Now showing items 1261-1280 of 11593

    • Pérez, Federico; Ruera, Carolina N.; Miculan, Emanuel; Carasi, Paula; Dubois Camacho, Karen; Garbi, Laura; Guzmán, Luciana; Hermoso, Marcela; Chirdo, Fernando G. (Frontiers Media, 2020)
      Initially described as Th2 promoter cytokine, more recently, IL-33 has been recognized as an alarmin, mainly in epithelial and endothelial cells. While localized in the nucleus acting as a gene regulator, it can be also ...
    • Aguayo González, Francisco; Muñoz, Juan P.; Pérez Domínguez, Francisco; Carrillo Beltrán, Diego; Estibaliz Oliva, Carolina; Calaf, Gloria M.; Blanco, Rances; Núñez Acurio, Daniela (MDPI, 2020)
      Cervical, anogenital, and some head and neck cancers (HNC) are etiologically associated with high-risk human papillomavirus (HR-HPV) infection, even though additional cofactors are necessary. Epidemiological studies have ...
    • Núñez Figueroa, Paulina; Sedano, Rocío; Quera, Rodrigo; Carrasco Avino, Gonzalo; O'Brien, Andrés; Brahm, Javier (Aran Ediciones, 2020)
      La enfermedad inflamatoria intestinal (EII) se relaciona con distintas manifestaciones hepáticas como compromiso extraintestinal; la colangitis esclerosante primaria (CEP) es la más frecuente de ellas. Durante su ...
    • Leive, Lorena; Morrison Jara, Rodolfo (Cuba Editora, 2020)
      Sleep occupation bears interesting and particular characteristics when described from the occupational science perspective. This theoretical essay examines literature from different disciplines, as well as key concepts of ...
    • Vilugrón Aravena, Fabiola; Molina González, Temístocles; Gras Pérez, María Eugenia; Font Mayolas, Silvia (Sociedad Médica de Santiago, 2020)
      Background: Adolescence is considered a nutritionally vulnerable period of life, since their eating habits are influenced by factors that can promote the consumption of non-nutritious food. Aim: To analyze the relation ...
    • Arellano Lorca, Javier; Álvarez, Danae; Salinas, María Paz; Molina, Ilma (Sociedad Médica de Santiago, 2020)
      Background: Stevens-Johnson Syndrome (SSJ) and Toxic Epidermal Necrolysis (NET) are infrequent and life-threatening mucocutaneous diseases, which occur predominantly as adverse drug reactions. Aim: To describe the frequency ...
    • Tittarelli, Andrés; Navarrete, Mariela; Lizana, Marcelo; Hofmann Vega, Francisca; Salazar Onfray, Flavio (MDPI, 2020)
      Alterations in microRNA (miRNA) profiles, induced by tumor microenvironment stressors, like hypoxia, allow cancer cells to acquire immune-resistance phenotypes. Indeed, hypoxia-induced miRNAs have been implicated in cancer ...
    • Farfán, Nancy; Carril, Jaime; Redel, Martina; Zamorano, Marta; Araya, Maureen; Monzón, Estephania; Alvarado, Raúl; Contreras, Norton; Tapia Bustos, Andrea; Quintanilla González, María; Ezquer, Fernando; Valdés, José Luis; Israel Jacard, Yedy; Herrera Marschitz, Mario; Morales Retamales, Eugenia (2020)
      Perinatal Asphyxia (PA) is a leading cause of motor and neuropsychiatric disability associated with sustained oxidative stress, neuroinflammation, and cell death, affecting brain development. Based on a rat model of global ...
    • Canales, Jimena; Cruz, Pablo; Villacura Díaz, Nicolás Esteban; Riquelme, Denise; Leiva Salcedo, Elias; Cerda Arancibia, Óscar (MDPI, 2020)
      Cell migration is critical for several physiological and pathophysiological processes. It depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and Ca2+ signaling. Interestingly, ubiquitination ...
    • Braghetto, Italo; Figueroa-Giralt, Manuel (Springer, 2020)
      A wide spectrum of research such as experimental, randomized trials, cohort or epidemiological studies, technical or control case reports, systematic reviews, and meta-analyses has resulted in a huge amount of publications. ...
    • Garrido Palma, Maritza; Salvatierra, Renato; Valenzuela Valderrama, Manuel; Vallejos, Christopher; Bruneau, Nicole; Hernández, Andrea; Vega Blanco, María Margarita; Selman Abuchaibe, Alberto; Geoffery Quest, Andrew; Romero Osses, Carmen (MDPI, 2020)
      Epithelial ovarian cancer (EOC) is a lethal gynaecological neoplasm characterized by rapid growth and angiogenesis. Nerve growth factor (NGF) and its high affinity receptor tropomyosin receptor kinase A (TRKA) contribute ...
