This work aimed to provide a thorough description of the polyphenolic composition of five
Latin-American fruits of increasing interest, which have certain anti-diabetic effects (ac¸aı´,
maqui, Cape gooseberry, papaya and noni), and to correlate their antioxidant capacity and
anti-diabesity activities (lipase and a-glucosidase inhibition), and examine their potential
use by the food industry. The phytochemical profiling of the fruits revealed a wide range
of bioactive phenolics. The inhibition of pancreatic lipase was significant for maqui, and
maqui and papaya were the best inhibitors of a-glucosidase. Regarding the DPPH, ABTS +
and FRAP assays, maqui berries displayed the highest activity. The ORAC method and
the superoxide radical scavenging assays revealed maqui and ac¸aı´ as the best performers.
These Latin-American fruits are of great value regarding nutrition and health benefits, and
the development of products for the control of diabetes and obesity.
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The Authors express their gratitude to the Spanish Ministry of
Economy and Competitivity for the funding through the
CICYT project AGL2011-23690 and the CONSOLIDER-INGENIO
2010 Research Project FUN-C-FOOD (CSD2007-00063). Part of
this work was carried out in international research collaboration
within the CYTED Program (Ref. 112RT0460) CORNUCOPIA
Thematic Network (URL: redcornucopia.org). AGV also
thanks the CSIC and the European Social Funds for the JAE
Predoctoral Grant. NB was funded by the FPU Fellowship
Program of the Spanish Ministry of Education