| Author | dc.contributor.author | Cordano, G. | |
| Author | dc.contributor.author | Yung Engel, Carlos | es_CL |
| Author | dc.contributor.author | Muñoz, S. | es_CL |
| Author | dc.contributor.author | Marrese Cabezas, Juan Carlos | es_CL |
| Author | dc.contributor.author | Muñoz de la Peña Bueno, Amalia | es_CL |
| Author | dc.contributor.author | Medina, Jorge | es_CL |
| Admission date | dc.date.accessioned | 2009-05-29T12:23:42Z | |
| Available date | dc.date.available | 2009-05-29T12:23:42Z | |
| Publication date | dc.date.issued | 1985-12 | |
| Cita de ítem | dc.identifier.citation | BOLETIN DE LA SOCIEDAD CHILENA DE QUIMICA 34(4):279-285 | en |
| Identifier | dc.identifier.issn | 0366-1644 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/120649 | |
| Abstract | dc.description.abstract | The incorporation of [1-(2-hydroxyethyl)-2-methyl-5-nitro-imidazole] (metronidazole), modified by treatment with succinic, glutaric and phtalic anhydrides on starch was studies. For the reaction the starch was previously activated with pyridine-water until gelification in the presence of dicyclohexylcarbodiimide (DCC) as a dehydrant agent and N,N,-dimethylaminopyridine (DAMP) as a catalyst. Incorporation of metronidazole on starch ranged up to 21.20%.
Products were characterized by IR spectroscopy, and the incorporated drug determined by releasing the nitrate ion from the metronidazole followed by its quantification by a colorimetric technique. | en |
| Lenguage | dc.language.iso | es | en |
| Publisher | dc.publisher | SOCIEDAD CHILENA DE QUIMICA | en |
| Keywords | dc.subject | STARCH | en |
| Título | dc.title | CHEMICAL BONDING OF METRONIDAZOLE SEMIESTERS WITH STARCH | en |
| Document type | dc.type | Artículo de revista | |
