About
Contact
Help
Sending publications
How to publish
Advanced Search
View Item 
  •   Home
  • Facultad de Medicina
  • Artículos de revistas
  • View Item
  •   Home
  • Facultad de Medicina
  • Artículos de revistas
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Browse byCommunities and CollectionsDateAuthorsTitlesSubjectsThis CollectionDateAuthorsTitlesSubjects

My Account

Login to my accountRegister
Biblioteca Digital - Universidad de Chile
Revistas Chilenas
Repositorios Latinoamericanos
Tesis LatinoAmericanas
Tesis chilenas
Related linksRegistry of Open Access RepositoriesOpenDOARGoogle scholarCOREBASE
My Account
Login to my accountRegister

Síndrome de restauración inmune asociado a tratamiento antirretroviral y criptococosis meníngea. Caso clínico

Artículo
Thumbnail
Open/Download
IconSaez_David.pdf (1.430Mb)
Publication date
2006-10
Metadata
Show full item record
Cómo citar
Sáez Méndez, David
Cómo citar
Síndrome de restauración inmune asociado a tratamiento antirretroviral y criptococosis meníngea. Caso clínico
.
Copiar
Cerrar

Author
  • Sáez Méndez, David;
  • Bahamondes M., Laura;
  • Lam E., Gislaine;
  • Arellano R., Luz;
  • Lillo Zurita, Patricia;
Abstract
The objective of high activity antiretroviral therapy (HAART) inpatients with AIDS, is to obtain immune restoration. This means a reduction of the viral load and restitution of the CD4 cell count. A decreased rate of HIV replication improves both the number and function of CD4 cells. Nevertheless, this treatment sometimes results in the reappearance of previous symptoms from? treated conditions due to opportunistic infections (ie: tuberculosis, criptococcosis, bepatitis, Pneumocystis jirovesi, toxoplasmosis, etc) or non, infections condition such as sarcoidosis, Graves disease or Kaposi sarcoma. This is known as Inflammatory Reconstitution Immune Syndrome (IRIS). We report a 3 7 year-old zvonlan in stage C3-AIDS with a previous criptococcal meningitis. She was treated, achieving a marked improvement with treatment and subsequent suppressive therapy with fluconazole 200 mg/day. IRIS appeared after 8 months of ongoing antiretroviral therapy with immune restoration with the development of aseptic meningitis and intracranial hypertension. The opportunistic agent could not be identified by cultures. Additional laboratory tests excluded toxoplasmosis, tuberculosis. bacterial cerebral abscesses. syphilitic cerebral gummas,. and lymphoma. Brain CT and magnetic resonance studies were compatible with brain vasculitis and leptomeningitis. The patient condition improved with general measures, such as a repeated lumbar punctures and non steroidal anti-inflammatory drugs. We conclude that this patient bad all IRIS due to a Oyptococcus neoformans antigen.
Identifier
URI: https://repositorio.uchile.cl/handle/2250/127950
ISSN: 0034-9887
Quote Item
REVISTA MEDICA DE CHILE Volume: 134 Issue: 10 Pages: 1310-1314 Published: OCT 2006
Collections
  • Artículos de revistas
xmlui.footer.title
31 participating institutions
More than 73,000 publications
More than 110,000 topics
More than 75,000 authors
Published in the repository
  • How to publish
  • Definitions
  • Copyright
  • Frequent questions
Documents
  • Dating Guide
  • Thesis authorization
  • Document authorization
  • How to prepare a thesis (PDF)
Services
  • Digital library
  • Chilean academic journals portal
  • Latin American Repository Network
  • Latin American theses
  • Chilean theses
Dirección de Servicios de Información y Bibliotecas (SISIB)
Universidad de Chile

© 2020 DSpace
  • Access my account