interaction ...
    • Modulation of the Shaker K+ channel gating kinetics by the S3-S4 linker 
      González, Carlos; Rosenman, Eduardo; Bezanilla, Francisco; Álvarez Araya, Osvaldo; Latorre, Ramón (ROCKEFELLER UNIV PRESS, 2000-02)
      In Shaker K+ channels depolarization displaces outwardly the positively charged residues of the S4 segment. The amount of this displacement is unknown, but large movements of the S4 segment should be con strained by the ...
    • Periodic perturbations in Shaker K+ channel gating kinetics by deletions in the S3-S4 linker 
      González, Carlos; Rosenman, Eduardo; Bezanilla, Francisco; Álvarez Araya, Osvaldo; Latorre, Ramón (NATL ACAD SCIENCES, 2001-08-14)
      Upon depolarization positive charges contained in the transmembrane segment S4 of voltage-dependent channels are displaced from the cytoplasmic to the external milieu, This charge movement leads to channel opening. In ...