| Author | dc.contributor.author | Luchsinger Farías, Vivian | es_CL |
| Author | dc.contributor.author | Elgueta Noy, Andrea | es_CL |
| Author | dc.contributor.author | Avendaño, Luis Fidel C. | |
| Admission date | dc.date.accessioned | 2010-01-28T13:51:44Z | |
| Available date | dc.date.available | 2010-01-28T13:51:44Z | |
| Publication date | dc.date.issued | 2008-07 | |
| Cita de ítem | dc.identifier.citation | JOURNAL OF CLINICAL VIROLOGY Volume: 42 Issue: 3 Pages: 260-263 Published: JUL 2008 | en_US |
| Identifier | dc.identifier.issn | 1386-6532 | |
| Identifier | dc.identifier.other | 10.1016/j.jcv.2008.03.024 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/128398 | |
| Abstract | dc.description.abstract | Background: Human respiratory syncytial virus (HRSV) is a major cause of severe lower respiratory tract infection (LRI) in children. Distinct variants of the viruses have been described.
Objective: The objective was to compare the antigenic and genetic variability of HRSV strains recovered from infants admitted to two hospitals during one epidemic in a big city.
Study design: We analyzed nasopharyngeal aspirates from 201 infants admitted for LRI to two hospitals during 2002 in Santiago, Chile. The analyses were carried out using a panel of monoclonal antibodies against G glycoprotein epitopes (EIA) and RFLP for N and G genes.
Results: No differences in HRSV groups A/B and in N patterns distribution were observed among both hospitals. On the contrary, antigenic and genetic G patterns displayed a wide diversity of strains circulating during one epidemic, in one big city.
Conclusions: RSV variability assessment depended rather on the tool used for analysis than on the geographical location. | en_US |
| Lenguage | dc.language.iso | en | en_US |
| Publisher | dc.publisher | ELSEVIER | en_US |
| Keywords | dc.subject | GROUP-A | en_US |
| Título | dc.title | Human respiratory syncytial virus genomic and antigenic variants isolated in two hospitals during one epidemic, in Santiago, Chile | en_US |
| Document type | dc.type | Artículo de revista | |
