Night time sleep macrostructure is altered in otherwise healthy 10-year-old overweight children
Author
dc.contributor.author
Chamorro Melo, Rodrigo
Author
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Algarín Crespo, Cecilia
es_CL
Author
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Garrido, M.
es_CL
Author
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Causa Morales, Leonardo Andrés
es_CL
Author
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Held Barrandeguy, Claudio
es_CL
Author
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Lozoff, B.
es_CL
Author
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Peirano Campos, Patricio
es_CL
Admission date
dc.date.accessioned
2014-12-15T13:05:03Z
Available date
dc.date.available
2014-12-15T13:05:03Z
Publication date
dc.date.issued
2014
Cita de ítem
dc.identifier.citation
International Journal of Obesity (2014) 38, 1120–1125
en_US
Identifier
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doi:10.1038/ijo.2013.238
Identifier
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https://repositorio.uchile.cl/handle/2250/124118
General note
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Artículo de publicación ISI
en_US
Abstract
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OBJECTIVE: Epidemiological evidence shows an inverse relationship between sleep duration and overweight/obesity risk.
However, there are few polysomnographic studies that relate the organization of sleep stages to pediatric overweight (OW).
We compared sleep organization in otherwise healthy OW and normal-weight (NW) 10-year-old children.
SUBJECTS: Polysomnographic assessments were performed in 37 NW and 59 OW children drawn from a longitudinal study
beginning in infancy. Weight and height were used to evaluate body mass index (BMI) according to international criteria. Non-rapid
eye movement (NREM) sleep (stages N1, N2 and N3), rapid eye movement (REM) sleep (stage R) and wakefulness (stage W) were
visually scored. Sleep parameters were compared in NW and OW groups for the whole sleep period time (SPT) and for each
successive third of it using independent Student’s t-tests or nonparametric tests. The relationship between BMI and sleep variables
was evaluated by correlation analyses controlling for relevant covariates.
RESULTS: The groups were similar in timing of sleep onset and offset, and sleep period time. BMI was inversely related to total
sleep time (TST) and sleep efficiency. OW children showed reduced TST, sleep efficiency and stage R amount, but higher stage W
amount. In analysis by thirds of the SPT, the duration of stage N3 episodes was shorter in the first third and longer in the second
third in OW children as compared with NW children.
CONCLUSIONS: Our results show reduced sleep amount and quality in otherwise healthy OW children. The lower stage R amount
and changes involving stage N3 throughout the night suggest that OW in childhood is associated with modifications not only in
sleep duration, but also in the ongoing night time patterns of NREM sleep and REM sleep stages.
en_US
Patrocinador
dc.description.sponsorship
This
study was supported by grants from Chilean Agency for Funding in Science and
Technology (CONICYT, Fondecyt 1110513 and 1120319) and the US National
Institutes of Health (NIH R01 HD33487).