Now showing items 1470-1489 of 11550

    • Echiburú López, Bárbara; Pérez Bravo, Francisco; Maliqueo Yevilao, Manuel; Ladrón de Guevara, Amanda; Gálvez, Carla; Crisosto King, Nicolás; Sir Petermann, Teresa (2012)
      Background: The polycystic ovary syndrome (PCOS) is a hyperandrogenic disorder that arise from a combination of genetic and environmental factors. Aim: To assess the role of the androgen receptor (AR) CAG repeat polymorphism ...
    • Faundez, Gustavo; Troncoso, Miriam; Figueroa, Guillermo (BioMed Central Ltd., 2002)
      Background: The cytotoxin associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA) of Helicobacter pylori have been associated to phenotypic characteristics of virulence. The objectives of this study were to ...
    • Parra, Valentina; Rothermel, Beverly A. (Academic Press, 2017)
      © 2016 Elsevier LtdThe calcium-activated protein phosphatase, calcineurin, lies at the intersection of protein phosphorylation and calcium signaling cascades, where it provides an essential nodal point for coordination ...
    • Cano Schuffeneger, Francisco; Delucchi Bicocchi, María Angela; Wolff, Eduardo; Rodriguez, Eugenio; Fuentes, Angel (Springer-Verlag, 1995)
      A 6-month protocol of oral pulse calcitriol was used in nine uraemic children (2-14 years old) on dialysis who presented with renal osteodystrophy. Calcitriol was administered twice a week, 4 μg per dose for patients over ...
    • Carrasco, Fernando; Basfi-fer Obregón, Karen; Rojas, Pamela; Csendes Juhasz, Attila; Papapietro Vallejo, Karin; Codoceo, Juana; Inostroza, Jorge; Krebs, Nancy; Westcott, Jamie; Miller, Leland; Ruz Ortiz, Manuel (Oxford University Press, 2018)
      Background: Although Roux-en-Y gastric bypass (RYGBP) is known to reduce calcium absorption (CA), the effects of vertical sleeve gastrectomy (SG) and its long-term implications on CA have not yet been studied. Objective: ...
    • Soto, Claudio; Rodríguez, Patricio H.; Monasterio Opazo, Octavio (1996)
      Ca2+ and Gd3+ stimulated the GTPase activity of chicken brain tubulin 13- and 26-fold, respectively. Mg2+, Tb3+, and Na+ had no effect. This GTPase activity showed a saturation behavior with Ca2+ and Gd3+ with a maximal ...
    • Ardiles, Alvaro O.; González-Jamett, Arlek M.; Maripillán, Jaime; Naranjo, David; Caviedes, Pablo; Cárdenas, Ana María (2007)
      Various studies have focused in the relative contribution of different voltage-activated Ca2+ channels (VACC) to total transmitter release. However, how Ca2+ entry through a given VACC subtype defines the pattern of ...
    • Marengo Olivares, Juan José; Bull Simpfendorfer, Ricardo; Hidalgo Tapia, María Cecilia (Elsevier B.V., 1996)
      Endoplasmic reticulum vesicles isolated from rat brain cortex and fused with lipid bilayers displayed ryanodine-sensitive calcium channels, with three cytoplasmic calcium dependences. A: Channels (n = 5) stimulated by Ca2+ ...
    • Gaitán, Diego; Flores, Sebastián; Saavedra, Pía; Miranda, Constanza; Olivares, Manuel; Arredondo, Miguel; López de Romaña, Daniel; Lönnerdal, Bo; Pizarro Aguirre, Fernando (2011)
      Calcium is the only known component in the diet that may affect absorption of both nonheme and heme iron. However, the evidence for a calcium effect on iron absorption mainly comes from studies that did not isolate the ...
    • Caviedes, Pablo; Olivares, Enrique; Salas, Karime; Caviedes, Raúl; Jaimovich Pérez, Enrique (1993)
      A cell line (RCVC) in permanent culture was developed from adult rat ventricular cells; transformation was attained by incubation with conditioned media from UCHTI, a rat thyroid cell line. Immortalized ventricular cells ...
