Temporal variation in Trypanosoma cruzi lineages from the native rodent Octodon degus in semiarid Chile
Author
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Botto Mahan, Carezza
Author
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Rojo, Gemma
Author
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Sandoval Rodríguez, Alejandra
Author
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Peña, Fabiola
Author
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Ortiz, Sylvia
Author
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Solari Illescas, Aldo
Admission date
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2015-12-31T14:00:13Z
Available date
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2015-12-31T14:00:13Z
Publication date
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2015
Cita de ítem
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Acta Tropica 151 (2015) 178–181
en_US
Identifier
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DOI: 10.1016/j.actatropica.2015.06.008
Identifier
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https://repositorio.uchile.cl/handle/2250/136111
General note
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Artículo de publicación ISI
en_US
Abstract
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Chagas disease is a zoonosis caused by the protozoan parasite Trypanosome cruzi and transmitted by triatomine insects to several mammalian species acting as reservoir hosts. In the present study, we assess T. cruzi-prevalence and DTU composition of the endemic rodent Octodon degus from a hyper-endemic area of Chagas disease in Chile. Parasite detection is performed by PCR assays on blood samples of individuals captured in the austral summers of 2010-2013. The infection level in rodents differed in the summers of these four years between 18% and 70%. Overall, infected O. degus showed similar T. cruzi-DTU composition (TcI,TcII, TcV and TcVI lineages) among years, corresponding to single and mixed infection, but the relative importance of each DTU changed among years. In 2013, we detected that only three out of the four T. cruzi-DTU found in O. degas were present in the endemic triatomine Mepria spinolai. We suggest that O. degus, an abundant long-lived rodent, is an important native reservoir of T. cruzi in the wild transmission cycle of Chagas disease and it is able to maintain all the T. cruzi-DTUs described in semiarid Chile.