Browsing by Author "Aliaga, Margarita E."
Now showing items 1-4 of 4
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Aliaga, Margarita E.; Carrasco Pozo, Catalina; López Alarcón, Camilo; Speisky Cosoy, Hernán (Springer, 2010)Cu2? ions and reduced glutathione (GSH) swiftly interact to form the physiologically occurring Cu(I)–[GSH]2 complex. Prompted by the recently reported ability of this complex to generate superoxide radicals from molecular ...
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Cu(II)–disulfide complexes display simultaneous superoxide dismutase- and catalase-like activities Aliaga, Margarita E.; Andrade Acuña, Daniela; López Alarcón, Camilo; Sandoval Acuña, Cristián; Speisky Cosoy, Hernán (Elsevier, 2013)Superoxide is a potentially toxic by-product of cellular metabolism.We have addressed here the in vitro ability of complexes formed between copper(II) ions and various biologically-occurring disulfides (RSSR: oxidized ...
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Carrasco Pozo, Catalina; Aliaga, Margarita E.; Olea Azar, Claudio; Speisky Cosoy, Hernán (PERGAMON-ELSEVIER, 2008-11-15)The present study investigated the redox-consequences of the interaction between various endogenous thiols (RSH)-glutathione, cysteine, homocysteine, c-glutamyl-cysteine, and cysteinyl-glycine-and Cu2+ ions, in terms of ...
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Aliaga, Margarita E.; López Alarcón, Camilo; Bridi, Raquel; Speisky Cosoy, Hernán (Elsevier, 2016)Binding of copper by reduced glutathione (GSH) is generally seen as a mechanism to lower, if not abolish, the otherwise high electrophilicity and redox activity of its free ions. In recent years, however, this concept has ...