    • Dassonvalle, Jonatan; Díaz Castro, Francisco; Donoso Barraza, Camila; Sepúlveda, Carlos; Pino de la Fuente, Francisco; Pino, Pamela; Espinosa Escalona, Berta; Chiong Lay, Mario; Llanos Silva, Miguel; Troncoso Cotal, Rodrigo (MDPI, 2020)
      Glucocorticoids (GCs) are critical regulators of energy balance. Their deregulation is associated with the development of obesity and metabolic syndrome. However, it is not understood if obesity alters the tissue glucocorticoid ...
    • Arias Téllez, María José; Acosta, Francisco M.; García Rivero, Yolanda; Pascual Gamarra, José; Merchan Ramírez, Elisa; Martínez Téllez, Borja; Silva, Analiza M.; López, Julio Almansa; Llamas Elvira, José; Ruiz, Jonatan (Springer, 2020)
      Objectives Neck adipose tissue (NAT) volume increases with general adiposity, with fat accumulating in different neck tissue compartments. In patients with certain malignant/benign tumours, the accumulation of NAT, and ...
    • Garrido Palma, Maritza; Torres, Ignacio; Ávila, Alba; Chnaiderman Figueroa, Jonas; Valenzuela Valderrama, Manuel; Aramburo, José; Oróstica, Lorena; Durán Jara, Eduardo; Lobos González, Lorena; Romero Osses, Carmen (MDPI, 2020)
      Nerve Growth Factor (NGF) and its high-affinity receptor tropomyosin receptor kinase A (TRKA) increase their expression during the progression of epithelial ovarian cancer (EOC), promoting cell proliferation and angiogenesis ...
    • Illesca, Paola; Valenzuela Báez, Rodrigo; Espinosa, Alejandra; Echeverría González, Francisca; Soto Alarcón, Sandra; Campos, Cristian; Rodríguez, Alicia; Vargas, Romina; Magrone, Thea; Videla Cabrera, Luis Alaberto (MDPI, 2020)
      Objective: Obesity induced by high-fat diet (HFD) elicits white adipose tissue dysfunction. In this study, we have hypothesized that the metabolic modulator eicosapentaenoic acid (EPA) combined with the antioxidant ...
    • Roa Cáceres, Cristian; Rosas Orrego, Camila (Sociedad Médica de Santiago, 2020)
      Paroxysmal sympathetic hyperactivity may appear after brain injury. Its clinical manifestations are sporadic and self-limited crisis of arterial hypertension, hyperthermia, tachycardia, hyperhidrosis, muscle tension, ...
    • González Hormazábal, Patricio; Retamales Ortega, Rocío; Musleh Katan, Maher; Bustamante, Marco; Stambuk, Juan; Pisano, Raúl; Valladares Hernández, Héctor; Lanzarini Sobrevía, Enrique; Chiong Tello, Héctor; Suazo, José; Quiñones Sepúlveda, Luis; Varela Figueroa, Nelson; Castro, Gonzalo; Jara, Lilian; Verdugo Salgado, Ricardo; Berger, Zoltan (Springer, 2020)
      Genetic variants are considered risk factors for gastric cancer. To date, 61 polymorphisms have been identified as associated with this disease. The aim of the present study was to analyze the association of some of those ...
    • Negrín, Roberto; Ferrer, Gonzalo; Iñiguez, Magaly; Duboy, Jaime; Saavedra, Manuel; Reyes Larraín, Nicolás; Jabes, Nicolás; Barahona Vásquez, Maximiliano (Springer, 2021)
      There is a high prevalence of knee osteoarthritis that affects only the medial tibiofemoral compartment. In this group of patients with severe disease, the medial unicompartmental knee arthroplasty (UKA) is an excellent ...
    • Vergara, Rodrigo C.; Jaramillo Riveri, Sebastián; Luarte, Alejandro; Moenne Loccoz, Cristóbal; Fuentes Flores, Rómulo; Couve Correa, Andrés Oscar; Maldonado Arbogast, Pedro (Frontiers Media, 2020)
    • Martínez Nahuel, Vania; Crockett, Marcelo; Jiménez Molina, Álvaro; Espinosa Duque, Daniel; Barrientos, Elisa; Ordóñez Carrasco, Jorge (Frontiers Media, 2020)
      Major depressive disorder (MDD) affects between 4 and 5% of adolescents. However, there is still a huge gap between adolescents who meet criteria for MDD and those who receive mental health care. Stigmatizing attitudes ...