Now showing items 1-20 of 20

    • Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Tervahartiala, Taina; Mäntylä, Päivi; Rivera Escobar, Oriana; Dezerega Piwonka, Andrea; Dutzan, N.; Sorsa, T. (American Academy of Periodontology, 2010-11)
      Background: Matrix metalloproteinase (MMP)-8 is a central mediator in chronic periodontitis. MMP-8 can be activated by the cooperative action of otherMMPs such asMMP-14, reactive oxygen species, andmicrobial proteases. ...
    • Dezerega Piwonka, Andrea; Pozo, Patricia; Hernández Ríos, Emma; Oyarzún Droguett, Alejandro; Rivera Escobar, Oriana; Dutzan Muñoz, Nicolás; Gutiérrez Fernández, Ana; Overall, Christopher M.; Garrido, Mauricio; Alcota Rojas, Marcela; Ortiz, Emilio; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2010-02)
      Background: Chemokines are central in the activation and direction of leukocyte subsets to target tissues. However, the monocyte chemoattractant protein-3 (MCP-3) has not been associated with chronic periodontitis. Chronic ...
    • Sorsa, Timo; Tervahartiala, Taina; Leppilahti, Jussi; Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Tuomainen, Anita M.; Lauhio, Anneli; Pussinen, Pirkko J.; Mäntylä, Päivi (Elsevier, 2011-02)
      Neutrophil collagenase or collagenase-2 (matrix metalloproteinase [MMP]-8) belongs to the collagenase subgroup of the MMP superfamily of calcium- and zinc-dependent neutral proteinases. MMP-8 is catalytically the most ...
    • Bordagaray San Martín, María José; Fernández, Alejandra; Astorga, Jessica; Garrido Flores, Carlos Mauricio; Hernández Ríos, Patricia; Chaparro, Alejandra; Lira, María Jesús; Gebicke Haerter, Peter; Hernández Ríos, Emma (Frontiers Media, 2022)
      IntroductionApical periodontitis (AP) is a common oral disease caused by the inflammatory destruction of the periapical tissues due to the infection of the root canal system of the tooth. It also contributes to systemic ...
    • Sorsa, Timo; Hernández Ríos, Emma; Leppilahti, Jussi; Munjal, S.; Netuschil, L.; Mäntylä, Päivi (John Wiley & Sons, 2010)
      OBJECTIVE: The aim of the study was to compare four methods for gingival crevicular fluid (GCF) matrix metalloproteinase (MMP)-8 detection. METHODS: Matrix metalloproteinase-8 levels from 20 GCF samples from two ...
    • Belmar, María José; Pabst, Carolina; Martínez, Benjamín; Hernández Ríos, Emma (MOSBY-ELSEVIER, 2008-06)
      Objective. Many matrix metalloproteinases ( MMPs) have been associated with periodontal tissue destruction during chronic and apical periodontitis. The aim of this study was to determine gelatinolytic activity in gingival ...
    • Hernández Ríos, Emma; Dutzan Muñoz, Nicolás; García Sesnich, Jocelyn; Abusleme Ramos, Loreto Andrea; Dezerega Piwonka, Andrea; Silva Steffens, Nora; González Bergas, Fermín; Vernal Astudillo, Rolando; Sorsa, T.; Gamonal Aravena, Jorge Antonio (Sage, 2011-10)
      Periodontitis is an infection characterized by the occurrence of supporting tissue destruction with an episodic nature. Disease progression is often determined by the loss of attachment level or alveolar bone, and sequential ...
    • Dutzan Muñoz, Nicolás; Vernal Astudillo, Rolando; Hernández Ríos, Emma; Dezerega Piwonka, Andrea; Rivera Escobar, Oriana; Silva Steffens, Nora; Aguillón Gutiérrez, Juan Carlos; Puente Piccardo, Javier; Pozo, Patricia; Gamonal Aravena, Jorge Antonio (2009-02)
      Background: Periodontitis is an infection with an episodic pattern of tissue-support destruction. During the generation of a primary CD4+ T helper 1 (Th1) response, interferon-gamma (IFN-g) acts as a positive regulator ...
    • Dutzan Muñoz, Nicolás; Rivas, Catalina; García Sesnich, Jocelyn; Henríquez, Leslie; Rivera Escobar, Oriana; Dezerega Piwonka, Andrea; Hernández Ríos, Emma; Silva Steffens, Nora; Aguillón Gutiérrez, Juan Carlos; Puente Piccardo, Javier; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2011-10)
      BACKGROUND: A growing body of evidence suggested that interleukin (IL)-21 enhances the effector phase during T-cell responses. The aim of our study is to determine the levels of IL-21 in periodontal sites from patients ...
