Browsing by Title Artículos de revistas

Now showing items 1418-1437 of 2801

    • Inkjet Printing of Proteins: an Experimental Approach 
      Montenegro-Nicolini, Miguel; Miranda, Víctor; Morales, Javier O. (Springer New York LLC, 2017)
      © 2016, American Association of Pharmaceutical Scientists. Peptides and proteins represent a promissory group of molecules used by the pharmaceutical industry for drug therapy with great potential for development. However, ...
    • An Inositol 1,4,5-Triphosphate (IP3)-IP3 Receptor Pathway Is Required for Insulin-Stimulated Glucose ... 
      Contreras Ferrat, Ariel Eduardo; Toro, Barbra; Bravo, R.; Parra Ortíz, María Valentina; Vásquez, C.; Ibarra, Cristián; Mears, David; Chiong Lay, Mario; Jaimovich Pérez, Enrique; Klip, Amira; Lavandero González, Sergio (ENDOCRINE SOC, 2010-10)
      Intracellular calcium levels ([Ca2+](i)) and glucose uptake are central to cardiomyocyte physiology, yet connections between them have not been studied. We investigated whether insulin regulates [Ca2+](i) in cultured ...
    • The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 
      Vicencio, José Miguel; Ortíz, C.; Criollo Céspedes, Alfredo; Jones, A. W. E.; Kepp, O.; Galluzzi, Lorenzo; Joza, N.; Vitale, I.; Morselli, E.; Tailler, M.; Castedo, M.; Maiuri, M. C.; Molgó, Jordi; Szabadkai, G.; Lavandero González, Sergio; Kroemer, Guido (NATURE PUBLISHING GROUP, 2009-07)
      The inositol 1,4,5-trisphosphate receptor (IP3R) is a major regulator of apoptotic signaling. Through interactions with members of the Bcl-2 family of proteins, it drives calcium (Ca2+) transients from the endoplasmic ...
    • The inositol trisphosphate receptor in the control of autophagy 
      Criollo Céspedes, Alfredo; Vicencio, José Miguel; Tasdemir, E.; Maiuri, M. C.; Lavandero González, Sergio; Kroemer, Guido (LANDES BIOSCIENCE, 2007-07)
      The second messenger myo-inositol-1,4,5-trisphosphate (IP3) acts on the IP3 receptor (IP3R), an IP3-activated Ca2+ channel of the endoplasmic reticulum (ER). The IP3R agonist IP3 inhibits starvation-induced autophagy. The ...
    • Insights into the HyPer biosensor as molecular tool for monitoring cellular antioxidant capacity 
      Hernández, Helen; Parra, Alejandra; Tobar, Nicolas; Molina, Jessica; Kallens, Violeta; Hidalgo, Miltha; Varela, Diego; Martínez, Jorge; Porras Espinoza, Omar (Elsevier B.V., 2018)
      © 2018 The Authors Aerobic metabolism brings inexorably the production of reactive oxygen species (ROS), which are counterbalanced by intrinsic antioxidant defenses avoiding deleterious intracellular effects. Redox balance ...
    • Insights of the formation mechanism of nanostructured titanium oxide polymorphs from different macromolecular ... 
      Allende, Patricio; Orera, Alodia; Laguna Bercero, Miguel A.; Valenzuela, María Luisa; Díaz, Carlos; Barrientos, Lorena (Elsevier, 2021)
      The insight into the mechanism of the unprecedented formation of pure anatase TiO2 from the macromolecular (Chitosan)center dot(TiOSO4)(n) precursor has been investigated using micro Raman spectroscopy, Scanning Electron ...
    • Insulin receptor isoforms: an integrated view focused on gestational diabetes mellitus 
      Westermeier, Francisco; Sáez, T.; Arroyo, P.; Toledo, F.; Gutiérrez, J.; Sanhueza, C.; Pardo, F.; Leiva, A.; Sobrevia, L. (Wiley-Blackwell, 2016)
      The human insulin receptor (IR) exists in two isoforms that differ by the absence (IR-A) or the presence (IR-B) of a 12-amino acid segment encoded by exon 11. Both isoforms are functionally distinct regarding their binding ...
    • Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes-reduced ... 
      Westermeier, Francisco; Salomón, Carlos; Farías, Marcelo; Arroyo, Pablo; Fuenzalida, Bárbara; Sáez, Tamara; Salsoso, Rocío; Sanhueza, Carlos; Guzmán Gutiérrez, Enrique; Pardo, Fabián; Leiva, Andrea; Sobrevia, Luis (2015)
      Reduced adenosine uptake via human equilibrative nucleoside transporter 1 (hENT1) in human umbilical vein endothelial cells (HUVECs) from gestational diabetes mellitus (GDM) is reversed by insulin by restoring hENT1 ...
    • Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death 
      Díaz, Ariel; Humeres, Claudio; González, Verónica; Gómez, María Teresa; Montt, Natalia; Sánchez, Gina; Chiong Lay, Mario; García Nannig, Lorena (Academic Press Inc., 2015)
      In the heart, insulin controls key functions such as metabolism, muscle contraction and cell death. However, all studies have been focused on insulin action during reperfusion. Here we explore the cardioprotective action ...
