Show simple item record

Authordc.contributor.authorDelporte Vergara, Carla 
Authordc.contributor.authorBackhouse Erazo, Nadine es_CL
Authordc.contributor.authorNegrete Córdova, Rosa es_CL
Authordc.contributor.authorSalinas, P. es_CL
Authordc.contributor.authorRivas, P. es_CL
Authordc.contributor.authorCassels Niven, Brucees_CL
Authordc.contributor.authorSan Feliciano, A. es_CL
Admission datedc.date.accessioned2012-06-04T19:43:39Z
Available datedc.date.available2012-06-04T19:43:39Z
Publication datedc.date.issued1997-10-26
Cita de ítemdc.identifier.citationPHYTOTHERAPY RESEARCH, VOL. 12, p. 118–122, 1998.es_CL
Identifierdc.identifier.issn0951–418X
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/119441
Abstractdc.description.abstractThe acute toxicities of the global methanol extract of Solanum ligustrinum (Solanaceae) and the crude steroidal glycoalkaloids mixture were determined. The antipyretic, hypothermic and antiinflammatory activities of aqueous, global methanol, petroleum ether, dichloromethane and methanol extracts and crude steroidal glycoalkaloids mixture of the aerial parts were evaluated. All the extracts and the crude steroidal glycoalkaloids mixture were inactive in the hypothermic activity assay, nevertheless, they showed antipyretic and antiinflammatory activities. Scopoletin and b-sitosterol 3- O-b-D-glucoside were isolated and identified from the dichloromethane extract. The impure coumarin fraction showed antipyretic and antiinflammatory activities and b-sitosterol glucoside exhibited antiinflammatory activity. In the light of the results of several NOE experiments, the H-5 and H-8 signals in the 1H-NMR spectra of scopoletin were reassigned. The methanol global extract yielded a crude steroidal glycoalkaloids mixture with antipyretic and antiinflammatory effects.es_CL
Patrocinadordc.description.sponsorshipWe wish to extend our gratitude to I.F.S. (Grant F/1494-1)es_CL
Lenguagedc.language.isoenes_CL
Publisherdc.publisherJohn Wiley & Sons, Ltd.es_CL
Keywordsdc.subjectSolanum ligustrinumes_CL
Títulodc.titleAntipyretic, Hypothermic and Antiinflammatory Activities and Metabolites from Solanum ligustrinum Lood.es_CL
Document typedc.typeArtículo de revistaes_CL


Files in this item

Icon

This item appears in the following Collection(s)

Show simple item record