Synthesis, characterization and antibacterial activity of cobalt(III) complex with phenanthroline and maltose

Abstract

The mononuclear cobalt(III) complex derived from 1,10-phenanthroline and maltose ([Co(phen)(2)maltose]Cl-2 center dot 3H(2)O) (1) has been synthesized and characterized in aqueous solution. Its characterization was based on its optical and spectroscopic properties.

The antimicrobial activity of this complex was screened in vitro against the microorganisms Escherichia coli DH5 alpha, Salmonella enterica sv Enteritidis ISP/953, Klebsiella pneumoniae RYC492, Pseudomonas aeruginosa PAO1, Enterococcus faecalis ATCC 29212, Bacillus cereus GCA234, Micrococcus sp. Staphylococcus aureus ATCC25923.

Complex (1) showed antibacterial activity with a bacteriostatic effect over Gram positive and negative bacteria. The cytotoxicity of complex (1) was tested in vitro on human embryonic kidney cells.