Group electrophilicity as a model of nucleofugality in nucleophilic substitution reactions

Author	dc.contributor.author	Campodónico, Paola R.
Author	dc.contributor.author	Aizman, Arie	es_CL
Author	dc.contributor.author	Contreras Ramos, Renato	es_CL
Admission date	dc.date.accessioned	2008-12-15T16:01:03Z
Available date	dc.date.available	2008-12-15T16:01:03Z
Publication date	dc.date.issued	2006-05-10
Cita de ítem	dc.identifier.citation	CHEMICAL PHYSICS LETTERS Volume: 422 Issue: 4-6 Pages: 340-344 Published: MAY 10 2006	en
Identifier	dc.identifier.issn	0009-2614
Identifier	dc.identifier.uri	https://repositorio.uchile.cl/handle/2250/118767
Abstract	dc.description.abstract	We propose and test an empirical nucleofugality index to rank the leaving group ability of a series of molecular fragments present in nucleophilic substitution reactions of carbonyl and thiocarbonyl derivatives. The nucleofugality index is defined as the group electrophilicity of the leaving group embedded in the substrate that undergoes the nucleophilic attack. The reliability and usefulness of this new reactivity index is tested against experimental kinetic data.	en
Lenguage	dc.language.iso	en	en
Publisher	dc.publisher	ELSEVIER	en
Keywords	dc.subject	STRUCTURE-REACTIVITY CORRELATIONS	en
Título	dc.title	Group electrophilicity as a model of nucleofugality in nucleophilic substitution reactions	en
Document type	dc.type	Artículo de revista