Now showing items 1-8 of 8

    • Hernández Ríos, Marcela; Baeza Paredes, Mauricio Enrique; Raisanen, Ismo; Contreras Balbontín, Johanna; Tervahartiala, Taina; Chaparro, Alejandra; Sorsa, Timo; Hernández Ríos, Patricia (MDPI, 2021)
      Periodontitis is a host-mediated bacterial disease that affects the tooth attachment apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical diagnosis. This study aimed to evaluate the diagnostic ...
    • Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Tervahartiala, Taina; Mäntylä, Päivi; Rivera Escobar, Oriana; Dezerega Piwonka, Andrea; Dutzan, N.; Sorsa, T. (American Academy of Periodontology, 2010-11)
      Background: Matrix metalloproteinase (MMP)-8 is a central mediator in chronic periodontitis. MMP-8 can be activated by the cooperative action of otherMMPs such asMMP-14, reactive oxygen species, andmicrobial proteases. ...
    • Sorsa, Timo; Tervahartiala, Taina; Leppilahti, Jussi; Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Tuomainen, Anita M.; Lauhio, Anneli; Pussinen, Pirkko J.; Mäntylä, Päivi (Elsevier, 2011-02)
      Neutrophil collagenase or collagenase-2 (matrix metalloproteinase [MMP]-8) belongs to the collagenase subgroup of the MMP superfamily of calcium- and zinc-dependent neutral proteinases. MMP-8 is catalytically the most ...
    • Baeza Paredes, Mauricio; Garrido Flores, Carlos; Hernández Ríos, Patricia; Dezerega Piwonka, Andrea; García Sesnich, Jocelyn; Strauss Avendaño, Franz; Aitken Saavedra, Juan; Lesaffre, Emmanuel; Vanbelle, Sophie; Gamonal Aravena, Jorge Antonio; Brignardello Petersen, Romina; Tervahartiala, Taina; Sorsa, Timo; Hernández Ríos, Marcela (Wiley, 2016)
      AimThe aim of this study was to assess the levels and diagnostic accuracy of a set of potential biomarkers of periodontal tissue metabolism in gingival crevicular fluid (GCF) from patients with chronic periodontitis (CP) ...
    • Cavalla Ruiz, Ian; Osorio Alfaro, Constanza; Paredes, Rodolfo; Valenzuela Pedevila, María Antonieta; García Sesnich, Jocelyn; Sorsa, Timo; Tervahartiala, Taina; Hernández Ríos, Emma (Elsevier, 2015)
      Periodontitis is a highly prevalent infectious disease characterized by the progressive inflammatory destruction of tooth-supporting structures, leading to tooth loss. The underling molecular mechanisms of the disease ...
    • Sorsa, Timo; Mäntylä, Päivi; Tervahartiala, Taina; Pussinen, Pirkko J.; Gamonal Aravena, Jorge Antonio; Hernández Ríos, Emma (John Wiley & Sons A/S, 2011-09)
    • Hernández Ríos, Emma; Sorsa, Timo; Obregón, Fabián; Tervahartiala, Taina; Valenzuela, María Antonieta; Pozo, Patricia; Dutzan Muñoz, Nicolás; Lesaffre, Emmanuel; Molas, Marek; Gamonal Aravena, Jorge Antonio (European Federation of Periodontology, 2009-12)
      Aim: Matrix metalloproteinases (MMP)-13 can initiate bone resorption and activate proMMP-9 in vitro, and both these MMPs have been widely implicated in tissue destruction associated with chronic periodontitis. We studied ...
    • Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Salo, T.; Tervahartiala, Taina; Hukkanen, M.; Tjäderhane, L.; Sorsa, Timo (John Wiley & Sons A/S, 2011-02)
      Background and Objective:  Matrix metalloproteinase-8 (MMP-8) is a central mediator in chronic periodontitis. Recently developed MMP-8-deficient mice show an impaired polymorphonuclear neutrophil response and more severe ...