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Autordc.contributor.authorRojas Sobarzo, Loreto 
Autordc.contributor.authorOlivares Grohnert, Manuel es_CL
Autordc.contributor.authorBrito, Alex es_CL
Autordc.contributor.authorSuazo Romo, Miriam es_CL
Autordc.contributor.authorAraya, Magdalena es_CL
Autordc.contributor.authorPizarro Aguirre, Fernando es_CL
Fecha ingresodc.date.accessioned2014-01-08T12:55:05Z
Fecha disponibledc.date.available2014-01-08T12:55:05Z
Fecha de publicacióndc.date.issued2013
Cita de ítemdc.identifier.citationBiol Trace Elem Res (2013) 156:1–4en_US
Identificadordc.identifier.otherDOI 10.1007/s12011-013-9823-4
Identificadordc.identifier.urihttps://repositorio.uchile.cl/handle/2250/124043
Nota generaldc.descriptionArtículo de publicación ISIen_US
Resumendc.description.abstractCopper (Cu) deficiency has been reported to influence lipid metabolism, but the effects in humans are controversial. To evaluate the effects of 8 mg Cu/day supplementation (as copper sulfate) for 6 months on the lipid profile and hepatic function of apparently healthy men. The design was randomized double-blind placebo-controlled clinical trial. Subjects and methods: 60 apparently healthy males aged 18–51 years were randomly assigned to Cu supplementation (n =30) or placebo (n =30). There was a nonsignificant reduction of 17 % in total cholesterol in both groups after supplementation. A 23 % nonsignificant reduction was observed in LDL cholesterol levels in the supplemented group. There was a nonsignificant increase of HDL cholesterol of 47 and 66 % in the control and supplemented groups, respectively. Triglyceride levels over 150 mg/dl were found in 17 subjects supplemented and 13 controls at baseline and decreased after supplementation to seven and eight subjects, respectively. There were no effects on serum Cu concentration or ceruloplasmin (protein) and hepatic transaminases. Supplementation of 8 mg Cu for 6 months had no effect on lipid profile of apparently healthy Chilean men with adequate Cu status.en_US
Idiomadc.language.isoenen_US
Publicadordc.publisherSpringeren_US
Tipo de licenciadc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile*
Link a Licenciadc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Palabras clavesdc.subjectCopperen_US
Títulodc.titleCopper Supplementation at 8 mg Neither Affects Circulating Lipids nor Liver Function in Apparently Healthy Chilean Menen_US
Tipo de documentodc.typeArtículo de revista


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Excepto si se señala otra cosa, la licencia del ítem se describe como Attribution-NonCommercial-NoDerivs 3.0 Chile