Author | dc.contributor.author | Olea Azar, Claudio | |
Author | dc.contributor.author | Rigol Olsen, Carolina | es_CL |
Author | dc.contributor.author | Mendizábal Emaldía, Fernando | es_CL |
Author | dc.contributor.author | Cerecetto, Hugo | es_CL |
Author | dc.contributor.author | Di Maio, R. | es_CL |
Author | dc.contributor.author | González, Mercedes | es_CL |
Author | dc.contributor.author | Porcal, Williams | es_CL |
Author | dc.contributor.author | Morello Casté, Antonio | es_CL |
Author | dc.contributor.author | Repetto Scaramelli, Yolanda | es_CL |
Author | dc.contributor.author | Maya Arango, Juan | es_CL |
Admission date | dc.date.accessioned | 2009-05-14T17:41:38Z | |
Available date | dc.date.available | 2009-05-14T17:41:38Z | |
Publication date | dc.date.issued | 2005-06 | |
Cita de ítem | dc.identifier.citation | LETTERS IN DRUG DESIGN & DISCOVERY V.: 2, issue: 4, p.: 294-301: JUN 2005 | en |
Identifier | dc.identifier.issn | 1570-1808 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/120608 | |
Abstract | dc.description.abstract | In order to gain inside the mechanism of action of a series of benzo[1,2-c]1,2,5-oxadiazole N-oxide
derivatives with in vitro anti-trypanosomal activity, electrochemical and biological studies were performed.
Cyclic voltammetry and electron spin resonance spectroscopy were used to predict the bio-reduction
processes. Effects on the parasitic respiration were studied. | en |
Patrocinador | dc.description.sponsorship | This research was supported by FONDECYT 1000834,
7040037, 1020095, CSIC (UdelaR), CLEMENTE
ESTABLE and TWAS grants. We thank a scholarship for
C. Rigol from RELACQ. | |
Lenguage | dc.language.iso | english | en |
Publisher | dc.publisher | BENTHAM SCIENCE PUBL LTD. | en |
Keywords | dc.subject | Benzo[1,2-c]1,2,5-oxadiazole N-oxide | en |
Título | dc.title | Novel Benzo[1,2-c]1,2,5-Oxadiazole N-Oxide Derivatives as Antichagasic Agents: Chemical and Biological Studies | en |
Document type | dc.type | Artículo de revista | |