Browsing by Author "Guyatt, Gordon H."

Now showing items 1-20 of 20

    • Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review ... 
      Agarwal, Arnav; Johnston, Bradley; Vernooij, Robin; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramirez-Morera, Anggie; Selva, Anna; Solà, Ivan; Sanabrai, Andrea; Tikkinen, Kari; Vandvik, Per; Zhang, Yuqing; Zazueta, Oscar; Zhou, Qi; Schunemann, Holger J.; Guyatt, Gordon H.; Alonso Coello, Pablo (Elsevier USA, 2017)
      Objectives Explicit reporting of absolute measures is important to ensure treatment effects are correctly interpreted. We examined the extent to which authors report absolute effects for patient-important outcomes in ...
    • Comparison between the standard and a new alternative format of the Summary-of-Findings tables in Cochrane ... 
      Carrasco Labra, Alonso; Brignardello Petersen, Romina; Santesso, Nancy; Neumann, Ignacio; Mustafa, Reem; Mbuagbaw, Lawrence; Etxeandia Ikobaltzeta, Itziar; De Stio, Catherine; McCullagh, Lauren; Alonso Coello, Pablo; Meerpohl, Joerg; Vandvik, Per Olav; Brozek, Jan; Akl, Elie; Bossuyt, Patrick; Churchill, Rachel; Glenton, Claire; Rosenbaum, Sarah; Tugwell, Peter; Welch, Vivian; Guyatt, Gordon H.; Schuenemann, Holger (BIOMED CENTRAL, 2015)
      Background: Systematic reviews represent one of the most important tools for knowledge translation but users often struggle with understanding and interpreting their results. GRADE Summary-of-Findings tables have been ...
    • Completion and Publication Rates of Randomized Controlled Trials in Surgery An Empirical Study 
      Rosenthal, Rachel; Kasenda, Benjamin; Dell-Kuster, Salome; Elm, Erik von; You, John; Bluemle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Sohail, Mulla; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Olu, Kelechi K.; Raatz, Heike; Moja, Lorenzo; Ebrahim, Shanil; Schandelmaier, Stefan; Sun, Xin; Vandvik, Per O.; Bradley C., Johnston; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (Lippicott Williams & Wilkins, 2015)
      Objective: To investigate the prevalence of discontinuation and nonpublication of surgical versus medical randomized controlled trials (RCTs) and to explore risk factors for discontinuation and nonpublication of surgical ...
    • Do clinicians want recommendations? A multicenter study comparing evidence summaries with and without GRADE ... 
      Neumann, Ignacio; Alonso Coello, Pablo; Olav Vandvik, Per; Agoritsas, Thomas; Mas, Gemma; Akl, Elie; Brignardello Petersen, Romina; Emparanza, José; McCullagh, Lauren; De Sitio, Catherine; McGinn, Thomas; Almodaimegh, Hind; Almodaimegh, Khalid; Rivera, Solange; Roja, Luis; Stirnemann, Jérôme; Irani, Jihad; Hlais, Sani; Mustafa, Reem; Bdair, Fadi; Aly, Abdelrahman; Kristiansen, Annette; Izcovich, Ariel; Ramirez, Anggie; Brozek, Jan; Guyatt, Gordon H.; Sch€unemann, Holger (Elsevier USA, 2018)
      Objectives: Evidence-based clinical practice guidelines provide recommendations to assist clinicians in decision-making and to reduce the gap between best current research evidence and clinical practice. However, some ...
    • Economic analysis studies response 
      Abrahamyan, Lusine; Pechlivanoglou, Petros; Krahn, Murray; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2016)
    • The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses 
      Mustafa, Reem A.; Santesso, Nancy; Brozek, Jan; Akl, Elie A.; Walter, Stephen D.; Norman, Geoff; Kulasegaram, Mahan; Christensen, Robin; Guyatt, Gordon H.; Falck Ytter, Yngve; Chang, Stephanie; Hassan Murad, Mohammad; Vist, Gunn E.; Lasserson, Toby; Gartlehner, Gerald; Shukla, Vijay; Sun, Xin; Whittington, Craig; Post, Piet N.; Lang, Eddy; Thaler, Kylie; Kunnamo, Ilkka; Alenius, Heidi; Meerpohl, Joerg J.; Alba, Ana C.; Nevis, Immaculate F.; Gentles, Stephen; Ethier, Marie Chantal; Carrasco Labra, Raúl; Khatib, Rasha; Nesrallah, Gihad; Kroft, Jamie; Selk, Amanda; Brignardello Petersen, Romina; Schünemann, Holger J. (Elsevier, 2013)
      Objective: We evaluated the inter-rater reliability (IRR) of assessing the quality of evidence (QoE) using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Study Design and Setting: ...
