| Author | dc.contributor.author | Pérez, Hernán | |
| Author | dc.contributor.author | Ruiz, Samuel | es_CL |
| Author | dc.contributor.author | Núñez, Héctor | es_CL |
| Author | dc.contributor.author | White Ortiz, Allan | es_CL |
| Author | dc.contributor.author | Gotteland, Martín | es_CL |
| Admission date | dc.date.accessioned | 2009-06-24T11:26:23Z | |
| Available date | dc.date.available | 2009-06-24T11:26:23Z | |
| Publication date | dc.date.issued | 2007-05 | |
| Cita de ítem | dc.identifier.citation | INTERNATIONAL JOURNAL OF NEUROSCIENCE, V.: 117, issue: 5, p.: 627-642, MAY 2007. | en |
| Identifier | dc.identifier.issn | 0020-7454 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/123905 | |
| Abstract | dc.description.abstract | The effects of intracoerulear CRH and intraparaventricular prazosin on systolic
pressure, diastolic pressure and heart rate were studied in prenatally malnourished
hypertensive rats. At day 40 of life, (i) malnourished rats showed enhanced systolic
pressure, heart rate, and plasma corticosterone; (ii) intracoerulear CRH increased
systolic pressure and heart rate only in controls; (iii) intraparaventricular prazosin
decreased systolic pressure and heart rate only in malnourished rats; (iv) in controls,
prazosin did not prevent the stimulatory effect of CRH on the cardiovascular
parameters; in malnourished rats, prazosin allowed CRH regain its stimulatory
effects. Thus, coerulear activation by CRH would be involved in hypertension and
tachycardia developed by prenatally malnourished animals. | en |
| Patrocinador | dc.description.sponsorship | This research was supported by grant No. 1030626 from FONDECYT. | en |
| Lenguage | dc.language.iso | en | en |
| Publisher | dc.publisher | TAYLOR & FRANCIS LTD | en |
| Keywords | dc.subject | CRH | en |
| Título | dc.title | Coerulear activation by CRH and its role in hypertension induced by prenatal malnutrition in the rat | en |
| Document type | dc.type | Artículo de revista | |
