Author | dc.contributor.author | Suárez, Rodrigo | es_CL |
Author | dc.contributor.author | Villalón, Aldo | |
Author | dc.contributor.author | Künzle, Heinz | es_CL |
Author | dc.contributor.author | Mpodozis Marín, Jorge | es_CL |
Admission date | dc.date.accessioned | 2011-05-03T18:30:14Z | |
Available date | dc.date.available | 2011-05-03T18:30:14Z | |
Publication date | dc.date.issued | 2009-11-24 | |
Cita de ítem | dc.identifier.citation | PLOS ONE, Volume: 4, Issue: 11, Article Number: e8005, 2009 | es_CL |
Identifier | dc.identifier.issn | 1932-6203 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/119187 | |
Abstract | dc.description.abstract | The vomeronasal system (VNS) mediates pheromonal communication in mammals. From the vomeronasal organ, two
populations of sensory neurons, expressing either Gai2 or Gao proteins, send projections that end in glomeruli distributed
either at the rostral or caudal half of the accessory olfactory bulb (AOB), respectively. Neurons at the AOB contact glomeruli
of a single subpopulation. The dichotomic segregation of AOB glomeruli has been described in opossums, rodents and
rabbits, while Primates and Laurasiatheres present the Gai2-pathway only, or none at all (such as apes, some bats and
aquatic species). We studied the AOB of the Madagascan lesser tenrec Echinops telfairi (Afrotheria: Afrosoricida) and found
that Gai2 and Gao proteins are expressed in rostral and caudal glomeruli, respectively. However, the segregation of
vomeronasal glomeruli at the AOB is not exclusive, as both pathways contained some glomeruli transposed into the
adjoining subdomain. Moreover, some glomeruli seem to contain intermingled afferences from both pathways. Both the
transposition and heterogeneity of vomeronasal afferences are features, to our knowledge, never reported before. The
organization of AOB glomeruli suggests that synaptic integration might occur at the glomerular layer. Whether intrinsic AOB
neurons may make synaptic contact with axon terminals of both subpopulations is an interesting possibility that would
expand our understanding about the integration of vomeronasal pathways. | es_CL |
Patrocinador | dc.description.sponsorship | The authors acknowledge financial support from FEBA (Fundacio´n para Estudios Biomédicos Avanzados), Mecesup UCH 0306, Conicyt (Término de
tesis doctoral), Fondecyt (1080094) and Deutsche Forschungsgemeinschaft (Ku 624/3-3). | es_CL |
Lenguage | dc.language.iso | en | es_CL |
Publisher | dc.publisher | PUBLIC LIBRARY SCIENCE | es_CL |
Keywords | dc.subject | ACCESSORY OLFACTORY-BULB | es_CL |
Título | dc.title | Transposition and Intermingling of G alpha i2 and G alpha o Afferences into Single Vomeronasal Glomeruli in the Madagascan Lesser Tenrec Echinops telfairi | es_CL |
Document type | dc.type | Artículo de revista | |