    • Hypnosis/Relaxation Therapy for Temporomandibular Disorders: A Systematic Review and Meta-Analysis of ... 
      Zhang, Yuqing; Montoya, Luis; Ebrahim, Shanil; Busse, Jason W.; Couban, Rachel; McCabe, Randi E.; Bieling, Peter; Carrasco Labra, Alonso; Guyatt, Gordon H. (QUINTESSENCE PUBLISHING, 2015)
      Aims: To conduct a systematic review and meta-analysis to evaluate the effectiveness of hypnosis/relaxation therapy compared to no/minimal treatment in patients with temporomandibular disorders (TMD). Methods: Studies ...
    • Living cumulative network meta-analysis to reduce waste in research: A paradigmatic shift for systematic reviews? 
      Vandvik, Per; Brignardello Petersen, Romina; Guyatt, Gordon H. (BIOMED CENTRAL, 2016)
      In a recent research article in BMC Medicine, Crequit and colleagues demonstrate how published systematic reviews in lung cancer provide a fragmented, out-of-date picture of the evidence for all treatments. The results and ...
    • Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol 
      Wu, Darong; Akl, Elie A.; Guyatt, Gordon H.; Devereaux, Philip J.; Brignardello Petersen, Romina; Prediger, Barbara; Patel, Krupesh; Patel, Namrata; Lu, Taoying; Zhang, Yuan; Falavigna, Maicon; Santesso, Nancy; Mustafa, Reem A.; Zhou, Qi; Briel, Matthias; Schünemann, Holger J. (BioMed Central Ltd., 2014)
      Background: Although even randomization (that is, approximately 1:1 randomization ratio in study arms) provides the greatest statistical power, designed uneven randomization (DUR), (for example, 1:2 or 1:3) is used to ...
    • Minimally important difference estimates and methods: a protocol 
      Johnston, Bradley C.; Ebrahim, Shanil; Carrasco Labra, Alonso; Furukawa, Toshi A.; Patrick, Donald L.; Crawford, Mark W.; Hemmelgarn, Brenda R.; Schunemann, Holger J.; Guyatt, Gordon H.; Nesrallah, Gihad (BMJ Publishing Group, 2015)
      Introduction Patient-reported outcomes (PROs) are often the outcomes of greatest importance to patients. The minimally important difference (MID) provides a measure of the smallest change in the PRO that patients perceive ...
    • A practical approach to evidence-based dentistry: III How to appraise and use an article about therapy 
      Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (AMER DENTAL ASSOC, 2015)
      Background and Overview. Dental practitioners spend most of their time administering treatments. To ensure that their clinical decisions are informed by the best available evidence, dental practitioners need to be skilled ...
    • A practical approach to evidence-based dentistry: IV How to use an article about harm 
      Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Questions regarding harm are common in dental practice. Observational, nonrandomized studies (that is, cohort studies and casecontrol studies) are the designs used by investigators to answer most ...
    • A practical approach to evidence-based dentistry: IX How to appraise and use an article about economic analysis 
      Abrahamyan, Lusine; Pechlivanoglou, Petros; Krahn, Murray; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (American Dental Association, 2015)
      Background and Overview. In everyday practice, dentists face clinical decisions for which they need to consider both treatment consequences (that is, benefits and harms) and costs. Economic analysis is a study design in ...
    • A practical approach to evidence-based dentistry: V How to appraise and use an article about diagnosis 
      Brignardello Petersen, Romina; Carrasco Labra, Alonso; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Questions regarding diagnosis are common in dental practice. Studies in which investigators apply a diagnostic test and a reference standard to all patients and compare their results represent the ...
    • A practical approach to evidence-based dentistry: VIII How to appraise an article based on a qualitative study 
      Sale, Joanna E. M; Amin, Maryam; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Glick, Michael; Guyatt, Gordon H.; Azarpazhooh, Amir (Amer Dental Assoc, 2015)
      Background and Overview. Because of qualitative researchers' abilities to explore social problems and to understand the perspective of patients, qualitative research studies are useful to provide insight about patients' ...