    • Carrasco Friz, María Angélica; Hidalgo Tapia, María Cecilia (CHURCHILL LIVINGSTONE, 2006-12)
      Neurons generate particular calcium microdomains in response to different stimuli. Calcium microdomains have a central role in a variety of neuronal functions. In particular, calcium microdomains participate in long-lasting ...
    • Kemmerling Weis, Ulrike; Muñoz Dimitrov, Pablo; Müller, Marioly; Sánchez, Gina; Aylwin Ostale, María de la Luz; Klann, Eric; Carrasco Friz, María Angélica; Hidalgo Tapia, María Cecilia (2007)
      Hydrogen peroxide, which stimulates ERK phosphorylation and synaptic plasticity in hippocampal neurons, has also been shown to stimulate calcium release in muscle cells by promoting ryanodine receptor redox modification ...
    • More, Jamileth Y.; Bruna, Barbara A.; Lobos, Pedro; Galaz, Jose L.; Figueroa, Paula L.; Namias, Silvia; Sánchez, Gina; Barrientos Briones, Genaro; Valdes Guerrero, Jose; Paula Lima, Andrea; Hidalgo Tapia, María Cecilia; Adasme, Tatiana (Mary Ann Liebert Inc publishers, 2018)
      Aims: Previous studies indicate that hippocampal synaptic plasticity and spatial memory processes entail calcium release from intracellular stores mediated by ryanodine receptor (RyR) channels. In particular, RyR-mediated ...
    • Rojas, Cecilia V.; Jaimovich Pérez, Enrique (Springer-Verlag, 1990)
      To investigate the effect of inositol 1,4,5-trisphosphate on calcium release, we used fiber bundles of frog sartorius muscle mechanically permeabilized by a scratching procedure, and we detected increments in calcium ...
    • Hidalgo Tapia, María Cecilia (Lippincott Williams and Wilkins, 2017)
    • Carreras Sureda, Amado; Pihan, Philippe; Hetz Flores, Claudio (Elsevier, 2018)
      Endoplasmic reticulum (ER) calcium signaling is implicated in a myriad of coordinated cellular processes. The ER calcium content is tightly regulated as it allows a favorable environment for protein folding, in addition ...
    • Contreras Ferrat, Ariel Eduardo; Lavandero González, Sergio; Jaimovich Pérez, Enrique; Klip, Amira (Churchill Livingstone, 2014)
      © 2014 Elsevier Ltd. Striated muscles (skeletal and cardiac) are major physiological targets of insulin and this hormone triggers complex signaling pathways regulating cell growth and energy metabolism. Insulin increases ...
    • Estrada Hormazábal, Manuel; Cárdenas Matus, Julio; Liberona Leppe, José; Carrasco, María Angélica; Mignery, Gregory A.; Allen, Paul D.; Jaimovich Pérez, Enrique (Amer Soc Biochemistry Molecular Biology, 2001)
      Potassium depolarization of skeletal myotubes evokes slow calcium waves that are unrelated to contraction and involve the cell nucleus (Jaimovich, E., Reyes, R., Liberona, J. L., and Powell, J. A. (2000) Am. J. Physiol. ...
    • Hidalgo Tapia, María Cecilia; Núñez González, Marco (2007)
      Calcium and iron play dual roles in neuronal function: they are both essential but when present in excess they cause neuronal damage and may even induce neuronal death. Calcium signals are required for synaptic plasticity, ...
    • Hidalgo Tapia, María Cecilia; Arias Cavieres, Alejandra (American Physiological Society, 2016-05)
      In this review article, we address how activity-dependent Ca2+ signaling is crucial for hippocampal synaptic/structural plasticity and discuss how changes in neuronal oxidative state affect Ca2+ signaling and synaptic ...