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Authordc.contributor.authorQuispe, René 
Authordc.contributor.authorVillavicencio Reyes, Camila Patricia es_CL
Authordc.contributor.authorAddis, Elizabeth es_CL
Authordc.contributor.authorWingfield, John C. es_CL
Authordc.contributor.authorVásquez Salfate, Rodrigo es_CL
Admission datedc.date.accessioned2014-12-23T17:51:35Z
Available datedc.date.available2014-12-23T17:51:35Z
Publication datedc.date.issued2014
Cita de ítemdc.identifier.citationGeneral and Comparative Endocrinology 197 (2014) 65–72en_US
Identifierdc.identifier.otherdx.doi.org/10.1016/j.ygcen.2013.12.007
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/119865
General notedc.descriptionArtículo de publicación ISIen_US
Abstractdc.description.abstractAcross vertebrates, the hypothalamic–pituitary–adrenal axis is a conserved neuroendocrine network that responds to changing environments and involves the release of glucocorticoids into the blood. Few studies have been carried out concerning mammalian adrenal regulation in wild species either in the laboratory or field, and even fewer have been able to determine true glucocorticoid baselines. We studied the South-American caviomorph rodent Octodon degus, a diurnal and social mammal that has become an important species in the biological research. First, we determined the plasma cortisol baseline and the acute stress concentrations during the non-reproductive and mating seasons in free-living individuals. Second, using the same protocol we assessed the impact of long-term captivity on the adrenal function in wild-caught degus and degus born in laboratory. Third, we examined laboratory groups formed with degus taken from two distant natural populations; one of them originally occurs at the Andes Mountains in high altitude conditions. The data revealed seasonal modulation of basal cortisol in the wild associated with mating. In laboratory, degus presented higher cortisol stress responses, with greater magnitudes shown in degus born and reared in captivity. No differences between populations were found. The results suggest differential regulatory mechanisms between basal and stress-induced cortisol levels, and context dependence of cortisol modulation in a mammalian species.en_US
Patrocinadordc.description.sponsorshipThe study was supported by Grants FONDECYT 1090794, ICMP05- 002, and PFB-23-CONICYT, Chile, to R.A.V. J.C.W is grateful for support from Grant number IOS-0750540 from the US National Science Foundation.en_US
Lenguagedc.language.isoenen_US
Publisherdc.publisherElsevieren_US
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Keywordsdc.subjectDegusen_US
Títulodc.titleSeasonal variations of basal cortisol and high stress response to captivity in Octodon degus, a mammalian model speciesen_US
Document typedc.typeArtículo de revistaen_US


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile