Now showing items 561-580 of 11593

    • Leao Ribeiro, Ivana; Gálvez González, Ximena; Lara Torres, Diego; Lorca, Luz Alejandra; Dixit, Snehil; Yáñez Benavides, Nicolás; Ortega González, Francisco (Hindawi, 2021)
      With treatment for breast cancer, women treated may present significant sensory abnormalities in the upper extremity. However, there are no conclusive studies that have evaluated pressure pain thresholds (PPT) in the ...
    • Berrios Cárcamo, Pablo; Quezada, Mauricio; Santapau, Daniela; Morales Retamales, Eugenia; Olivares, Belén; Ponce, Carolina; Ávila, Alba; Gregorio, Cristian de; Ezquer, Marcelo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy; Ezquer, Fernando (MDPI, 2022)
      An animal model of voluntary oral morphine consumption would allow for a pre-clinical evaluation of new treatments aimed at reducing opioid intake in humans. However, the main limitation of oral morphine consumption in ...
    • Córdova Delgado, Miguel Angel; Fuentes Retamal, Sebastián Andrés; Palominos, Charlotte; López Torres, Camila Alejandra; Guzmán Rivera, Daniela; Ramírez Rodríguez, Oney; Araya Maturana, Ramiro; Urra Faúndez, Félix Ariel (MDPI, 2021)
      Since breast cancer (BC) cells are dependent on mitochondrial bioenergetics for promoting proliferation, survival, and metastasis, mitochondria highlight as an important target for anticancer drug discovery. FRI-1, methyl ...
    • Valenzuela, Fernando; Fernández, Javier; Jiménez, Constanza; Cavagnola, Daniela; Mancilla, Juan Felipe; Astorga, Jessica; Hernández Ríos, Emma; Fernández, Alejandra (MDPI, 2021)
      : Psoriasis is a chronic immunoinflammatory skin disease. Although its diagnosis is clinical, differences in the appearance and severity of lesions pose a challenge for clinicians worldwide. The use of accessible biomarkers ...
    • Rojas, Claudio; Ewertz, Ernesto; Hormazábal, José Miguel (BMC, 2021)
      Background Failure of fixation (FF) in pubic symphysis diastasis (SD) ranges between 12 and 75%, though whether it influences functional outcomes is still debated. The objective of this study is to evaluate the impact of ...
    • Palma Behnke, Maria Alejandra; Rojas, Verónica; Ihl, Fernando; Ávila, Cristina; Plaza Parrochia, Francisca; Estuardo, Nivia; Castillo, Domingo (Elsevier, 2021)
      Background. The severity of the COVID-19 pandemic has resulted in limited provision of palliative care and hospital teams have had to rise to the challenge of how to deliver care safely to people with palliative needs. ...
    • Klahn A., Patricia; Barraza O., Marlon; González M., Claudio; Hernández M., Rubén; Sandoval C., Alejandra (Soc. Chilena Infectología, 2021)
      Los antimicrobianos corresponden al grupo de medicamentos más utilizados en Unidades de Cuidados Intensivos Neonatales; no obstante, su uso ha sido asociado a constantes errores de medicación en la práctica clínica. ...
    • Peñailillo, Johany; Palacios, Miriam; Mounieres, Constanza; Muñoz Videla, Rosana del Valle; Slater, Paula G.; Doménico, Elena de; Patrushev, Ilya; Gilchrist, Mike; Larraín, Juan (Nature, 2021)
      Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells (NSPCs). Here we use high-resolution expression profiling to characterize the early ...
    • Núñez Figueroa, Paulina; Quera, Rodrigo; Rubin, David T. (Baishideng Publishing, 2022)
      Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is a chronic immune-mediated inflammatory disease that primarily affects the gastrointestinal tract and is characterized by periods of ...
    • Kremer, Daan; Riemersma, Niels L.; Groothof, Dion; Sotomayor Campos, Camilo; Eisenga, Michele F.; Post, Adrian; Knobbe, Tim J.; Touw, Daan J.; Bakker, Stephan J. L. (MDPI, 2022)
      The nephrotoxic effects of heavy metals have gained increasing scientific attention in the past years. Recent studies suggest that heavy metals, including cadmium, lead, and arsenic, are detrimental to kidney transplant ...
