Browsing by Author "Utreras Puratich, Elías"

Now showing items 1-6 of 6

    • Conditional TNF-alpha Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis 
      Hall, B.E.; Zhang, L.; Sun, Z. J.; Utreras Puratich, Elías; Prochazkova, M.; Cho, A.; Terse, A.; Arany, P.; Dolan, J. C.; Schmidt, B. L.; Kulkarni, A. B. (International & American Associations for Dental Research, 2016)
      Tumor necrosis factor-alpha(TNF-alpha) is a proalgesic cytokine that is commonly expressed following tissue injury. TNF-alpha expression not only promotes inflammation but can also lead to pain hypersensitivity in nociceptors. ...
    • Conditional TNF-α Overexpression in the Tooth and Alveolar Bone Results in Painful Pulpitis and Osteitis 
      Hall, B. E.; Zhang, L.; Sun, Z. J.; Utreras Puratich, Elías; Prochazkova, M.; Cho, A.; Terse, A.; Arany, P.; Dolan, J. C.; Schmidt, B. L.; Kulkarni, A. B. (SAGE Publications Inc., 2016)
      © International & American Associations for Dental Research 2015. Tumor necrosis factor-α (TNF-α) is a proalgesic cytokine that is commonly expressed following tissue injury. TNF-α expression not only promotes inflammation ...
    • Going out of the brain: Non-nervous system physiological and pathological functions of Cdk5 
      Contreras Vallejos, Erick; Utreras Puratich, Elías; González Billault, Christian (Elsevier, 2012)
      Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase that is mostly active in the nervous system, where it regulates several processes such as neuronal migration, actin and microtubule dynamics, axonal ...
    • Microtubule-associated protein 1B interaction with tubulin tyrosine ligase contributes to the control of ... 
      Utreras Puratich, Elías; Jiménez Mateos, Eva Maria; Contreras Vallejos, Erick; Tortosa, Elena; Pérez, Mar; Rojas, Sebastián; Saragoni, Lorena; Maccioni Baraona, Ricardo; Avila, Jesús; González Billault, Christian (2007)
      Microtubule-associated protein 1B (MAP1B) is the first microtubule- associated protein to be expressed during nervous system development. MAP1B belongs to a large family of proteins that contribute to the stabilization ...
    • Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5 -/- Mice 
      Contreras Vallejos, Erick; Utreras Puratich, Elías; Bórquez Muñoz, Daniel; Prochazkova, Michaela; Terse, Anita; Jaffe, Howard; Toledo, Andrea; Arruti, Cristina; Pant, Harish C.; Kulkarni, Ashok B.; González Billault, Christian (2014)
      Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly ...
    • TNF-α increases production of reactive oxygen species through Cdk5 activation in nociceptive neurons 
      Sandoval Guzmán, Rodrigo; Lazcano Sánchez, Pablo; Ferrari Soto, Franco; Pinto Pardo, Nicolás; González Billault, Christian; Utreras Puratich, Elías (Frontiers Media, 2018)
      The participation of reactive oxygen species (ROS) generated by NOX1 and NOX2/NADPH oxidase has been documented during inflammatory pain. However, the molecular mechanism involved in their activation is not fully understood. ...