Now showing items 21-40 of 47

    • Gamonal Aravena, Jorge Antonio; Acevedo, A.; Bascones, A.; Jorge, O.; Silva, A. (American Academy of Periodontology, 2000)
      Background: Various cytokines have been identified at sites of chronic inflammation such as periodontitis. Cytokines are synthesized in response to bacteria and their products, inducing and maintaining an inflammatory ...
    • Dutzan Muñoz, Nicolás; Rivas, Catalina; García Sesnich, Jocelyn; Henríquez, Leslie; Rivera Escobar, Oriana; Dezerega Piwonka, Andrea; Hernández Ríos, Emma; Silva Steffens, Nora; Aguillón Gutiérrez, Juan Carlos; Puente Piccardo, Javier; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2011-10)
      BACKGROUND: A growing body of evidence suggested that interleukin (IL)-21 enhances the effector phase during T-cell responses. The aim of our study is to determine the levels of IL-21 in periodontal sites from patients ...
    • Pozo, P.; Valenzuela, M.; Melej, C.; Zaldívar, M.; Puente, J.; Martínez, B.; Gamonal Aravena, Jorge Antonio (2005)
      Background: The aim of this work was to improve the assessment of the periodontal disease status through measurements of extracellular matrix metalloproteinases (MMPs) and their tissular inhibitors (TIMPs) in the ...
    • Hernández Ríos, Emma; Valenzuela, María Antonieta; López Otin, Carlos; Alvarez, Jesús; López, José Manuel; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2006-11)
      Background: Matrix metalloproteinases (MMPs) participate in extracellular matrix degradation in physiological and pathological conditions. The available evidence suggests that MMP-13 plays a significant role in both the ...
    • Leppilahti, Jussi; Hernández Ríos, Patricia; Gamonal Aravena, Jorge Antonio; Tervahartiala, Taina; Brignardello Petersen, Romina; Mantyla, Paivi; Sorsa, Timo; Hernández, Marcela (2014)
      Aim: To identify the diagnostic accuracy of gingival crevicular fluid (GCF) candidate biomarkers to discriminate periodontitis from the inflamed and healthy sites, and to compare the performance of two independent matrix ...
    • Sorsa, Timo; Mäntylä, Päivi; Tervahartiala, Taina; Pussinen, Pirkko J.; Gamonal Aravena, Jorge Antonio; Hernández Ríos, Emma (John Wiley & Sons A/S, 2011-09)
    • Hernández Ríos, Emma; Martínez, Benjamín; Tejerina, José María; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (2007)
      Matrix metalloproteinase (MMP)-13 is a collagenase involved in extracellular matrix degradation either by its direct degradative effects or by processing bioactive substrates. The aim of this study was to determine the ...
    • Dezerega Piwonka, Andrea; Osorio Alfaro, Constanza; Mardones Peñailillo, Jeannette Isabel; Mundi, V.; Dutzan Muñoz, Nicolás; Franco Martínez, María Eugenia; Gamonal Aravena, Jorge Antonio; Oyarzún Droguett, Alejandro; Overall, M. C.; Hernández Ríos, Emma (John Wiley & Sons, 2010-10)
      Aim  To study the expression of monocyte chemotactic protein-3 (MCP-3, also known as chemokine CCL-7) in tissue from apical lesions (AL) and to associate MCP-3 expression with symptomatic or asymptomatic apical ...
    • Bascones, Antonio; Gamonal Aravena, Jorge Antonio; Gómez Carranza, María Leyla; Silva, Augusto; González, Miguel Ángel (Quintessence Publishing, 2004-10)
      The aim of this study was to evaluate the relationship between the accumulation of interleukins IL-1beta, TNF-alpha, IL-8, and chemokine RANTES (Regulated upon Activation Normal T-cell Expressed and Secreted) in gingival ...
    • Dutzan Muñoz, Nicolás; Gamonal Aravena, Jorge Antonio; Silva, Augusto; Sanz, Mariano; Vernal Astudillo, Rolando (John Wiley, 2009)
      Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-k B ligand (RANKL). The aim of ...
    • Dutzan Muñoz, Nicolás; Gamonal Aravena, Jorge Antonio; Silva, Augusto; Sanz, Mariano; Vernal Astudillo, Rolando (John Wiley & Sons, 2009-05)
      Aim: T regulatory (Treg) cells have been detected in periodontitis lesions, and forkhead box P3 (Foxp3) expression has been negatively correlated to receptor activator of nuclear factor-κ B ligand (RANKL). The aim of this ...
