Now showing items 581-600 of 11593

    • González, Andrea; Singh, Sandeep Kumar; Churruca Muñoz, Macarena; Maccioni Baraona, Ricardo Benjamín (MDPI, 2022)
      Alzheimer's disease (AD) is a multifactorial neurodegenerative disease characterized by progressive cognitive impairment, apathy, and neuropsychiatric disorders. Two main pathological hallmarks have been described: ...
    • Acuña Avila, Mirta; Benadof Fuentes, Dona; Yohannessen Vásquez, Karla; Leiva, Yennybeth; Clement Campillo, Pascale (BMC, 2022)
      Background: Central nervous system (CNS) infection has been an ongoing concern in paediatrics. The FilmArray (R) Meningoencephalitis (FAME) panel has greater sensitivity in identifying the aetiology of CNS infections. This ...
    • Adeyemo, Adebowale; Balaconis, Mary K.; Darnes, Deanna R.; Fatumo, Segun; Granados Moreno, Palmira; Hodonsky, Chani J.; Inouye, Michael; Kanai, Masahiro; Kato, Kazuto; Knoppers, Bartha M.; Lewis, Anna C. F.; Martin, Alicia R.; McCarthy, Mark I.; Meyer, Michelle N.; Okada, Yukinori; Richards, J. Brent; Richter, Lucas; Ripatti, Samuli; Rotimi, Charles N.; Sanderson, Saskia C.; Sturm, Amy C.; Verdugo Salgado, Ricardo Alejandro; Widen, Elisabeth; Willer, Cristen J.; Wojcik, Genevieve L.; Zhou, Alicia (Nature Research, 2021)
      Polygenic risk scores (PRSs) aggregate the many small effects of alleles across the human genome to estimate the risk of a disease or disease-related trait for an individual. The potential benefits of PRSs include ...
    • Bosch Amate, X.; Vargas Mora, Pablo Andrés; Morgado Carrasco, D. (Elsevier, 2021)
    • Rojas Erazo, Camilo Omar; Valenzuela Ahumada, Fernando Alfredo; Carreño Toro, Laura Elisa; González Coloma, Francisco (Mattioli 1885, Italy, 2021)
    • Neri, Piergiorgio; Herbort, Carl P.; Hedayatfar, Alireza; Tugal Tutkun, Ilknur; Cimino, Luca; Urzúa Salinas, Cristhian Alejandro; Papasavvas, Ioannis; Takeuchi, Masuru; Lages, Vania (Springer, 2022)
    • Hosiasson, Stefan; Beca, Juan Pablo; Vaisman Weinstein, Sergio (Elsevier, 2021)
      La historia de los inicios en Chile de la implementación nacional de las unidades de cuidados intensivos neonatales, y por ende de los inicios de la neonatología moderna en Chile, es de visionarios motivados exclusivamente ...
    • Pacheco, Rodrigo; Quezada, Sergio A.; Kalergis, Alexis M.; Becker, María Inés; Ferreira, Jorge; Ioannes, Alfredo E. de (Sociedad de Biología de Chile, 2021)
      Background: Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8+ efector T-cells and downregulated by CD4+ T-cells. However, the molecular mechanism by which urushiols stimulate innate ...
    • Ibáñez, Agustín; Pina Escudero, Stefanie Danielle; Possin, Katherine L.; Quiroz, Yakeel T.; Aguzzoli Peres, Fernando; Slachevsky Chonchol, Andrea María; Sosa, Ana Luisa; Brucki, Sonia M. D.; Miller, Bruce L (Elsevier, 2021)
      The prevalence of dementia in Latin America and the Caribbean is growing rapidly, increasing the burden placed on caregivers. Exacerbated by fragile health-care systems, unstable economies, and extensive inequalities, ...
