Browsing by Subject "Gene"

Now showing items 1-3 of 3

    • FMR1 mRNA from full mutation alleles is associated with ABC-C-FX scores in males with fragile X syndrome 
      Baker, Emma K.; Arpone, Marta; Kraan, Claudine; Bui, Minh; Rogers, Carolyn; Field, Michael; Bretherton, Lesley; Ling, Ling; Ure, Alexandra; Cohen, Jonathan; Hunter, Matthew F.; Santa María Vásquez, Lorena; Faúndes Gómez, Víctor; Curotto, Bianca; Morales, Paulina; Trigo, César; Salas, Isabel; Alliende Rodríguez, Angélica; Amor, David J.; Godler, David E. (Nature, 2020)
      Fragile X syndrome (FXS) is caused by a hypermethylated full mutation (FM) expansion with >= 200 CGG repeats, and a decrease in FMR1 mRNA and its protein. However, incomplete silencing from FM alleles has been associated ...
    • Folic Acid Supplementation during Pregnancy Induces Sex-Specific Changes in Methylation and Expression of ... 
      Peñailillo, Reyna; Guajardo, Angélica; Llanos Silva, Miguel; Hirsch Birn, Sandra; Ronco Macchiavello, Ana María (Public Library Science, 2015)
      In the placenta, 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta-HSD2) limits fetal glucocorticoid exposure and its inhibition has been associated to low birth weight. Its expression, encoded by the HSD11B2 gene is ...
    • RNAseq reveals different transcriptomic responses to GA3 in early and midseason varieties before ripening ... 
      Kuhn, Nathalie; Maldonado, Jonathan; Ponce Ibáñez, Claudio Miguel; Arellano Sepúlveda, Macarena Patricia; Time, Alson; Multari, Salvatore; Martens, Stefan; Carrera, Esther; Donoso, José Manuel; Sagredo, Boris; Meisel, Lee Ann (Nature, 2021)
      Gibberellin (GA) negatively affects color evolution and other ripening-related processes in non-climacteric fruits. The bioactive GA, gibberellic acid (GA(3)), is commonly applied at the light green-to-straw yellow transition ...