Trombolisis intravenosa en accidente cerebro vascular isquémico agudo en un hospital público de Chile: Análisis prospectivo de 54 casos
Author
dc.contributor.author
Guevara O., Carlos
Author
dc.contributor.author
Bulatova, Kateryna
Author
dc.contributor.author
Aravena, Felipe
Author
dc.contributor.author
Caba, Sheila
Author
dc.contributor.author
Monsalve, Juan
Author
dc.contributor.author
Lara, Hugo
Author
dc.contributor.author
Nieto, Elena
Author
dc.contributor.author
Navarrete, Isabel
Author
dc.contributor.author
Morales, Marcelo
Admission date
dc.date.accessioned
2016-10-27T19:10:58Z
Available date
dc.date.available
2016-10-27T19:10:58Z
Publication date
dc.date.issued
2016
Cita de ítem
dc.identifier.citation
Rev Med Chile 2016; 144: 442-450
es_ES
Identifier
dc.identifier.issn
0034-9887
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/141043
Abstract
dc.description.abstract
Background: Intravenous thrombolysis with recombinant tissue plasminogen
activator (rt-PA) reduces disability in patients with ischemic stroke. However, its
implementation in Chilean public general hospitals has been slow and faces some
difficulties. Aim: To analyze the results of an intravenous thrombolysis protocol
implementation in a public general hospital. Material and Methods: During a
lapse of 28 months a standardized protocol for intravenous thrombolysis implemented
in the emergency room of a public hospital, was prospectively evaluated.
Fifty four patients with ischemic stroke were treated and assessed three months
later as outpatients. Results: At three months of follow-up, 66.4% of patients
subjected to thrombolysis had a favorable evolution, defined as having 0 to 1
points in the modified Rankin scale. Intracerebral hemorrhage rate was 11.1%,
including 5.5% of symptomatic intracerebral hemorrhage. Four percent of
patients had systemic bleeding complications after thrombolysis. The mortality
rate was 14.8%. Conclusions: The success rates, mortality, and complications
rate were comparable to the results obtained in international studies, despite of
the absence of a stroke unit to manage stroke and its complications.