    • Hernández Ríos, Emma; Valenzuela, María Antonieta; López Otin, Carlos; Alvarez, Jesús; López, José Manuel; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2006-11)
      Background: Matrix metalloproteinases (MMPs) participate in extracellular matrix degradation in physiological and pathological conditions. The available evidence suggests that MMP-13 plays a significant role in both the ...
    • Cavalla Ruiz, Ian; Osorio Alfaro, Constanza; Paredes, Rodolfo; Valenzuela Pedevila, María Antonieta; García Sesnich, Jocelyn; Sorsa, Timo; Tervahartiala, Taina; Hernández Ríos, Emma (Elsevier, 2015)
      Periodontitis is a highly prevalent infectious disease characterized by the progressive inflammatory destruction of tooth-supporting structures, leading to tooth loss. The underling molecular mechanisms of the disease ...
    • Sorsa, Timo; Mäntylä, Päivi; Tervahartiala, Taina; Pussinen, Pirkko J.; Gamonal Aravena, Jorge Antonio; Hernández Ríos, Emma (John Wiley & Sons A/S, 2011-09)
    • Hernández Ríos, Emma; Martínez, Benjamín; Tejerina, José María; Valenzuela, María Antonieta; Gamonal Aravena, Jorge Antonio (2007)
      Matrix metalloproteinase (MMP)-13 is a collagenase involved in extracellular matrix degradation either by its direct degradative effects or by processing bioactive substrates. The aim of this study was to determine the ...
    • Dezerega Piwonka, Andrea; Osorio Alfaro, Constanza; Mardones Peñailillo, Jeannette Isabel; Mundi, V.; Dutzan Muñoz, Nicolás; Franco Martínez, María Eugenia; Gamonal Aravena, Jorge Antonio; Oyarzún Droguett, Alejandro; Overall, M. C.; Hernández Ríos, Emma (John Wiley & Sons, 2010-10)
      Aim  To study the expression of monocyte chemotactic protein-3 (MCP-3, also known as chemokine CCL-7) in tissue from apical lesions (AL) and to associate MCP-3 expression with symptomatic or asymptomatic apical ...
    • Leppilahti, Jussi; Ahonen, M.-M.; Hernández Ríos, Emma; Munjal, S.; Netuschil, L.; Uitto, V.-J.; Sorsa, Timo; Mäntylä, Päivi (John Wiley, 2011)
      OBJECTIVE: To determine whether oral rinse matrix metalloproteinase (MMP)-8 levels, measured by three different methods, tissue inhibitor of matrix metalloprotease- 1 (TIMP-1) levels and elastase activity differentiat ...
    • Espinoza Santander, Iris; Orellana B., Alejandra; Hernández Ríos, Emma; Rojas Solar, René (Universidad de Chile. Facultad de Odontología, 1999)
      Individuals older tan sixty years (elderly population) prsent the major prevalence of oral mucosal lesions, according to several clinic epidemiological sulveys. However, because of they lack of histologycal confirmation ...
    • Bendek, María José; Canedo Marroquín, Gisela; Realini, Ornella; Retamal, Ignacio N.; Hernández Ríos, Emma; Hoare Teuche, Anilei Paz; Busso, Dolores; Monteiro, Lara J.; Illanes, Sebastián E.; Chaparro, Alejandra (MDPI, 2021)
      Periodontitis is a chronic inflammatory immune disease associated with a dysbiotic state, influenced by keystone bacterial species responsible for disrupting the periodontal tissue homeostasis. Furthermore, the severity ...
    • Hernández Ríos, Emma; Sorsa, Timo; Obregón, Fabián; Tervahartiala, Taina; Valenzuela, María Antonieta; Pozo, Patricia; Dutzan Muñoz, Nicolás; Lesaffre, Emmanuel; Molas, Marek; Gamonal Aravena, Jorge Antonio (European Federation of Periodontology, 2009-12)
      Aim: Matrix metalloproteinases (MMP)-13 can initiate bone resorption and activate proMMP-9 in vitro, and both these MMPs have been widely implicated in tissue destruction associated with chronic periodontitis. We studied ...
    • Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Salo, T.; Tervahartiala, Taina; Hukkanen, M.; Tjäderhane, L.; Sorsa, Timo (John Wiley & Sons A/S, 2011-02)
      Background and Objective:  Matrix metalloproteinase-8 (MMP-8) is a central mediator in chronic periodontitis. Recently developed MMP-8-deficient mice show an impaired polymorphonuclear neutrophil response and more severe ...
    • Díaz Zúñiga, Jaime; Yáñez Figueroa, Juan Pablo; Álvarez, Carla; Melgar Rodríguez, Samanta; Hernández Ríos, Emma; Sanz, Mariano; Vernal Astudillo, Rolando (2014)
      Aim: Different serotypes of Aggregatibacter actinomycetemcomitans have been described based on the lipopolysaccharide (LPS)-O-polysaccharide antigenicity. In turn, a distinct effect of A. actinomycetemcomitans serotypes ...