Now showing items 1-4 of 4

    • Moore, Carolina; Tejón, Gabriela; Fuentes, Camila; Hidalgo, Yessia; Bono Merino, María Rosa; Maldonado, Paula; Fernández, Ricardo; Wood, Kathryn; Fierro, Juan; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela; Bushell, Andrew (Wiley-Blackwell, 2015)
      CD4+CD25+Foxp3+ regulatory T (Treg) cells mediate immunological self-tolerance and suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has been reported to enhance the differentiation of ...
    • Flores Santibáñez, Felipe; Fernández, Dominique; Meza, Daniel; Tejón, Gabriela; Vargas, Leonardo; Varela Nallar, Lorena; Arredondo, Sebastián; Guixé Leguía, Victoria Cristina; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; Sauma Mahaluf, Daniela (Wiley & Sons, 2015)
      The CD73 ectonucleotidase catalyses the hydrolysis of AMP to adenosine, an immunosuppressive molecule. Recent evidence has demonstrated that this ectonucleotidase is up-regulated in T helper type 17 cells when generated in ...
    • Nuñez, Sarah; Saez, Juan José; Fernández, Dominique; Flores Santibañez, Felipe; Álvarez, Karla; Tejón, Gabriela; Ruiz, Paulina; Maldonado, Paula; Hidalgo, Yessia; Manriquez, Valeria; Bono Merino, María Rosa; Rosemblatt Silber, Mario César; Sauma Mahaluf, Daniela (Blackwell Publishing, 2013)
      T helper type 17 (Th17) lymphocytes are found in high frequency in tumour-burdened animals and cancer patients. These lymphocytes, characterized by the production of interleukin-17 and other pro-inflammatory cytokines, ...
    • Doñas, Cristian; Fritz, Macarena; Manríquez, Valeria; Tejón, Gabriela; Bono Merino, María Rosa; Loyola, Alejandra; Rosemblatt Silber, Mario César (Hindawi, 2013)
      Regulatory T cells are a specific subset of lymphocytes that suppress immune responses and play a crucial role in the maintenance of self-tolerance. They can be generated in the thymus as well as in the periphery through ...