    • INTEGRATED FIA HPLC METHOD FOR PRECONCENTRATION AND DETERMINATION OF TRANSITION-METAL IONS 
      Fernández Romero, J. M.; De Castro, M. D. L.; Richter Duk, Pablo; Valcarcel, Miguel (FRIEDR VIEWEG SOHN VERLAG GMBH, 1992-11)
      An automatic method based on the combination of a flow injection (FI) manifold with a liquid chromatograph has been developed for the enrichment and determination of transition metal ions in water samples. Alternatively, ...
    • Integrated Pressurized Solvent Extraction-Cleanup for the Rapid Determination of Polychlorinated Biphenyls ... 
      Toledo Neira, Carla; Enríquez, Pedro; Richter Duk, Pablo (Sociedade Brasileira de Química, 2013)
      A rapid and efficient method based on the integration of pressurized solvent extraction (PSE) with solid phase extraction (SPE) cleanup and gas chromatography system with electron capture detection (GC-ECD) has been developed ...
    • Integrated retention/spectrophotometric detection method for the determination of formaldehyde 
      Richter Duk, Pablo; Luque de Castro, M.; Valcárcel, Miguel (1992)
      An integrated-sensor method for the determination of formaldehyde based on retention of the reaction product of the analyte with p-rosaniline and sulfite in a flow-cell packed with Dowex 1-X-8 anion exchange resin was ...
    • Integrated sulfate reduction and biosorption process for the treatment of mine drainages 
      Cotoras, Davor; Hurtado, Cristian; Viedma, Pabla (Trans Tech, 2017)
      Sulfate is a pollutant present in the mining waste water and acid mine drainage. High levels of sulfate can generate important environmental problems. One of the alternatives proposed for the treatment of water with high ...
    • Integration of Community pharmacy and pharmacists in primary health care policies in Argentina 
      Armando, Pedro D.; Uema, Sonia A.; Vega, Elena (Centro Investigaciones & Publicaciones Farmacéuticas, España, 2020)
      Argentina is a federal republic with approximately 44 million people, divided into 23 provinces and an autonomous city, Buenos Aires. The health system is segmented into public, social security and private subsystems. The ...
    • Intense White Molecular Fluorescence from Naphthoxazole-Quinoline Derivatives 
      Zanocco, Renzo P.; Valdebenito, Silvana; Gidi, Yasser; Zapata Torres, Gerald; Lemp Miranda, Else; Nonell, Santi; Zanocco Loyola, Antonio (Blackwell Publishing Inc., 2018)
      © 2018 The American Society of Photobiology Naphthoxazole derivatives are small heterocyclic compounds endowed with outstanding fluorescence properties. In this work, we report a detailed study of the intense white light ...
    • Interaction between glutathione and ampicillin: an a.c. polarographic method 
      Squella Serrano, Juan; Núñez Vergara, Luis (1983)
      The interaction of glutathione with ampicillin was investigated by a new a.c. polarographic procedure. Ampicillin was found to interact strongly with glutathione. The stability constants were ascertained from the polarographic ...
    • Interaction of 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (dimboa) with alcoholic solvents 
      Bravo, Héctor R.; Niemeyer, Hermann M. (1986)
      Solubilities and IR spectra of DIMBOA in alcoholic solvents showed that the carbonyl group of DIMBOA is hydrogen-bonded to the solvent. Activation parameters of DIMBOA in the same solvents suggested that the decomposition ...
    • Interaction of 5-aminosalicylic acid with nitrous acid: Formation of the diazonium derivative and nitric ... 
      López Alarcón, Camilo; Lissi, E.; Hoffmann, P.; Mella, J.; Pessoa Mahana, Carlos David; Speisky Cosoy, Hernán; Möller, M.; Ferrer-Sueta, G.; Denicola, A. (2011)
      The reaction of 5-aminosalicylic acid (5-ASA) with nitrous acid has been studied at low pH under conditions that simulate a gastric environment. The course of the reaction was followed by UV-visible and fluorescence ...
    • Interactions between analgesics and calcium channel blockers 
      Miranda, H.; Paeile, C. (1990)
      1. The findings, derived from different experimental models, examined in this review, provide evidence that the calcium channel blockers and related drugs possess analgesic effects. 2. The antinociceptive action that some ...
    • Interest of antioxidant agents in parasitic diseases. The case study of coumarins 
      Figueroa-Guiñez, Roberto; Matos, Maria João; Vazquez Rodriguez, Saleta; Santana, Lourdes; Uriarte, Eugenio; Borges, Fernanda; Olea Azar, Claudio; Maya Arango, Juan (Bentham Science Publishers B.V., 2015)
      © 2015 Bentham Science Publishers. Tropical parasitic diseases, especially those produced by protozoan parasites, are a major public health problem in many countries, and their impact in the health burden is significant. ...