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Tuning flux: autophagy as a target of heart disease therapy

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2011-05
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Xie, Min
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Tuning flux: autophagy as a target of heart disease therapy
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Author
  • Xie, Min;
  • Morales, Cindy R.;
  • Lavandero González, Sergio;
  • Hill, Joseph A.;
Abstract
Whereas we have known for some years of the participation of lysosomal mechanisms in heart disease, it is only recently that upstream mechanisms (autophagy) are being explored. The challenge for the future is to dissect the underlying circuitry and titrate the response into an optimal, proteostasis-promoting range in hopes of mitigating the ever-expanding epidemic of heart failure.
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Artículo de publicación ISI
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URI: https://repositorio.uchile.cl/handle/2250/121587
ISSN: 0268-4705
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CURRENT OPINION IN CARDIOLOGY 26 (3): 216-222
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