Synthesis of new 1-benzyl-4,6-diaryl-2,3-dihydropyrazolo[3,4-b][1,4]diazepines

Abstract

The reaction of 4-amino-3-aryl-5-benzylaminopyrazoles (1a,b) with 3-dimethylaminopropiophenones (2) in ethanol with acetic acid gave 1-benzyl-4,6-diaryl-2,3-dihydropyrazolo[3,4-b] [1,4]diazepines (3a-h). The structure elucidation of the products is based on detailed nmr analysis (H-1, C-13 and DEPT).