Browsing by Title Artículos de revistas

Now showing items 11023-11042 of 11554

    • Trofoblasto, impronta y conflicto genómico en Gineco-Obstetricia 
      Bustos Vidal, Juan (2015)
      La teoría del Conflicto Genómico es parte de la biología evolutiva y actúa en los mamíferos a través del mecanismo de impronta genética, estos genes cumplen un rol central en el desarrollo fetal y del trofoblasto contribuyendo ...
    • Tromboembolismo pulmonar masivo con respuesta exitosa a trombolisis farmacológica. Caso clínico 
      Leal, José Luis; Lora, Pilar; Enciso, Giovanni; Reynolds, Enrique (SOC MEDICA SANTIAGO, 2010-07)
      Massive pulmonary thromboembolism has a high mortality. Early thrombolysis is the treatment of choice. We report a 79-year-old man admitted in shock. A chest angio-CAT scan showed a massive pulmonary thromboembolism. A ...
    • Trombolisis cerebral en el adulto mayor. Caso clínico 
      Reccius, Andrés; Illanes Diez, Sergio; Jaramillo, Arturo; Manterola, José Luis; Díaz Tapia, Violeta (SOC MEDICA SANTIAGO, 2008-04)
      Most studies evaluating the usefulness of intravenous thrombolysis for acute stroke have excluded subjects aged over 80 years. Therefore there is no evidence to support or contraindicate this therapy in this age group. ...
    • Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: ... 
      Guevara O., Carlos; Bulatova, Kateryna; Aravena, Felipe; Caba, Sheila; Monsalve, Juan; Lara, Hugo; Nieto, Elena; Navarrete, Isabel; Morales, Marcelo (Soc Médica Santiago, 2016)
      Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) reduces disability in patients with ischemic stroke. However, its implementation in Chilean public general hospitals has been ...
    • Trophoblast turnover in human placental chorionic villi explants induced by trypanosoma cruzi is mediated ... 
      Castillo, Christian; Muñoz, Lorena; Carrillo, Ileana; Droguett, Daniel; Liempi, Ana; Astudillo, Javier; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Congenital Chagas’ disease, caused by the protozoan Trypanosoma cruzi (T. cruzi), is one of the major public health concerns in Latin America where more than one million women in fertile age are infected. During ...
    • TRP channels interactome as a novel therapeutic target in breast cancer 
      Saldías Maulén, María Paz; Maureira Fuentes, Diego Javier; Orellana Serradell, Octavio Andrés; Silva del Canto, Ian; Lavanderos Andrade, Boris Joan; Cruz, Pablo; Torres Paredes, Camila Esperanza; Cáceres Lluch, Mónica; Cerda Arancibia, Oscar Alejandro (MDPI, 2021)
      Breast cancer is one of the most frequent cancer types worldwide and the first cause of cancer-related deaths in women. Although significant therapeutic advances have been achieved with drugs such as tamoxifen and trastuzumab, ...
    • TRP channels regulation of Rho GTPases in brain context and diseases 
      Lavanderos, Boris; Silva, Ian; Cruz, Pablo; Orellana Serradell, Octavio; Saldías, María Paz; Cerda Arancibia, Óscar (Frontiers Media, 2020)
      Neurological and neuropsychiatric disorders are mediated by several pathophysiological mechanisms, including developmental and degenerative abnormalities caused primarily by disturbances in cell migration, structural ...
    • TRP, TRPL and Cacophony Channels Mediate Ca2+ Influx and Exocytosis in Photoreceptors Axons in Drosophila 
      Astorga, Guadalupe; Härtel, Steffen; Sanhueza, Magdalena; Bacigalupo Vicuña, Juan (2012)
      In Drosophila photoreceptors Ca2+-permeable channels TRP and TRPL are the targets of phototransduction, occurring in photosensitive microvilli and mediated by a phospholipase C (PLC) pathway. Using a novel Drosophila brain ...
    • TRPM Channels in Human Diseases 
      Jiménez, Ivanka; Prado, Yolanda; Marchant, Felipe; Otero, Carolina; Eltit, Felipe; Cabello Verrugio, Claudio; Cerda Arancibia, Óscar; Simón, Felipe (MDPI, 2020)
      The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been made in identifying novel members of the TRPM ...
    • TRPM4 activation by chemically- and oxygen deprivation-induced ischemia and reperfusion triggers neuronal death 
      Leiva Salcedo, Elias; Riquelme, Denise; Cerda Arancibia, Óscar; Stutzin Schottlander, Andrés (Taylor & Francis, 2017)
      Cerebral ischemia-reperfusion injury triggers a deleterious process ending in neuronal death. This process has two components, a glutamate-dependent and a glutamate-independent mechanism. In the glutamate-independent ...
    • TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of ... 
      Sagredo, Alfredo I.; Sagredo, Eduardo A.; Pola, Victor; Echeverría, César; Andaur, Rodrigo; Michea Acevedo, Luis; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisén, Ricardo (Wiley, 2019)
      Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐ dependent monovalent cation channel, which depolarizes the plasma cell membrane, thereby modulating Ca2+ influx across Ca2+‐permeable ...
    • TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway 
      Armisen Yáñez, Ricardo; Marcelain Cubillos, Katherine; Simon, Felipe; Tapia, Julio C.; Toro, Jessica; Quest, Andrew F. G.; Stutzin Schottlander, Andrés (2011)
      Altered expression of some members of the TRP ion channel superfamily has been associated with the development of pathologies like cancer. In particular, TRPM4 levels are reportedly elevated in diffuse large B-cell non-Hodgkin ...
    • TRPM4 Expression during postnatal developmental of mouse CA1 pyramidal neurons 
      Riquelme, Denise; Cerda Arancibia, Oscar Alejandro; Leiva Salcedo, Elías (Frontiers Media, 2021)
      TRPM4 is a non-selective cation channel activated by intracellular calcium and permeable to monovalent cations. This channel participates in the control of neuronal firing, neuronal plasticity, and neuronal death. TRPM4 ...
    • TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility 
      Cáceres Lluch, Mónica; Ortiz, Liliana; Recabarren, Tatiana; Romero, Aníbal; Colombo Flores, Alicia; Leiva Salcedo, Elías; Varela Lekanda, Diego; Rivas, José; Silva, Ian; Morales, Diego; Campusano, Camilo; Almarza, Óscar; Simon, Felipe; Toledo Araya, Héctor; Park, Kang-Sik; Trimmer, James S.; Cerda, Óscar (Public Library Science, 2015)
      Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca2+ oscillations. TRPM4 is a ...
    • TRPM4 regulates Akt/GSK3-b activity and enhances b-catenin signaling and cell proliferation in prostate ... 
      Sagredo, A.; Sagredo, Eduardo A.; Cappelli, Claudio; Baez, Pablo; Andaur, Rodrigo E.; Blanco, Constanza; Tapia, Julio C.; Echeverría, César; Cerda, Oscar; Stutzin Schottlander, Andrés; Simon, Felipe; Marcelain Cubillos, Katherine; Armisen Yáñez, Ricardo (John Wiley, 2018)
      Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing ...
    • TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia 
      Gatica, Sebastián; Villegas, Vicente; Vallejos, Alejandro; Olivares, Pedro; Aballai, Víctor; Lagos Meza, Felipe; Echeverría, César; Cabello Verrugio, Claudio; Varela Lekanda, Diego; Simón, Felipe (Nature Publishing Group, 2020)
      Acute kidney injury and endothelial hyperpermeability are main features observed during severe sepsis with low survival rate. Transient receptor potential melastatin 7 (TRPM7) calcium channel inhibition protects against ...
    • Truncating variants in UBAP1 associated with childhood-onset nonsyndromic hereditary spastic paraplegia 
      Gu, S; Chen, CA; Rosenfeld, JA; Cope, H; Launay, N; Flanigan, KM; Waldrop, MA; Schrader, R; Juusola, J; Goker-Alpan, O; Milunsky, A; Schluter, A; Troncoso, M; Pujol, A; Tan, QKG; Schaaf, CP; Meng, LY (John Wiley and Sons Inc.P.O.Box 18667NewarkNJ 07191-8667, 2020)
    • Tru‐cut and Menghini needles: different yield in the histological diagnosis of liver disease 
      Vargas Tank, Ling; Martinez, Nora; Jirón,; Soto, C.; Armas-Merino, Rodolfo (1985)
      ABSTRACT— An evaluation of the information obtained by percutaneous liver biopsy performed with Travenol Tru‐cut® (“Tru‐cut”), Menghini's 1.9 and 1.6 needles, was done using cadavers. All needles used had a similar, low ...
    • Trypanosoma cruzi and toxoplasma gondii induce a differential MicroRNA profile in human placental explants 
      Medina, Lisvaneth; Castillo Rivas, Christian; Liempi, Ana; Guerrero Muñoz, Jesús; Rojas Pirela, Maura; Maya Arango, Juan Diego; Prieto, Humberto; Kemmerling Weis, Ulrike (Frontiers Media, 2020)
      Trypanosoma cruzi and Toxoplasma gondii are two parasites than can be transmitted from mother to child through the placenta. However, congenital transmission rates are low for T. cruzi and high for T. gondii. Infection ...
    • Trypanosoma cruzi burden, genotypes, and clinical evaluation of Chilean patients with chronic Chagas cardiopathy 
      Apt Baruch, Werner; Arribada, Arturo; Zulantay Alfaro, Inés; Saavedra, Miguel; Araya, Eduardo; Solari Illescas, Aldo; Ortiz, Sylvia; Arriagada, Katherine; Sánchez Rodríguez, Jorge E. (Springer Verlag, 2015)
      © 2015, The Author(s).There are currently no biomarkers to assess which patients with chronic indeterminate Chagas disease will develop heart disease and which will spend their entire life in this state. We hypothetize ...