Diversity of cultivable fungi associated with Antarctic marine sponges and screening for their antimicrobial, antitumoral and antioxidant potential
Author
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Henríquez, Marlene
Author
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Vergara, Karen
es_CL
Author
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Norambuena, Javiera
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Author
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Beiza, Andrea
es_CL
Author
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Maza, Felipe
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Author
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Ubilla, Pamela
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Author
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Araya, Ivanna
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Author
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Chávez, Renato
es_CL
Author
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San Martín Barrientos, Aurelio
es_CL
Author
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Darias, José
es_CL
Author
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Darias, María J.
es_CL
Author
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Vaca Cerezo, Inmaculada
es_CL
Admission date
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2014-12-22T12:21:20Z
Available date
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2014-12-22T12:21:20Z
Publication date
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2014
Cita de ítem
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World J Microbiol Biotechnol (2014) 30:65–76
en_US
Identifier
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DOI: 10.1007/s11274-013-1418-x
Identifier
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https://repositorio.uchile.cl/handle/2250/119855
General note
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Artículo de publicación ISI
en_US
Abstract
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The diversity of sponge-associated fungi has
been poorly investigated in remote geographical areas like
Antarctica. In this study, 101 phenotypically different
fungal isolates were obtained from 11 sponge samples
collected in King George Island, Antarctica. The analysis
of ITS sequences revealed that they belong to the phylum
Ascomycota. Sixty-five isolates belong to the genera Geomyces,
Penicillium, Epicoccum, Pseudeurotium, Thelebolus,
Cladosporium, Aspergillus, Aureobasidium, Phoma,
and Trichocladium but 36 isolates could not be identified at
genus level. In order to estimate the potential of these
isolates as producers of interesting bioactivities, antimicrobial,
antitumoral and antioxidant activities of fungal
culture extracts were assayed. Around 51 % of the extracts,
mainly from the genus Geomyces and non identified
relatives, showed antimicrobial activity against some of the
bacteria tested. On the other hand, around 42 % of the
extracts showed potent antitumoral activity, Geomyces sp.
having the best performance. Finally, the potential of the
isolated fungi as producers of antioxidant activity seems to
be moderate. Our results suggest that fungi associated with
Antarctic sponges, particularly Geomyces, would be valuable
sources of antimicrobial and antitumoral compounds.
To our knowledge, this is the first report describing the
biodiversity and the metabolic potential of fungi associated
with Antarctic marine sponges.
en_US
Patrocinador
dc.description.sponsorship
This work was supported by FONDECYT grant 11090192,
Instituto Anta´rtico Chileno (INACH) and ‘‘Programa Bicentenario de
Ciencia y Tecnologı´a’’ (Chile) project PDA13.