    • García González, Paulina; Tempio Sepúlveda, Fabián Ignacio; Fuentes, Camila; Merino, Consuelo; Vargas, Leonardo; Simon, Valeska; Ramírez Pereira, Mirliana; Rojas, Verónica; Tobar Almonacid, Eduardo Andres; Landskron Ramos, Glauben Tamara; Araya, Juan Pablo; Navarrete, Mariela; Bastías Oñate, Carla Belén; Tordecilla Fernández, Rocío Pilar; Varas, Macarena A.; Maturana, Pablo; Marcoleta Caldera, Andrés Esteban; Allende Connelly, Miguel Luis; Naves Pichuante, Rodrigo Antonio; Hermoso, Marcela Alejandra; Salazar Onfray, Flavio Andrés; López Nitsche, Mercedes Natalia; Bono Merino, María Rosa; Osorio Olivares, Fabiola Beatriz (Frontiers Media, 2021)
      The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed to understand the immunological dynamics of ...
    • Cuzco, Cecilia; Torres Castro, Rodrigo Hernán; Torralba, Yolanda; Manzanares, Isabel; Muñoz Rey, Pilar; Romero García, Marta; Martínez Momblan, Ma. Antonia; Martínez Estalella, Gemma; Delgado Hito, Pilar; Castro, Pedro (MDPI, 2021)
      Intensive care unit discharge is an important transition that impacts a patient's wellbeing. Nurses can play an essential role in this scenario, potentiating patient empowerment. A systematic review was conducted using the ...
    • Marín Valdés, Arnaldo Andrés; Bull, Leonardo; Kinzie, Matthew; Andresen, Max (BMJ, 2021)
      The adequate handling of central venous catheters is a key element in the management of patients with cancer. Catheter-associated deep vein thrombosis is frequently observed in patients with malignant diseases; ...
    • Mazzucco Vezzera, Guillermo Andres; Pilon, Leonardo; Escalante, Juan Pablo; Chichizola, Nicolás; Torres Castro, Rodrigo Hernán (Cureus Inc, 2021)
      The treatment of choice for patients with advanced heart failure (HF) and with limiting symptoms with evidence of a poor prognosis despite optimal conventional treatment is a heart transplant. However, there is little ...
    • Zamorano, Mauricio; Castillo Peñaloza, Rodrigo Luis; Beltran, Jorge F.; Herrera, Lisandra; Farías, Joaquín A.; Antileo, Christian; Aguilar Gallardo, Cristóbal; Pessoa, Adalberto; Calle, Yolanda; Farías, Jorge G. (Frontiers Media, 2021)
      Ischemia is a severe condition in which blood supply, including oxygen (O), to organs and tissues is interrupted and reduced. This is usually due to a clog or blockage in the arteries that feed the affected organ. ...
    • Orellana, Omar; Amster Choder, Orna; Banerjee, Rajat; Ling, Jiqiang (Frontiers Media, 2021)
    • Irarrázaval Domínguez, Matías; Norambuena, Pablo; Montenegro, Cristian; Toro Devia, Olga; Vargas, Belén; Caqueo Urizar, Alejandra (Frontiers Media, 2021)
      Objectives: This paper reviews the mental health policies that have been implemented in Chile in response to the COVID-19 pandemic and the international context of countries' responses. Even before the start of the pandemic, ...
    • González Jara, Matías; Norambuena Norambuena, Scarlette; Inostroza Allende, Luis Felipe; Lennon Zaninovic, Loreto; Quezada Gaponov, Camilo Ernesto; Cornejo Farías, Javiera (Univ Castilla-La Mancha, 2021)
      Babies with cleft palate manifest problems in sucking dynamics, due to the communication between the nasal and oral cavity. The aim of the study was to characterize and compare general and feeding history in babies between ...
    • Altimir, Carolina; Jiménez, Juan Pablo (2021)
      After more than a century of existence, theoretical development, research, and clinical practice within the psychoanalytic movement have consistently demonstrated that psychoanalysis is not a unitary and autonomous ...
    • COVIDSurg Collaborative (Oxford Univ Press, England, 2021)
      To support the global restart of elective surgery, data from an international prospective cohort study of 8492 patients (69 countries) was analysed using artificial intelligence (machine learning techniques) to develop a ...
    • Fernández González, Loreto; Russo Namías, Moisés; Lagos, Rodrigo; Bravo, Paulina; Troncoso Vicencio, Alexis Ildefonso; Acevedo Echeverría, Claudia (Cancer Intelligence Ltd, England, 2021)
      Introduction: Developing instruments to screen for relevant aspects of advanced illness is key to identifying palliative needs and evaluating the effectiveness of interventions in this population. The objective of this ...