    • Gamonal Aravena, Jorge Antonio; López Villarroel, Néstor; Aranda Chacón, Waldo (FDI/World Dental Press, 1998-04)
      A CPITN survey involving Chileans aged 35-44 and 65-74 was conducted. A random, stratified sample by age, gender, socio-economic status and educational level was obtained, comprising 1150 individuals. Prevalence of chronic ...
    • Carré, L.; Franco Martínez, María Eugenia; Henríquez, L.; García Sesnich, Jocelyn; Dutzan Muñoz, Nicolás; Aguillón Gutiérrez, Juan Carlos; Gamonal Aravena, Jorge Antonio (Sociedad de Periodoncia de Chile., 2010-12)
      La enfermedad periodontal requiere de un hospedero susceptible para su desarrollo y progresión. Dentro de las características del hospedero se encuentra la respuesta T reguladora, que otorga tolerancia frente a antígenos ...
    • Morales, Alicia; Carvajal Pavez, Paola; Romanelli, Hugo; Gómez, Mariel; Loha, Cristina; Esper, María E.; Musso, Graciela; Ardila, Carlos M.; Duque, Andrés; Medina, Marco; Bueno, Luis; Andrade, Ernesto; Mendoza, Carolina; Gamonal Aravena, Jorge Antonio (Wiley & Sons, 2015)
      Aim: To describe the prevalence, severity and extension of clinical attachment loss (CAL) and to study the predictors in 15- to 19-year-old adolescents from high schools in the Latin America. Materials and Methods: A ...
    • Espinoza Santander, Iris; Rojas, R.; Aranda, W.; Gamonal Aravena, Jorge Antonio (2003)
      BACKGROUND: Oral prevalence studies are important to know the state of health and the needs of treatment. Our aim was to determine the prevalence of oral mucosal lesions and associated factors among aging Chileans. METHODS: A ...
    • Espinoza Santander, Iris; Rojas, R.; Aranda Chacón, Waldo; Gamonal Aravena, Jorge Antonio (Blacwell Munksgaard, 2003-11)
      Background:  Oral prevalence studies are important to know the state of health and the needs of treatment. Our aim was to determine the prevalence of oral mucosal lesions and associated factors among aging Chileans. Methods:  ...
    • Gajardo, Marta; Silva Steffens, Nora; Gómez, Leyla; León Berríos, Rubén; Parra, Beatriz; Contreras, Adolfo; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2005-02)
      Background: Actinobacillus actinomycetemcomitans is considered a major etiologic agent of aggressive periodontitis (AgP). Other periodontopathic bacteria such as Porphyromonas gingivalis are also suspected of participating ...
    • Hernández Ríos, Emma; Sorsa, Timo; Obregón, Fabián; Tervahartiala, Taina; Valenzuela, María Antonieta; Pozo, Patricia; Dutzan Muñoz, Nicolás; Lesaffre, Emmanuel; Molas, Marek; Gamonal Aravena, Jorge Antonio (European Federation of Periodontology, 2009-12)
      Aim: Matrix metalloproteinases (MMP)-13 can initiate bone resorption and activate proMMP-9 in vitro, and both these MMPs have been widely implicated in tissue destruction associated with chronic periodontitis. We studied ...
    • Vernal Astudillo, Rolando; Dezerega Piwonka, Andrea; Dutzan Muñoz, Nicolás; Chaparro, Alejandra; León Berríos, Rubén; Chandía Espinosa, Sabrita; Silva, A.; Gamonal Aravena, Jorge Antonio (BLACKWELL, 2006-05)
      OBJECTIVES: The cytokine receptor activator of nuclear factor kappa B-ligand (RANKL) has been involved in both the physiological and pathological regulation of osteoclast life span and bone metabolism. Periapical granuloma ...
    • Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Salo, T.; Tervahartiala, Taina; Hukkanen, M.; Tjäderhane, L.; Sorsa, Timo (John Wiley & Sons A/S, 2011-02)
      Background and Objective:  Matrix metalloproteinase-8 (MMP-8) is a central mediator in chronic periodontitis. Recently developed MMP-8-deficient mice show an impaired polymorphonuclear neutrophil response and more severe ...