    • Prevalence, Characteristics, and Publication of Discontinued Randomized Trials 
      Kasenda, Benjamin; Von Elm, Erik; You, John; Blümle, Anette; Tomonaga, Yuki; Saccilotto, Ramón; Amstutz, Alain; Bengough, Theresa; Meerpohl, Joerg J.; Stegert, Mihaela; Tikkinen, Kari A. O.; Neumann, Ignacio; Carrasco Labra, Alonso; Faulhaber, Markus; Mulla, Sohail M.; Mertz, Dominik; Akl, Elie A.; Bassler, Dirk; Busse, Jason W.; Ferreira González, Ignacio; Lamontagne, Francois; Nordmann, Alain; Gloy, Viktoria; Raatz, Heike; Moja, Lorenzo; Rosenthal, Rachel; Ebrahim, Shanil; Schandelmaier, Stefan; Xin, Sun; Vandvik, Per O.; Johnston, Bradley C.; Walter, Martin A.; Burnand, Bernard; Schwenkglenks, Matthias; Hemkens, Lars G.; Bucher, Heiner C.; Guyatt, Gordon H.; Briel, Matthias (American Medical Association., 2014)
      IMPORTANCE The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of discontinued RCTs, however, remains unclear. OBJECTIVES To ...
    • Reporting missing participant data in randomised trials: systematic survey of the methodological literature ... 
      Akl, Elie A; Shawwa, Khaled; Kahale, Lara A.; Agoritsas, Thomas; Brignardello Petersen, Romina; Busse, Jason W.; Carrasco Labra, Alonso; Ebrahim, Shanil; Johnston, Bradley C.; Neumann, Ignacio; Solà, Iván; Sun, Xin; Vandvik, Per; Zhang, Yuqing; Alonso Coello, Pablo; Guyatt, Gordon H. (BMJ Publishing Group, 2015)
      Objectives We conducted a systematic survey of the methodological literature to identify recommended approaches for how and what randomised clinical trial (RCT) authors should report on missing participant data and, on the ...
    • Reporting, handling and assessing the risk of bias associated with missing participant data in systematic ... 
      Akl, Elie A.; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Johnston, Bradley C.; Sun, Xin; Briel, Matthias; Busse, Jason W.; Ebrahim, Shanil; Granados, Carlos E.; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem A.; Ramírez Morera, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea Juliana; Tikkinen, Kari A. O.; Vandvik, Per O.; Vernooij, Robin W. M.; Zazueta, Oscar E.; Zhou, Qi; Guyatt, Gordon H.; Alonso Coello, Pablo (BMJ, 2015)
      Objectives: To describe how systematic reviewers are reporting missing data for dichotomous outcomes, handling them in the analysis and assessing the risk of associated bias. Methods: We searched MEDLINE and the Cochrane ...
    • Systematic reviews experience major limitations in reporting absolute effects 
      Alonso Coello, Pablo; Carrasco Labra, Alonso; Brignardello Petersen, Romina; Neumann, Ignacio; Akl, Elie; Vernooij, Robin; Johnston, Brad; Sun, Xin; Briel, Matthias; Busse, Jason; Ebrahim, Shanil; Granados, Carlos; Iorio, Alfonso; Irfan, Affan; Martínez García, Laura; Mustafa, Reem; Ramírez Morers, Anggie; Selva, Anna; Solà, Iván; Sanabria, Andrea; Tikkinen, Kari; Vandvik, Per; Zazueta, Oscar; Zhang, Yuqing; Zhou, Qi; Schünemann, Holger; Guyatt, Gordon H. (Elsevier, 2016)
      Objectives: Expressing treatment effects in relative terms yields larger numbers than expressions in absolute terms, affecting the judgment of the clinicians and patients regarding the treatment options. It is uncertain ...
    • The effectiveness of splint therapy in patients with temporomandibular disorders: A systematic review and ... 
      Ebrahim, Shanil; Montoya, Luis; Busse, Jason; Carrasco Labra, Alonso; Guyatt, Gordon H. (American Dental Association, 2012)
      Purpose The authors conducted a systematic review of all published randomized controlled trials in which investigators compared the effectiveness of splint therapy with that of minimal or no treatment in patients with ...