    • Macias Mendoza, Marlon; Montes Robledo, Alfredo; Arteta Acosta, Cindy; Baldiris Avila, Rosa; Coronell Rodríguez, Wilfrido (Elsevier, 2022)
      The bacterium Neisseria meningitidis, a strictly human pathogen, can cause meningitis, meningococcemia, sepsis, and death; repeatedly it scause outbreaks around the world. The frequency of asymptomatic carriage is often ...
    • Núñez Figueroa, Paulina; Castro, Fabiola; Mezzano, Gabriel; Quera, Rodrigo; Díaz, Diego; Castro, Lorena (Baishideng Publishing, 2022)
      Inflammatory bowel diseases (IBD) are associated with various hepatobiliary disorders. They can occur at any moment in the course of the disease or associated with the treatment. The prevalence of liver dysfunction can ...
    • Oróstica Arévalo, Maria Lorena; Astorga Leiva, Isis; Plaza Parrochia, Francisca; Poblete Rivas, Cristian; Carvajal Gavilán, Rodrigo; García Angulo, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (MDPI, 2022)
      Polycystic ovary syndrome (PCOS) is an endocrine/metabolic disorder associated with insulin resistance (IR) and obesity. Endometria from women with PCOS present failures in insulin action, glucose uptake and signaling of ...
    • Maldonado Maldonado, Edio; Morales Pisón, Sebastian; Urbina, Fabiola; Solari Illescas, Aldo (MDPI, 2022)
      Chagas disease is caused by the protozoan Trypanosoma cruzi and is endemic to Central and South America. However, it has spread around the world and affects several million people. Treatment with currently available drugs ...
    • Pereira Montecinos, Camila; Toro Ascuy, Daniela; Ananías Sáez, Catarina; Gaete Argel, Aracelly; Rojas Fuentes, Cecilia; Riquelme Barrios, Sebastián; Rojas Araya, Bárbara; García de Gracia, Francisco; Aguilera Cortés, Paulina; Chnaiderman Figueroa, Jonas; Acevedo Acevedo, Mónica; Valiente Echeverría, Fernando; Soto Rifo, Ricardo (Oxford University Press, 2022)
      During retroviral replication, the full-length RNA serves both as mRNA and genomic RNA. However, the mechanisms by which the HIV-1 Gag protein selects the two RNA molecules that will be packaged into nascent virions remain ...
    • Lallas, A.; Martínez, G.; Arceu, M.; Kyrgidis, A.; Liopyris, K.; Brancaccio, G.; Longo, C.; Errichetti, E.; Sgouros, D.; Papageorgiou, C.; Fotiadou, C.; Siskou, S.; Manoli, S. M.; Sotiriou, E.; Ioannides, D.; Katoulis, A.; Lazaridou, E.; Todorovska, V.; Argenziano, G.; Apalla, Z. (Wiley, 2022)
      Background Squamous cell carcinoma of the lip accounts for 20% of all oral carcinomas. Its diagnosis may be challenging because it clinically resembles actinic cheilitis and inflammatory lesions of the lips. Objectives To ...
    • Pérez Castro, Pablo; Salas, Sofia P. (Wiley, 2021)
      Organ transplantation is a lifesaving procedure for end-organ damage and remains up to today as the most cost-effective alternative to treat these conditions. However, the main limitation to performing organ transplants ...
    • Leiva, Lorenzo Eugenio; Katz Zondek, Assaf (MDPI, 2022)
      In bacteria, the translation of genetic information can begin through at least three different mechanisms: canonical or Shine-Dalgarno-led initiation, readthrough or 70S scanning initiation, or leaderless initiation. Here, ...
    • García González, Paulina; Fernández, Dominique; Gutiérrez Cabrera, Diane; Parra Cordero, Mauro; Osorio Olivares, Fabiola (Wiley, 2022)
      The intracellular mechanisms safeguarding DC function are of biomedical interest in several immune-related diseases. Type 1 conventional DCs (cDC1s) are prominent targets of immunotherapy typified by constitutive activation ...
    • Anza Miranda, Fernanda; Aguilar Vidal, Enzo (Elsevier, 2022)
      Background: The activation of the medial olivocochlear reflex reduces the cochlear gain, which is manifested perceptually as decreased auditory sensitivity. However, it has remained unclear whether the extent of this ...