Original footage of the Chilean miners with manganism published in Neurology in 1967

Abstract

Manganism has captured the imagination of neurologists for more than a century because of its similarities to Parkinson disease and its indirect but seminal role in the l-dopa miracle. We present unpublished footage of the original case series reported in Neurology (R) in 1967 by Mena and Cotzias depicting the typical neurologic signs of manganism in 4 Chilean miners and their response to high doses of l-dopa.